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  1. Content type: Short communication

    Blastomere movement (BMov) occurs after the first cell division in human embryos. This movement has been suggested as a prognostic parameter for pregnancy outcome prediction following cleavage-stage embryo tra...

    Authors: Kazuki Ohata, Kenji Ezoe, Tetsuya Miki, Hirofumi Morita, Ryoma Tsuchiya, Shigeru Kaneko, Tadashi Okimura, Kazuo Uchiyama, Akiko Yabuuchi, Tamotsu Kobayashi, Markus Montag and Keiichi Kato

    Citation: Reproductive Biology and Endocrinology 2019 17:44

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  2. Content type: Research

    Almost all of the previous studies related with co-administration of letrozole in IVF cycles were performed in poor responders and letrozole may reduce the total gonadotropin dose required for ovarian stimulat...

    Authors: Xiaoyi Yang, Ge Lin, Guangxiu Lu and Fei Gong

    Citation: Reproductive Biology and Endocrinology 2019 17:43

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  3. Content type: Short communication

    Our previous studies showed that the miRNA clusters, miR-183-96-182 and miR-212-132, may be critical in promoting luteal cell survival and progesterone production in both bovine and humans. To further understa...

    Authors: Bushra T. Mohammed, Cristina L. Esteves and F. Xavier Donadeu

    Citation: Reproductive Biology and Endocrinology 2019 17:41

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  4. Content type: Research

    The maternal body forms a wireless communication system with the embryo through the blood circulation system. Obviously, direct sampling from early embryos is damaging. Therefore, we detected changes in the co...

    Authors: Miao Zhao, Tingting Liu and Guangchang Pang

    Citation: Reproductive Biology and Endocrinology 2019 17:40

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  5. Content type: Review

    Maternal nutrition during pregnancy has life-long consequences for offspring. However, the effects of maternal overnutrition and/ or obesity on fetal growth remain poorly understood, e.g., it is not clear why ...

    Authors: Julian K. Christians, Kendra I. Lennie, Lisa K. Wild and Raajan Garcha

    Citation: Reproductive Biology and Endocrinology 2019 17:39

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  6. Content type: Research

    Endometriosis is an estrogen dependent, inflammatory disorder occurring in 5–10% of reproductive-aged women. Women with endometriosis have a lower body mass index (BMI) and decreased body fat compared to those...

    Authors: Masoumeh Majidi Zolbin, Ramanaiah Mamillapalli, Sepide E. Nematian, Laura Goetz and Hugh S. Taylor

    Citation: Reproductive Biology and Endocrinology 2019 17:36

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  7. Content type: Research

    Matrix metalloproteinases (MMPs), especially the gelatinases MMP-2 and MMP-9, play a crucial role in the pathogenesis of endometriosis by enabling invasion. Doxycycline is a well-tolerated antibiotic and a pot...

    Authors: Eleftherios P. Samartzis, Daniel Fink, Manuel Stucki and Patrick Imesch

    Citation: Reproductive Biology and Endocrinology 2019 17:38

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  8. Content type: Research

    Ovarian hyperstimulation syndrome (OHSS) is a common and severe complication for patients undergoing IVF/ICSI-ET. Melatonin widely participates in the regulation of female reproductive endocrine activity. Howe...

    Authors: Yiran Li, Lanlan Fang, Yiping Yu, Hao Shi, Sijia Wang, Yanjie Guo and Yingpu Sun

    Citation: Reproductive Biology and Endocrinology 2019 17:37

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  9. Content type: Research

    Serum Antimüllerian hormone (AMH) has been shown to predict various in vitro fertilization (IVF) outcomes. AMH and progesterone (P) are products of granulosa cells of the ovary. Since overall granulosa cell nu...

    Authors: Shahryar K. Kavoussi, Shu-Hung Chen, Caitlin L. Hunn, Brady T. West, John David Wininger, Keikhosrow M. Kavoussi and Parviz K. Kavoussi

    Citation: Reproductive Biology and Endocrinology 2019 17:35

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  10. Content type: Research

    Women with Polycystic Ovary Syndrome (PCOS) present a heterogeneous reproductive and metabolic profile with an increased lifetime risk of Type 2 Diabetes (T2D). Early biomarkers of these metabolic disturbances...

