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  1. To evaluate the impact of embryo quality and quantity, specifically a poor quality embryo (PQE) in combination with a good quality embryo (GQE), by double embryo transfer (DET) on the live birth rate (LBR) and...

    Authors: Cheng Zeng, Rui-Hui Lu, Xin Li, Sheng Wang, Yan-Rong Kuai and Qing Xue
    Citation: Reproductive Biology and Endocrinology 2024 22:26
  2. Insulin resistance (IR) is known to be prevalent amongst women with polycystic ovarian syndrome (PCOS). Its presence has been linked to chronic anovulation and marked long term complications in women. Hence, i...

    Authors: Olugbenga Ojatokunbo Runsewe, Abiodun Adeniyi Adewunmi, Gbenga Olorunfemi, Abimbola Tawaqualit Ottun, Ayokunle Moses Olumodeji, Babalola Ogungbemile and Tamramat Iyabo Runsewe-Abiodun
    Citation: Reproductive Biology and Endocrinology 2024 22:25
  3. Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders in females of childbearing age. Various types of ovarian cells work together to maintain normal reproductive function...

    Authors: Shumin Li, Yimeng Li, Yu Sun, Gengchen Feng, Ziyi Yang, Xueqi Yan, Xueying Gao, Yonghui Jiang, Yanzhi Du, Shigang Zhao, Han Zhao and Zi-Jiang Chen
    Citation: Reproductive Biology and Endocrinology 2024 22:24
  4. Recurrent implantation failure (RIF) represents a vague clinical condition with an unclear diagnostic challenge that lacks solid scientific underpinning. Although euploid embryos have demonstrated consistent i...

    Authors: A. Almohammadi, F. Choucair, L. El Taha, H. Burjaq, M. Albader, A. B. Cavanillas and Johnny T. Awwad
    Citation: Reproductive Biology and Endocrinology 2024 22:23
  5. The quandary known as the Intracytoplasmic Sperm Injection (ICSI) paradox is found at the juncture of Assisted Reproductive Technology (ART) and ‘andrological ignorance’ – a term coined to denote the undervalu...

    Authors: Pallav Sengupta, Sulagna Dutta, Ravindran Jegasothy, Petr Slama, Chak-Lam Cho and Shubhadeep Roychoudhury
    Citation: Reproductive Biology and Endocrinology 2024 22:22
  6. Biomarker identification could help in deciphering endometriosis pathophysiology in addition to their use in the development of non invasive diagnostic and prognostic approaches, that are essential to greatly ...

    Authors: Axelle Brulport, Mathilde Bourdon, Daniel Vaiman, Christian Drouet, Khaled Pocate-Cheriet, Kheira Bouzid, Louis Marcellin, Pietro Santulli, Carole Abo, Maxime Jeljeli, Sandrine Chouzenoux, Charles Chapron, Frédéric Batteux, Camille Berthelot and Ludivine Doridot
    Citation: Reproductive Biology and Endocrinology 2024 22:21
  7. Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation. One of the hormone receptors...

    Authors: Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer and Nadia Stamm
    Citation: Reproductive Biology and Endocrinology 2024 22:20
  8. Previous studies have suggested that oil-based contrast agents used during hysterosalpingography (HSG) in infertile patients can enhance fertility. However, limited research has investigated the effect of oil-...

    Authors: Baoli Xie, Yingqin Huang, Fu Hang, Jiaxin Yu, Qianwen Hu, Jiaxu Li and Aiping Qin
    Citation: Reproductive Biology and Endocrinology 2024 22:19
  9. Standard management for intrauterine lesions typically involves initial imaging followed by operative hysteroscopy for suspicious findings. However, the efficacy of routine outpatient hysteroscopy in women und...

    Authors: Jung-Hsiu Hou, Buo-Jia Lu, Ya-Li Huang, Chih-Heng Chen and Chi-Huang Chen
    Citation: Reproductive Biology and Endocrinology 2024 22:18
  10. In our previous investigation, we revealed a significant increase in the expression of microRNA-6881-3p (miR-6881-3p) in follicular fluid granulosa cells (GCs) from women with diminished ovarian reserve (DOR) ...

