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  1. Thyroid autoimmunity (TAI) – the presence of anti-thyroid peroxidase and/or anti-thyroglobulin antibodies – affects 8–14% of reproductively-aged women. It is hotly debated whether TAI adversely affects IVF/ICS...

    Authors: Ashley Venables, Wilbert Wong, Mandy Way and Hayden Anthony Homer

    Citation: Reproductive Biology and Endocrinology 2020 18:120

    Content type: Review

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  2. Endometriosis is a benign gynecological disease with obviously feature of estrogen-dependence and inflammatory response. The applications of primary endometriotic stromal cells in research of endometriosis are...

    Authors: Zhi-Xiong Huang, Rong-Feng Wu, Xiao-Mei Mao, Shao-Min Huang, Tian-Tian Liu, Qiong-Hua Chen and Qing-Xi Chen

    Citation: Reproductive Biology and Endocrinology 2020 18:119

    Content type: Research

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  3. High anti-Müllerian hormone (AMH) levels and 25-hydroxyvitamin D [25(OH)D] deficiency have been associated with polycystic ovarian syndrome (PCOS) in adult women, and implicated in its pathogenesis. Herein we ...

    Authors: Samantha Simpson, David B. Seifer, Veronika Shabanova, Anna Y. Lynn, Catherine Howe, Erin Rowe, Sonia Caprio and Alla Vash-Margita

    Citation: Reproductive Biology and Endocrinology 2020 18:118

    Content type: Research

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  4. Solute carrier family 2 member 1 (SLC2A1; previously known as glucose transporter 1), is the most abundant glucose transporter in human endometrium and is up-regulated during decidualization, whereas high insu...

    Authors: Ivika Jakson, Dorina Ujvari, Sebastian Brusell Gidlöf and Angelica Lindén Hirschberg

    Citation: Reproductive Biology and Endocrinology 2020 18:117

    Content type: Research

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  5. Endometriosis is an estrogen-dependent inflammatory disease that often causes infertility and chronic pelvic pain. Although endometriosis is known as a benign disease, it has demonstrated characteristics of ma...

    Authors: Ceyda Sancakli Usta, Gulay Turan, Cagla Bahar Bulbul, Akin Usta and Ertan Adali

    Citation: Reproductive Biology and Endocrinology 2020 18:116

    Content type: Research

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  6. Considering that clinical trial studies are limited in polycystic ovary syndrome (PCOS) patients, and there is no consensus on an optimum endometrial preparation protocol for frozen embryo transfer (FET), the ...

    Authors: Azadeh Hosseini-Najarkolaei, Ashraf Moini, Ladan Kashani, Maryam Farid Mojtahedi, Elnaz Hosseini-Najarkolaee and Ensieh Salehi

    Citation: Reproductive Biology and Endocrinology 2020 18:115

    Content type: Research

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  7. Etiology of polycystic ovary syndrome (PCOS) is attributed to genetic and environmental factors. One environmental factor is oxidative stress. Paraoxonase 1 (PON1) is an antioxidant high-density lipoprotein-as...

    Authors: Anthicha Kunjantarachot, Noel Pabalan, Hamdi Jarjanazi, Denise Maria Christofolini, Erik Montagna, Caio Parente Barbosa and Bianca Bianco

    Citation: Reproductive Biology and Endocrinology 2020 18:114

    Content type: Research

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  8. Numerous studies have demonstrated substantial differences in assisted reproductive technology outcomes between black non-Hispanic and white non-Hispanic women. We sought to determine if disparities in assiste...

    Authors: D. B. Seifer, B. Simsek, E. Wantman and A. M. Kotlyar

    Citation: Reproductive Biology and Endocrinology 2020 18:113

    Content type: Research

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  9. Antioxidant/oxidant imbalance has been reported to be related to diminished ovarian reserve (DOR). Vitamin A (retinol), a kind of antioxidant, plays a role in restoring ovarian oxidative damage, while C-reacti...

    Authors: Wen Zou, Zehao Wang, Jing Xia and Jing Yang

    Citation: Reproductive Biology and Endocrinology 2020 18:111

    Content type: Research

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  10. Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. ...

    Authors: Iman Halvaei, Julia Litzky and Navid Esfandiari

    Citation: Reproductive Biology and Endocrinology 2020 18:110

    Content type: Review

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  11. To investigate the long-term effect of prenatal exposure to earthquake stress on diabetes risk in the adulthood.