    Authors: Pernille Bækgaard Udesen, Anja Elaine Sørensen, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Marie Louise Muff Wissing, Anne-Lis Mikkelsen Englund and Louise Torp Dalgaard

    Citation: Reproductive Biology and Endocrinology 2019 17:34

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  11. Content type: Research

    The fibrinolytic system and its inhibitors play a number of roles, apart from their function in blood haemostasis and thrombosis, namely in ovarian folliculogenesis and in ovulation. Plasminogen is converted t...

    Authors: Genia F. Burchall, Dodie S. Pouniotis, Helena J. Teede, Sanjeeva Ranasinha, Kirsty A. Walters and Terrence J. Piva

    Citation: Reproductive Biology and Endocrinology 2019 17:33

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  12. Content type: Research

    A predominant difference between endometrial and normal cells is higher proliferation rate in the former cells which is benign. The genes of inhibitor of differentiation (ID) family play a major role in cell prol...

    Authors: Shirin Amirteimouri, Manan Ashini, Fariba Ramazanali, Reza Aflatoonian, Parvaneh Afsharian and Maryam Shahhoseini

    Citation: Reproductive Biology and Endocrinology 2019 17:32

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  13. Content type: Correction

    .

    Authors: Alessandro Conforti, Sandro C. Esteves, Francesca Di Rella, Ida Strina, Pasquale De Rosa, Alessia Fiorenza, Fulvio Zullo, Giuseppe De Placido and Carlo Alviggi

    Citation: Reproductive Biology and Endocrinology 2019 17:31

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    The original article was published in Reproductive Biology and Endocrinology 2019 17:18

  14. Content type: Research

    In order to maximize In vitro fertilization (IVF) success rates in advanced- age patients, it has been suggested to favor the use of intracytoplasmic sperm injection (ICSI) over conventional insemination (CI),...

    Authors: Jacob Farhi, Kfir Cohen, Yossi Mizrachi, Ariel Weissman, Arieh Raziel and Raoul Orvieto

    Citation: Reproductive Biology and Endocrinology 2019 17:30

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  15. Content type: Research

    Proteomic studies of follicular fluid (FF) exist for several species, including the horse; however, the seasonal influence on FF proteome has not been explored in livestock. The application of high-throughput ...

    Authors: G. A. Dutra, G. M. Ishak, O. Pechanova, T. Pechan, D. G. Peterson, J. C. F. Jacob, S. T. Willard, P. L. Ryan, E. L. Gastal and J. M. Feugang

    Citation: Reproductive Biology and Endocrinology 2019 17:29

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  16. Content type: Research

    Syndecan-1 is a heparan sulfate proteoglycan acting as a co-receptor for cytokines and growth factors mediating developmental, immunological and angiogenic processes. In human, the uteroplacental localization ...

    Authors: Christina Gougoula, Alexandra P. Bielfeld, Sarah J. Pour, Jan-S. Krüssel, Martin Götte, W. Peter M. Benten and Dunja M. Baston-Büst

    Citation: Reproductive Biology and Endocrinology 2019 17:28

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  17. Content type: Research

    Some studies have suggested that blastocyst transfer is associated with i) imbalance in the secondary sex ratio (SSR) (which favors male offspring), ii) increased incidence of monozygotic twins (MZT). In contr...

    Authors: Hiromitsu Hattori, Akane Kitamura, Fumiaki Takahashi, Norio Kobayashi, Akiko Sato, Naoko Miyauchi, Hidekazu Nishigori, Satoshi Mizuno, Kasumi Sakurai, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Shinichi Kuriyama, Hirohito Metoki…

    Citation: Reproductive Biology and Endocrinology 2019 17:27

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  18. Content type: Research

    Hormonal contraceptives, particularly depot medroxyprogesterone acetate (DMPA), have been reported to be associated with substantially enhanced HIV acquisition; however, the biological mechanisms of this risk ...

    Authors: Liping Li, Jie Zhou, Weijia Wang, Lina Huang, Jiaoqin Tu, Lyndsey Baiamonte, Moselle Stark, Mistie Mills, Thomas J. Hope, Erma Z. Drobnis, Alison J. Quayle and Danny J. Schust

    Citation: Reproductive Biology and Endocrinology 2019 17:26

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  19. Content type: Research

    In dairy cows, the energy cost of milk yield results in a negative energy balance (EB) and body fat mobilization that impairs reproductive efficiency. Emerging evidence suggests that the novel adipokines, Reti...