    Authors: Wenhan Ju, Shuai Zhao, Haicui Wu, Yi Yu, Yuan Li, Danqi Liu, Fang Lian and Shan Xiang
    Citation: Reproductive Biology and Endocrinology 2024 22:17
  11. During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support embryonic development. Interferon-λ (IFN-λ) is a novel, non-...

    Authors: Kezhen Yao, Quanmin Kang, Kai Chen, Biwei Shi and Xiaofen Jin
    Citation: Reproductive Biology and Endocrinology 2024 22:16
  12. Erythropoietin (Epo) is a potent vascular growth factor that induces angiogenesis and antiapoptotic signalling. We investigated whether the development of numerous follicles and corpora lutea during in vitro f...

    Authors: Merituuli Rekola, Kati Korhonen, Leila Unkila-Kallio, Henrik Alfthan, Vedran Stefanovic, Aila Tiitinen, Tomi S. Mikkola and Hanna Savolainen-Peltonen
    Citation: Reproductive Biology and Endocrinology 2024 22:14
  13. Increasing number of studies have demonstrated certain patterns of microbial changes in gynecological diseases; however, the interaction between them remains unclear. To evaluate the consistency or specificity...

    Authors: Ziwei Zhou, Yifei Feng, Lishan Xie, Song Ma, Zhaoxia Cai and Ying Ma
    Citation: Reproductive Biology and Endocrinology 2024 22:13
  14. Several studies have demonstrated that iDAScore is more accurate in predicting pregnancy outcomes in cycles without preimplantation genetic testing for aneuploidy (PGT-A) compared to KIDScore and the Gardner c...

    Authors: Chun-I Lee, Chun-Chia Huang, Tsung-Hsien Lee, Hsiu-Hui Chen, En-Hui Cheng, Pin-Yao Lin, Tzu-Ning Yu, Chung-I Chen, Chien-Hong Chen and Maw-Sheng Lee
    Citation: Reproductive Biology and Endocrinology 2024 22:12
  15. Polycystic ovary syndrome (PCOS) is the main cause of anovulatory infertility in women of reproductive age, and low-grade chronic inflammation plays a key role in the occurrence and development of PCOS. Howeve...

    Authors: Jie Shang, Siyu Wang, Aiyuan Wang, Fang Li, Jing Zhang, Jin Wang, Rui Lv, Haixia Chen, Xiaohuan Mu, Kai Zhang, Xiaohong Bai and Ye Tian
    Citation: Reproductive Biology and Endocrinology 2024 22:11
  16. Women with adenomyosis are characterized by having defective decidualization, impaired endometrial receptivity and/or embryo-maternal communication, and implantation failure. However, the molecular mechanisms ...

    Authors: Elena Juárez-Barber, Ana Corachán, María Cristina Carbajo-García, Amparo Faus, Carmen Vidal, Juan Giles, Antonio Pellicer, Irene Cervelló and Hortensia Ferrero
    Citation: Reproductive Biology and Endocrinology 2024 22:10
  17. In Italy the fertility rate is very low, and an increasing number of patients are infertile and require treatments. The Italian Law concerning the safety of patient care, and the professional liability of heal...

    Authors: Stefano Palomba, Paola Viganò, Sandrine Chamayou, Zaira Donarelli, Maria Paola Costantini, Roberto Marci, Paola Piomboni, Egidio Fino, Luigi Montano, Antonino Guglielmino and Edgardo Somigliana
    Citation: Reproductive Biology and Endocrinology 2024 22:9
  18. The process of gamete formation and early embryonic development involves rapid DNA replication, chromosome segregation and cell division. These processes may be affected by mutations in the BRCA1/2 genes. The aim...