    Authors: Na Li, Mei Song, Lan Wang, Xiao-chuan Zhao, Ran Wang, Yuan-yuan Gao, Lu-lu Yu, Cui-xia An and Xue-yi Wang

    Citation: Reproductive Biology and Endocrinology 2020 18:109

    Content type: Research

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  12. Previous caesarean scar pregnancy is one type of ectopic pregnancy in myometrium and fibrous tissue of previous caesarean scar. One of the therapeutic methods of this type of ectopic pregnancy is treatment wit...

    Authors: Nader Salari, Mohsen Kazeminia, Shamarina Shohaimi, Anis al-Dawlah Nankali and Masoud Mohammadi

    Citation: Reproductive Biology and Endocrinology 2020 18:108

    Content type: Research

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  13. Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) is a severe autoimmune neurological disorder, and the influence of teratoma-induced autoantibodies on the pathogenesis rema...

    Authors: Xiaoya Zhao, Juan Li, Qian Zhu, Guiling Liang, Wei Xia, Xiaoqing He, Chenfeng Zhu, Hang Qi, Bo Deng, Xiangjun Chen and Jian Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:107

    Content type: Research

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  14. Prenatal testosterone (T) excess results in reproductive and metabolic perturbations in female sheep that closely recapitulate those seen in women with polycystic ovary syndrome (PCOS). At the neuroendocrine l...

    Authors: Renata S. M. Landers, Vasantha Padmanabhan and Rodolfo C. Cardoso

    Citation: Reproductive Biology and Endocrinology 2020 18:106

    Content type: Research

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  15. A member of the newly discovered RNA family, circular RNA (circRNA) is considered as the intermediate product of by-product splicing or abnormal RNA splicing. With the development of RNA sequencing, circRNA ha...

    Authors: Yalan Ma, Ying Xu, Jingshun Zhang and Lianwen Zheng

    Citation: Reproductive Biology and Endocrinology 2020 18:104

    Content type: Review

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  16. Patients found to be poor ovarian responders (POR) are a challenging patient population for any assisted reproduction technology. Despite attempts at various controlled ovarian stimulation schemes, reproductiv...

    Authors: Yanqun Luo, Li Sun, Mei Dong, Xiqian Zhang, Li Huang, Xiulan Zhu, Yingqi Nong and Fenghua Liu

    Citation: Reproductive Biology and Endocrinology 2020 18:102

    Content type: Research

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  17. Psychological stress can cause adverse health effects in animals and humans. Accumulating evidence suggests that psychological stress in female mice is associated with ovarian developmental abnormalities accom...

    Authors: Qiu-Yue Zhai, Jun-Jie Wang, Yu Tian, Xiaofang Liu and Zhenhua Song

    Citation: Reproductive Biology and Endocrinology 2020 18:101

    Content type: Review

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  18. Trophoblast cells are required for the establishment of pregnancy and fetal development. Apoptosis is an essential feature for trophoblast invasion. Uncontrolled trophoblast apoptosis is related to some compli...

    Authors: Bin He, Qi Yue Li, Yuan Yuan Wu, Jing Ling Ruan, Xiao Ming Teng, Da Jin Li and Chuan Ling Tang

    Citation: Reproductive Biology and Endocrinology 2020 18:100

    Content type: Research

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  19. The toxic effects of ionizing radiation on the gonads have been widely recognized. Sphingosine 1-phosphate (S1P) has a protective effect on ovarian injury, and although it is known that mitochondria are involv...

    Authors: Jiahui Zhao, Shuyun Zhang, Liesong Chen, Xiaolong Liu, Haihong Su, Lili Chen, Li Yang and Hong Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:99

    Content type: Research

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  20. Human embryogenesis frequently coinciding with cell division mistakes contributing to pervasive embryonic aneuploidy/mosaicism. While embryo self-correction was elegantly demonstrated in mouse models, human st...

    Authors: Raoul Orvieto, Chen Shimon, Shlomit Rienstein, Anat Jonish-Grossman, Hagit Shani and Adva Aizer

    Citation: Reproductive Biology and Endocrinology 2020 18:98

    Content type: Research

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  21. While single embryo transfer (SET) is widely advocated, double embryo transfer (DET) remains preferable in clinical practice to improve IVF success rate, especially in poor prognosis patients with only poor qu...

    Authors: Wenjie Wang, Jiali Cai, Lanlan Liu, Yingpei Xu, Zhenfang Liu, Jinghua Chen, Xiaoming Jiang, Xiaohua Sun and Jianzhi Ren

    Citation: Reproductive Biology and Endocrinology 2020 18:97

    Content type: Research

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  22. The current evidence on the association between obesity-associated markers and semen quality, serum reproductive hormones and lipids remains inconsistent. In this study, we tested the hypothesis that, in infer...