    Authors: Namya Mellouk, Christelle Ramé, Mélodie Diot, Eric Briant, Jean-Luc Touzé, Daniel Guillaume, Pascal Froment and Joëlle Dupont

    Citation: Reproductive Biology and Endocrinology 2019 17:25

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  20. Content type: Research

    Infertile men have higher levels of semen reactive oxygen species (ROS) than fertile men. High levels of semen ROS can cause sperm dysfunction, sperm DNA damage and reduced male reproductive potential. This st...

    Authors: Rahil Jannatifar, Kazem Parivar, Nasim Hayati Roodbari and Mohammad Hossein Nasr-Esfahani

    Citation: Reproductive Biology and Endocrinology 2019 17:24

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  21. Content type: Research

    Age-associated infertility is a problem worldwide, and management of oxidative stress is known to be essential. Nuclear factor-E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-antioxidant...

    Authors: Nana Akino, Osamu Wada-Hiraike, Wataru Isono, Hiromi Terao, Harunori Honjo, Yuichiro Miyamoto, Michihiro Tanikawa, Kenbun Sone, Mana Hirano, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Kaori Koga, Katsutoshi Oda, Tomoyuki Fujii and Yutaka Osuga

    Citation: Reproductive Biology and Endocrinology 2019 17:23

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  22. Content type: Research

    Previous studies, which were primarily based on the fluorescent in-situ hybridisation (FISH) technique, revealed conflicting evidence regarding male foetal microchimerism in endometriosis. FISH is a relatively...

    Authors: Muzaffer A. Bhat, Jai B. Sharma, Kallol K. Roy, Jayasree Sengupta and Debabrata Ghosh

    Citation: Reproductive Biology and Endocrinology 2019 17:22

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  23. Content type: Research

    Endometriosis is thought to affect the effectiveness of ART by an increased risk of miscarriage. We aimed to investigate the impact of endometriosis in women achieving singleton pregnancies through IVF fresh c...

    Authors: Puyu Yang, Yang Wang, Zhangxin Wu, Ningning Pan, Liying Yan and Caihong Ma

    Citation: Reproductive Biology and Endocrinology 2019 17:21

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  24. Content type: Research

    Despite being born with a significant number of primordial cells which representing the ancestor cells of the germ-line, women experience a depletion of ovarian reserve and sub-fertility mid-way into their hea...

    Authors: Haroon Latif Khan, Shahzad Bhatti, Samina Suhail, Rohina Gul, Aisha Awais, Humaira Hamayun, Farah Enver, Sana Abbas, Zahira Hassan, Rameen Nisar, Saba Sardar and Warda Asif

    Citation: Reproductive Biology and Endocrinology 2019 17:20

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  25. Content type: Research

    Steroidogenesis is an indispensable process that is indirectly associated with spermatogenesis in the Leydig cell (LC) to utilize the lipid droplets (LDs) that are critical to maintaining normal testosterone s...

    Authors: Imran Tarique, Waseem Ali Vistro, Xuebing Bai, Ping Yang, Chen Hong, Yufei Huang, Abdul Haseeb, Enxue Liu, Noor Samad Gandahi, Mengdi Xu, Yifei Liu and Qiusheng Chen

    Citation: Reproductive Biology and Endocrinology 2019 17:19

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  26. Content type: Review

    To study the role of recombinant human LH supplementation in women with hypo-response to ovarian stimulation.

    Authors: Alessandro Conforti, Sandro C. Esteves, Francesca Di Rella, Ida Strina, Pasquale De Rosa, Alessia Fiorenza, Fulvio Zullo, Giuseppe De Placido and Carlo Alviggi

    Citation: Reproductive Biology and Endocrinology 2019 17:18

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    The Correction to this article has been published in Reproductive Biology and Endocrinology 2019 17:31

  27. Content type: Review

    The objective of this systematic review was to examine the literature and to compare the effectiveness of letrozole (LE) versus laparoscopic ovarian drilling (LOD) for the induction of ovulation in women with ...

    Authors: Qiong Yu, Shifu Hu, Yingying Wang, Guiping Cheng, Wei Xia and Changhong Zhu

    Citation: Reproductive Biology and Endocrinology 2019 17:17

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  28. Content type: Research

    Little is known about resident attitudes toward elective egg freezing (EF) or how educational exposure to EF affects residents’ views and ability to counsel patients. This study aimed to evaluate US OB/GYN res...