    Authors: Ilana Weizel, Tal Shavit, Yulia Shuli, Chana Adler Lazarovich, Rivka Halevi, Tal Ben Ari, Shira Yaacobi-Artzi, Yaakov Bentov, Baruch Feldman and Anat Hershko Klement
    Citation: Reproductive Biology and Endocrinology 2024 22:8
  19. The maximum daily dose of follitropin delta for ovarian stimulation in the first in vitro fertilization cycle is 12 μg (180 IU), according to the algorithm developed by the manufacturer, and based on patient’s...

    Authors: Oscar Barbosa Duarte-Filho, Eduardo Hideki Miyadahira, Larissa Matsumoto, Lucas Yugo Shiguehara Yamakami, Renato Bussadori Tomioka and Sergio Podgaec
    Citation: Reproductive Biology and Endocrinology 2024 22:7
  20. A fine-tuned pro-inflammatory and anti-inflammatory balance in the follicular unit is essential for cumulus expansion and successful ovulation. While the long pentraxin 3 (PTX3) gene is required for the expans...

    Authors: Aynur Ersahin, Onder Celik, Nur D. Gungor, Nilufer Celik, Sureyya Melil, Meltem Yardim, Semih Dalkilic, Cenk Ersahin, Ece Dogukargin, Sudenaz Celik and Ramazan F. Akkoc
    Citation: Reproductive Biology and Endocrinology 2024 22:6
  21. Neuroepithelial transforming gene 1 (NET1) is a RhoA subfamily guanine nucleotide exchange factor that governs a wide array of biological processes. However, its roles in meiotic oocyte remain unclear. We here...

    Authors: Shiwei Wang, Xuan Wu, Mengmeng Zhang, Siyu Chang, Yajun Guo, Shuang Song, Shizhen Dai, Keliang Wu and Shenming Zeng
    Citation: Reproductive Biology and Endocrinology 2024 22:5
  22. This study aimed to investigate the relationship between serum testosterone levels and the risk of congestive heart failure (CHF) in adult males. Previous research has suggested a potential link between serum ...

    Authors: Xiangpeng Zhan, Yang Liu, Tao Chen, Hao Wan, Situ Xiong, Sheng Li, Xinxi Deng, Luyao Chen and Bin Fu
    Citation: Reproductive Biology and Endocrinology 2024 22:4
  23. Chronic inflammation plays a vital role in the development of gestational diabetes mellitus (GDM). Studies in mouse models show that neutrophil serine proteases (NSPs), neutrophil elastase (NE) and proteinase-...

    Authors: Lihong Wang, Zhoujunhao Zhou, Xinming Xu, Yue Li, Rui Zhang, Zhiyan Yu, Xinmei Huang, Shufei Zang and Tiange Sun
    Citation: Reproductive Biology and Endocrinology 2024 22:2
  24. The coronavirus disease (COVID-19) pandemic has seriously impacted the mental and sexual health of the general population. Patients dealing with infertility constitute a unique subset within society, susceptib...

    Authors: Jing Qi, Meng Sun, Xingchen Yue, Xintong Hong, Meng Dong and Jichun Tan
    Citation: Reproductive Biology and Endocrinology 2024 22:1
  25. To explore the role of anti-Mullerian hormone (AMH) in predicting the need to step up recombinant FSH (rFSH) dose following long GnRH agonist protocol in IVF/ICSI cycles of polycystic ovarian syndrome (PCOS) w...

    Authors: Hui Huang, Haijie Gao, Yingying Shi, Bingbing Deng, Xuemei He, Jin Lin and Ping Li
    Citation: Reproductive Biology and Endocrinology 2023 21:121
  26. Survival rates of young women undergoing cancer treatment have substantially improved, with a focus on post-treatment quality of life. Ovarian tissue transplantation (OTT) is a viable option to preserve fertil...

    Authors: Baoli Xie, Jiaxu Li, Yingqin Huang, Fu Hang, Qianwen Hu, Jiaxin Yu and Aiping Qin
    Citation: Reproductive Biology and Endocrinology 2023 21:120
  27. To evaluate the clinical effectiveness and pregnancy rate after hysteroscopic resection (HR) and/or vaginal repair (VR) in patients with cesarean scar defect (CSD).