    Authors: Jian-Xiong Ma, Bin Wang, Hai-Song Li, Xue-Juan Jiang, Jia Yu, Cai-Fei Ding and Wang-Qiang Chen

    Citation: Reproductive Biology and Endocrinology 2020 18:95

    Content type: Research

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  23. This study investigated the expression of angiopoietin-like protein 2 (ANGPTL2) in the tissues of rat models of polycystic ovary syndrome (PCOS) and its correlation with PCOS.

    Authors: Dandan Wang, Yihong Guo, Shujuan Chai, Ke Shen, Yanchun Li and Ruiqin Zhao

    Citation: Reproductive Biology and Endocrinology 2020 18:94

    Content type: Research

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  24. One of the possible male sterility risk factors are polymorphisms of Methylenetetrahydrofolate reductase (MTHFR). However, the epidemiologic investigations described inconsistent results regarding MTHFR polymorph...

    Authors: Fereshteh Aliakbari, Farkhondeh Pouresmaeili, Nahal Eshghifar, Zahra Zolghadr and Faezeh Azizi

    Citation: Reproductive Biology and Endocrinology 2020 18:93

    Content type: Review

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  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhaojuan Hou, Qiong Zhang, Jing Zhao, Aizhuang Xu, Aihua He, Xi Huang, Shi Xie, Jing Fu, Lan Xiao and Yanping Li

    Citation: Reproductive Biology and Endocrinology 2020 18:92

    Content type: Correction

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    The original article was published in Reproductive Biology and Endocrinology 2019 17:74

  26. Oxidative stress (OS), defined as an imbalance between excessive reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) production and antioxidant insufficiency, has been suggested to be involved...

    Authors: Yan Gong, Kun Zhang, Dongsheng Xiong, Jiajing Wei, Hao Tan and Shengfang Qin

    Citation: Reproductive Biology and Endocrinology 2020 18:91

    Content type: Research

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  27. Microdissection testicular sperm extraction (microTESE) in men with non-obstructive azoospermia (NOA) is the procedure that results in the highest number of sperm cells retrieved for in vitro fertilization (IV...

    Authors: Parviz K. Kavoussi, Brady T. West, Shu-Hung Chen, Caitlin Hunn, Melissa S. Gilkey, G. Luke Machen, Keikhosrow M. Kavoussi, Amy Esqueda, J. David Wininger and Shahryar K. Kavoussi

    Citation: Reproductive Biology and Endocrinology 2020 18:90

    Content type: Research

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  28. Successful implantation and delivery require both the functional embryo and receptive endometrium in assisted reproductive technology (ART) cycles. However, little is known about embryo-endometrial interaction...

    Authors: Hong Lv, Xiuzhu Li, Jiangbo Du, Xiufeng Ling, Feiyang Diao, Qun Lu, Shiyao Tao, Lei Huang, Shiyao Chen, Xiumei Han, Kun Zhou, Bo Xu, Xiaoyu Liu, Hongxia Ma, Yankai Xia, Hongbing Shen…

    Citation: Reproductive Biology and Endocrinology 2020 18:89

    Content type: Research

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  29. Recently a novel method based on horizontal sperm migration in injection dishes has been introduced as an additional tool for preparation of semen sample in assisted reproductive technology (ART) procedures. I...

    Authors: Domenico Baldini, Annamaria Baldini, Erica Silvestris, Giovanni Vizziello, Daniele Ferri and Damiano Vizziello

    Citation: Reproductive Biology and Endocrinology 2020 18:88

    Content type: Research

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  30. Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation. We used various inhibitors of Ca2+ channels located on t...

    Authors: Feng Wang, Ang Li, Tie-Gang Meng, Le-Yun Wang, Li-Juan Wang, Yi Hou, Heide Schatten, Qing-Yuan Sun and Xiang-Hong Ou

    Citation: Reproductive Biology and Endocrinology 2020 18:87

    Content type: Research

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  31. There is a need for a reference material to support the development and ensure the quality of immunoassays for human AMH. A batch of ampoules, coded 16/190, containing lyophilised recombinant AMH was evaluated...

    Authors: Jackie Ferguson, Jason Hockley, Peter Rigsby and Chris Burns

    Citation: Reproductive Biology and Endocrinology 2020 18:86

    Content type: Research

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  32. There is a growing body of evidence on low serum vitamin-D levels and the risk of uterine leiomyomas (UL). Therefore, this systematic review and meta-analysis was conducted to investigate the association betwe...