    Authors: Navid Esfandiari, Julia Litzky, Joshua Sayler, Pavel Zagadailov, Karen George and Leslie DeMars

    Citation: Reproductive Biology and Endocrinology 2019 17:16

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  29. Content type: Research

    To assess the predictive value of each individual morphological parameter: blastocoele expansion degree, inner cell mass (ICM), and trophectoderm (TE) grades on the clinical pregnancy outcome in frozen–warmed ...

    Authors: Jing Zhao, Yi Yan, Xi Huang, Lunquan Sun and Yanping Li

    Citation: Reproductive Biology and Endocrinology 2019 17:15

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  30. Content type: Research

    Intrauterine insemination (IUI) is the first-line treatment for non-tubal infertility. Injectable gonadotropins are often chosen as adjunctive stimulation to promote the growth of ovarian follicles in IUI cycl...

    Authors: Yiwen Liu, Xiang Y. Ye and Crystal Chan

    Citation: Reproductive Biology and Endocrinology 2019 17:14

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  31. Content type: Research

    Excessive gestational weight gain (GWG), which is associated with adverse long-term effects on the health of the offspring, has become a major clinical problem. Accumulating evidence indicates that the ovary k...

    Authors: Zhiyang Zhou, Qi Lin, Xinxin Xu, Gaby Sukma Illahi, Chenle Dong and Xueqing Wu

    Citation: Reproductive Biology and Endocrinology 2019 17:13

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  32. Content type: Review

    Among the factors causing male infertility, one of the most debated is the exposure to environmental contaminants. Recently, the chemical compound Bisphenol A (BPA) has drawn attention from the reproductive sc...

    Authors: Federica Cariati, Nadja D’Uonno, Francesca Borrillo, Stefania Iervolino, Giacomo Galdiero and Rossella Tomaiuolo

    Citation: Reproductive Biology and Endocrinology 2019 17:6

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  33. Content type: Research

    Detrimental exposures during pregnancy have been implicated in programming offspring to develop permanent changes in physiology and metabolism, increasing the risk for developing diseases in adulthood such as ...

    Authors: Amy K. Schutt, Chellakkan S. Blesson, Jean W. Hsu, Cecilia T. Valdes, William E. Gibbons, Farook Jahoor and Chandra Yallampalli

    Citation: Reproductive Biology and Endocrinology 2019 17:12

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  34. Content type: Review

    A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that co...

    Authors: Justin Rashtian, Diana E. Chavkin and Zaher Merhi

    Citation: Reproductive Biology and Endocrinology 2019 17:5

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  35. Content type: Research

    In assisted reproductive technology, prediction of treatment failure remains a great challenge. The development of more sensitive assays for measuring anti-Müllerian hormone (AMH) has allowed for the possibili...

    Authors: A. G. Grynnerup, K. Løssl, F. Pilsgaard, S. A. Lunding, M. Storgaard, J. W. Bogstad, L. Prætorius, A. Zedeler, L. Bungum, A. Nyboe Andersen and A. Pinborg

    Citation: Reproductive Biology and Endocrinology 2019 17:11

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  36. Content type: Research

    A low oxygen supply to the fetus causes intrauterine growth restriction and can affect gonadal development of the offspring, having a potential impact on fertility. We investigated histology and gene expressio...

    Authors: Valentina Pampanini, Kirsi Jahnukainen, Lena Sahlin, Daniela Germani, Antonella Puglianiello, Stefano Cianfarani and Olle Söder

    Citation: Reproductive Biology and Endocrinology 2019 17:10

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  37. Content type: Review

    MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of miRNAs in ovarian development a...

    Authors: Jinbi Zhang, Yinxue Xu, Honglin Liu and Zengxiang Pan

    Citation: Reproductive Biology and Endocrinology 2019 17:9

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  38. Content type: Review

    Over the past two decades, public health has focused on the identification of environmental chemical factors that are able to adversely affect hormonal function, known as endocrine disruptors (EDs). EDs mimic ...

    Authors: Andrea Di Nisio and Carlo Foresta

    Citation: Reproductive Biology and Endocrinology 2019 17:4

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  39. Content type: Review

    A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordi...

    Authors: Bo Pan and Julang Li

    Citation: Reproductive Biology and Endocrinology 2019 17:8

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  40. Content type: Research

    Diminished ovarian reserve (DOR) remains one of the greatest obstacles affecting the chance of a successful live birth after fertility treatment. The present study was set to investigate whether using a “dual ...