    Authors: Guoxia Yang, Jiamin Wang, Yajie Chang and Yuqing Chen
    Citation: Reproductive Biology and Endocrinology 2023 21:119
  28. Several studies have explored which COS protocol yields a higher blastocyst euploidy rate, but findings have been inconsistent. The present study aimed to explore whether controlled ovarian stimulation (COS) p...

    Authors: Bixia Huang, Hui Li, Bin Xu, Ning Li, Xiaofei Wang, Yanping Li and Jing Zhao
    Citation: Reproductive Biology and Endocrinology 2023 21:118
  29. Premature progesterone (P) rise during IVF stimulation reduces endometrial receptivity and is associated with lower pregnancy rates following embryo transfer (ET), which can influence provider recommendation f...

    Authors: Victoria G. Wesevich, Serin I. Seckin, Dawn A. Kelk, Amanda N. Kallen and Pinar H. Kodaman
    Citation: Reproductive Biology and Endocrinology 2023 21:117
  30. The incidence of Y chromosome microdeletions varies among men with infertility across regions and ethnicities worldwide. However, comprehensive epidemiological studies on Y chromosome microdeletions in Chinese...

    Authors: Dongjia Chen, Guoqing Fan, Xianqing Zhu, Qinyun Chen, Xuren Chen, Feng Gao, Zexin Guo, Peng Luo and Yong Gao
    Citation: Reproductive Biology and Endocrinology 2023 21:116
  31. The 25-hydroxyvitamin D3 (25 (OH) D3) is crucial for follicular development. This study aimed to investigate the relationship between the level of 25 (OH) D3 in endometriosis patients, pregnancy outcomes of in...

    Authors: Rui Hu, Leilei Li, Lanlan Liang, YuXin Qi, Xiaoling Ma and Yuan Yang
    Citation: Reproductive Biology and Endocrinology 2023 21:115
  32. Infertility affects approximately 10–15% of reproductive-age men worldwide, and genetic causes play a role in one-third of cases. As a Bin-Amphiphysin-Rvs (BAR) domain protein, protein interacting with C-kinas...

    Authors: Jing Jin, Kaiqiang Li, Yaoqiang Du, Fang Gao, Zhen Wang and Weixing Li
    Citation: Reproductive Biology and Endocrinology 2023 21:114
  33. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. This disorder affects 6–15% of women of childbearing age worldwide. It is diagnosed with hyperandrogenism, polycystic ovaries, a...

    Authors: Leili Rahmatnezhad, Lida Moghaddam-Banaem, Tahereh Behroozi-Lak, Afshin Shiva and Javad Rasouli
    Citation: Reproductive Biology and Endocrinology 2023 21:113
  34. This study aimed to assess the predictive value of endometrial blood flow branches on pregnancy outcomes after hormone replacement therapy-frozen embryo transfer (HRT-FET).

    Authors: Xue Ke, Xue-fei Liang, Yong-hong Lin and Fang Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:112
  35. Polycystic ovary syndrome (PCOS) is a heterogeneous functional endocrine disorder associated with a low-grade, chronic inflammatory state. Patients with PCOS present an increased risk of metabolic comorbiditie...

    Authors: Awoniyi O. Awonuga, Olivia G Camp and Husam M Abu-Soud
    Citation: Reproductive Biology and Endocrinology 2023 21:111
  36. TUBB8, a crucial gene encoding microtubule protein, plays a pivotal role in cellular processes. Deleterious TUBB8 variants have been shown to significantly hinder oocyte maturation. In this study, we conducted...

    Authors: Tianli Chang, Jing Zhao, Qi Li, Anning Meng, Qiuping Xia, Yanping Li, Wenpei Xiang and Zhongyuan Yao
    Citation: Reproductive Biology and Endocrinology 2023 21:109
  37. It has been long known that thyroid hormone regulates placental villi development, which is associated with the occurrence of miscarriage. However, whether abnormal thyroid hormone metabolism and transport in ...