    Authors: Ramin Mohammadi, Reza Tabrizi, Kamran Hessami, Hoda Ashari, Peyman Nowrouzi-Sohrabi, Mahnaz Hosseini-Bensenjan and Nasrin Asadi

    Citation: Reproductive Biology and Endocrinology 2020 18:85

    Content type: Review

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  33. Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cyc...

    Authors: Palak Gujral, Vishakha Mahajan, Abbey C. Lissaman and Anna P. Ponnampalam

    Citation: Reproductive Biology and Endocrinology 2020 18:84

    Content type: Review

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  34. Previous studies have shown that there is an association between FMR1 CGG repeats and ovarian dysfunction. The aim of this study is to assess the association between the number of CGG repeats in FMR1 in Chinese p...

    Authors: Ruiyi Tang and Qi Yu

    Citation: Reproductive Biology and Endocrinology 2020 18:82

    Content type: Research

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  35. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in reproductive-aged women. It is reported that intrauterine exposure to hyperandrogenism may induce the development of PCOS and a...

    Authors: Changling Duan, Tianjiao Pei, Yujing Li, Qi Cao, Hanxiao Chen and Jing Fu

    Citation: Reproductive Biology and Endocrinology 2020 18:81

    Content type: Review

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  36. Chromosomal inversion was considered to have adverse effects on pregnancy outcomes through abnormal gametogenesis. The purpose of this retrospective study was to investigate whether preimplantation genetic tes...

    Authors: Yuhan Shao, Jing Li, Juanjuan Lu, Hongchang Li, Yueting Zhu, Wenjie Jiang and Junhao Yan

    Citation: Reproductive Biology and Endocrinology 2020 18:79

    Content type: Research

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  37. Premature Ovarian Insufficiency (POI) is viewed as a type of infertility in which the menopausal status occurs before the physiological age. Several therapeutic strategies have been introduced in clinic for PO...

    Authors: Shahin Ahmadian, Sepideh Sheshpari, Mohammad Pazhang, Alberto Miranda Bedate, Rahim Beheshti, Mehran Mesgari Abbasi, Mohammad Nouri, Reza Rahbarghazi and Mahdi Mahdipour

    Citation: Reproductive Biology and Endocrinology 2020 18:78

    Content type: Research

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  38. Sheep are important livestock with variant ovulation rate and fertility. Dorset sheep is a typical breed with low prolificacy, whereas Small Tail Han sheep with FecB mutation (HanBB) have hyperprolificacy. Our...

    Authors: Xiangyang Miao, Qingmiao Luo, Lingli Xie, Huijing Zhao and Xiaoyu Qin

    Citation: Reproductive Biology and Endocrinology 2020 18:77

    Content type: Research

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  39. The aim of this meta-analysis was to evaluate the effect of growth hormone (GH) supplementation in poor responders undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

    Authors: Peiwen Yang, Ruxing Wu and Hanwang Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:76

    Content type: Review

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  40. Fertility preservation is particularly challenging in young women diagnosed with hematopoietic cancers, as transplantation of cryopreserved ovarian cortex in these women carries the risk for re-introducing can...

    Authors: Ahmed Baker Alshaikh, Arvind Manikantan Padma, Matilda Dehlin, Randa Akouri, Min Jong Song, Mats Brännström and Mats Hellström

    Citation: Reproductive Biology and Endocrinology 2020 18:75

    Content type: Research

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  41. With the rapid development of whole embryo freezing technology, more and more frozen-thawed embryo transfer (FET) was used in assisted reproductive technology. However, the best FET program for elderly women h...

    Authors: Mei Dong, Li Sun, Li Huang, Yanhong Yi, Xiqian Zhang, Ying Tan, Ge Song, Liling Liu, Fu Wei and Fenghua Liu

    Citation: Reproductive Biology and Endocrinology 2020 18:73

    Content type: Research

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  42. To investigate the associations between blastocyst development and the sex ratio (male:female) among singleton live births resulting from single-blastocyst frozen embryo transfer (FET) cycles.

    Authors: Hua Lou, Na Li, Xiaoke Zhang, Ling Sun, Xingling Wang, Dayong Hao and Shihong Cui

    Citation: Reproductive Biology and Endocrinology 2020 18:72

    Content type: Research

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  43. The in vitro maturation (IVM) technique has physical and financial benefits, but a lower efficiency and outcome that is still unclear whether it is related to polycystic ovary syndrome (PCOS) itself or the IVM...

    Authors: Nagwa Elshewy, Dongmei Ji, Zhiguo Zhang, Dawei Chen, Beili Chen, Rufeng Xue, Huan Wu, Jianye Wang, Ping Zhou and Yunxia Cao

    Citation: Reproductive Biology and Endocrinology 2020 18:71

    Content type: Research

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