    Authors: Ming-Huei Lin, Frank Shao-Ying Wu, Yuh-Ming Hwu, Robert Kuo-Kuang Lee, Ryh-Sheng Li and Sheng-Hsiang Li

    Citation: Reproductive Biology and Endocrinology 2019 17:7

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  41. Content type: Research

    Fertility preservation (FP) protocols in case of breast cancer (BC) include mature oocyte cryopreservation following letrozole associated controlled ovarian hyperstimulation (Let-COH). To date, the impact of L...

    Authors: Oranite Goldrat, Geraldine Van Den Steen, Eric Gonzalez-Merino, Julie Dechène, Christine Gervy, Anne Delbaere, Fabienne Devreker, Viviane De Maertelaer and Isabelle Demeestere

    Citation: Reproductive Biology and Endocrinology 2019 17:3

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  42. Content type: Research

    Chronic endometritis (CE) is a condition which results in reduced receptivity of embryos by dysregulated lymphocyte subsets, abnormal expression of cytokines, chemokines and other regulatory molecules in the e...

    Authors: Wen-juan Wang, Hong Zhang, Zhong-quan Chen, Wei Zhang, Xue-mei Liu, Jiang-ye Fang, Fu-jun Liu and Joanne Kwak-Kim

    Citation: Reproductive Biology and Endocrinology 2019 17:2

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  43. Content type: Research

    Melatonin is an amine hormone that plays an important role in regulating mammalian reproduction. This study aimed to investigate the expression pattern of melatonin synthesis enzymes AANAT and HIOMT and melato...

    Authors: Longfei Xiao, Junjie Hu, Liangli Song, Yong Zhang, Weitao Dong, Yuting Jiang, Quanwei Zhang, Ligang Yuan and Xingxu Zhao

    Citation: Reproductive Biology and Endocrinology 2019 17:1

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  44. Content type: Review

    Air pollution is a cause of concern for human health. For instance, it is associated with an increased risk for cancer, cardiovascular and respiratory disorders. In vitro and in vivo studies suggested that air...

    Authors: Alessandro Conforti, Marika Mascia, Giuseppina Cioffi, Cristina De Angelis, Giuseppe Coppola, Pasquale De Rosa, Rosario Pivonello, Carlo Alviggi and Giuseppe De Placido

    Citation: Reproductive Biology and Endocrinology 2018 16:117

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  45. Content type: Research

    Recently, a novel approach with delaying the start of controlled ovarian stimulation along with gonadotropin-releasing hormone (GnRH) antagonist pretreatment for 7 days after estrogen priming for further suppr...

    Authors: Mahnaz Ashrafi, Arezoo Arabipoor, Azar Yahyaei, Zahra Zolfaghari and Firouzah Ghaffari

    Citation: Reproductive Biology and Endocrinology 2018 16:124

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  46. Content type: Review

    Exposure to air pollution has been clearly associated with a range of adverse health effects, including reproductive toxicity. However, a limited amount of research has been conducted to examine the associatio...

    Authors: Joanna Jurewicz, Emila Dziewirska, Michał Radwan and Wojciech Hanke

    Citation: Reproductive Biology and Endocrinology 2018 16:109

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  47. Content type: Review

    Hundreds of thousands of young women are diagnosed with cancer each year, and due to recent advances in screening programs, diagnostic methods and treatment options, survival rates have significantly improved....

    Authors: Roberto Marci, Maddalena Mallozzi, Luisa Di Benedetto, Mauro Schimberni, Stefano Mossa, Ilaria Soave, Stefano Palomba and Donatella Caserta

    Citation: Reproductive Biology and Endocrinology 2018 16:112

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  48. Content type: Review

    During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense expos...

    Authors: Kavindra Kumar Kesari, Ashok Agarwal and Ralf Henkel

    Citation: Reproductive Biology and Endocrinology 2018 16:118

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  49. Content type: Review

    The objective of this study was to carry out a systematic review and meta-analysis of embryologic and clinical outcomes following open versus closed vitrification of human oocytes and embryos.

    Authors: Hongcai Cai, Jean Damascene Niringiyumukiza, Yamin Li, Qiaohong Lai, Yinzhao Jia, Ping Su and Wenpei Xiang

    Citation: Reproductive Biology and Endocrinology 2018 16:123

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