    Authors: Zhen Yu, Xinghao Feng, Zhongshan Lin, Xuan Li, Shiyue Su, Huiru Cheng, Yuanyuan Yang and Zhaolian Wei
    Citation: Reproductive Biology and Endocrinology 2023 21:108
  38. Advanced endometriosis is associated with a reduction of IVF success. Surgical damage to the ovarian reserve following the excision of endometriomas has been claimed as a critical factor in the explanation of ...

    Authors: Edgardo Somigliana, Letizia Li Piani, Alessio Paffoni, Noemi Salmeri, Michele Orsi, Laura Benaglia, Paolo Vercellini and Paola Vigano’
    Citation: Reproductive Biology and Endocrinology 2023 21:107
  39. Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been thoroughly studied in various biological systems, including the testis. Research over the last decade has generated signi...

    Authors: Meghali Joshi, Shruti Sethi, Poonam Mehta, Anamika Kumari and Singh Rajender
    Citation: Reproductive Biology and Endocrinology 2023 21:106
  40. This large, single-center, retrospective cohort study was aimed to explore the effect of female body mass index (BMI) on ectopic pregnancy (EP) following fresh and frozen-thawed embryo transfers (ET).

    Authors: Xiaofei Ge, Keyan Wang, Yingpu Sun and Zhiqin Bu
    Citation: Reproductive Biology and Endocrinology 2023 21:105
  41. With advanced maternal age, abnormalities during oocyte meiosis increase significantly. Aneuploidy is an important reason for the reduction in the quality of aged oocytes. However, the molecular mechanism of a...

    Authors: Bichun Guo, Sainan Zhang, Shanshan Wang, Huidan Zhang, Junshun Fang, Nannan Kang, Xin Zhen, Yang Zhang, Jidong Zhou, Guijun Yan, Haixiang Sun, Lijun Ding and Chuanming Liu
    Citation: Reproductive Biology and Endocrinology 2023 21:103
  42. Endometriosis is a condition that significantly affects the quality of life of about 10 % of reproductive-aged women. It is characterized by the presence of tissue similar to the uterine lining (endometrium) o...

    Authors: Krystian Zieliński, Dajana Drabczyk, Michał Kunicki, Damian Drzyzga, Anna Kloska and Jacek Rumiński
    Citation: Reproductive Biology and Endocrinology 2023 21:102
  43. The current routine endometrial preparation protocol for women with polycystic ovary syndrome (PCOS) is hormone replacement treatment (HRT). Letrozole is rarely used in frozen embryo cycles. Evidence confirmin...

    Authors: Xiaojuan Wang, Yuan Li, Hongzhuan Tan, Sufen Cai, Shujuan Ma, Yangqin Peng, Hui Guo, Xiaofeng Li, Yi Tang, Shunji Zhang, Ge Lin and Fei Gong
    Citation: Reproductive Biology and Endocrinology 2023 21:101
  44. Endometriosis-related infertility is a common worldwide reproductive health concern. Despite ongoing research, the causes of infertility remain unclear. Evidence suggests that epigenetic regulation is crucial ...

    Authors: Xiaoou Li, Jie Jin, Xuefeng Long, Ruiwen Weng, Wenqian Xiong, Jiaxin Liang, Junjun Liu, Jingwen Sun, Xueqin Cai, Ling Zhang and Yi Liu
    Citation: Reproductive Biology and Endocrinology 2023 21:99
  45. To determine whether there is a correlation between stiffness measured by strain elastography and the severity of dysmenorrhea and to determine the value of elastography in evaluating severe dysmenorrhea in pa...

    Authors: Qianhui Ren, Xiangyi Dong, Ming Yuan, Xue Jiao, Hao Sun, Zangyu Pan, Xinyu Wang, Guowei Tao and Wang Guoyun
    Citation: Reproductive Biology and Endocrinology 2023 21:98

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