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  1. To explore the social and psychological factors associated with male Temporary Ejaculation Failure (TEF) during In Vitro Fertilization (IVF), with the goal of providing a theoretical basis for clinical interventi...

    Authors: Jinluan Wang and Mingyue Xue

    Citation: Reproductive Biology and Endocrinology 2021 19:9

    Content type: Research

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  2. Ovarian hyperstimulation syndrome (OHSS) is a common disease during controlled ovarian hyperstimulation treatment. However, the obstetric and neonatal outcomes of this group of patients are unknown. The aim of...

    Authors: Linli Hu, Rui Xie, Mengying Wang and Yingpu Sun

    Citation: Reproductive Biology and Endocrinology 2021 19:8

    Content type: Research

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  3. Adenomyosis (AM) is an important cause of female infertility. However, the underlying mechanism remains unclear. This report describes a preliminary study of hypoxia and its possible association with endometri...

    Authors: Song Guo, Di Zhang, Xiaowei Lu, Qian Zhang, Ruihuan Gu, Binghui Sun and Yijuan Sun

    Citation: Reproductive Biology and Endocrinology 2021 19:7

    Content type: Research

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  4. Women who conceived with in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) are more likely to experience adverse pregnancy outcomes than women who conceived naturally. Cervical insufficie...

    Authors: Yaoqiu Wu, Xiaoyan Liang, Meihong Cai, Linzhi Gao, Jie Lan and Xing Yang

    Citation: Reproductive Biology and Endocrinology 2021 19:6

    Content type: Research

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  5. The etiology between homocysteine and polycystic ovary syndrome (PCOS) is unclear. In humans, the level of homocysteine is mainly affected by two enzymes: methylene tetrahydrofolate reductase (MTHFR) and methi...

    Authors: Wanqin Feng, Yan Zhang, Yuan Pan, Yi Zhang, Minjuan Liu, Yuxin Huang, Yuanling Xiao, Wenyu Mo, Junjie Jiao, Xiaoyang Wang, Dan Tian, Lixia Yang and Ying Ma

    Citation: Reproductive Biology and Endocrinology 2021 19:5

    Content type: Research

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  6. Spermatogenesis is a complex process that is controlled by interactions between germ cells and somatic cells. The commitment of undifferentiated spermatogonia to differentiating spermatogonia and normal sperma...

    Authors: Maryam Khanehzad, Roya Abbaszadeh, Marzieh Holakuyee, Mohammad Hossein Modarressi and Seyed Mehdi Nourashrafeddin

    Citation: Reproductive Biology and Endocrinology 2021 19:4

    Content type: Review

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  7. Polycystic ovary syndrome (PCOS) is a common endocrine disease of the female reproductive system that seriously affects women’s health. Berberine (BBR) has many pharmacological properties and is used as an ins...

    Authors: Hao-Ran Shen, Xiao Xu and Xue-Lian Li

    Citation: Reproductive Biology and Endocrinology 2021 19:3

    Content type: Research

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  8. The establishment of uterine receptivity is essential for embryo implantation initiation and involves a significant morphological transformation in the endometrial epithelial cells (EECs). The remodeling of ju...

    Authors: Jingjie Liang, Kui Li, Kaiyu Chen, Junyong Liang, Ti Qin, Jiayi He, Shuang Shi, Qiang Tan and Zhengguang Wang

    Citation: Reproductive Biology and Endocrinology 2021 19:2

    Content type: Research

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  9. Caloric restriction (CR), an energy-restricted intervention with undernutrition instead of malnutrition, is widely known to prolong lifespan and protect against the age-related deteriorations. Recently it is f...

    Authors: Jiayi Sun, Xin Shen, Hui Liu, Siying Lu, Jing Peng and Haibin Kuang

    Citation: Reproductive Biology and Endocrinology 2021 19:1

    Content type: Review

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  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: David B. Seifer, Burcin Simsek, Ethan Wantman and Alexander M. Kotlyar

    Citation: Reproductive Biology and Endocrinology 2020 18:125

    Content type: Correction

    Published on:

    The original article was published in Reproductive Biology and Endocrinology 2020 18:113

  11. The endometrium undergoes cyclic remodelling throughout the menstrual cycle in preparation for embryo implantation which occurs in a short window during the mid-secretory phase. It is during this short ‘recept...

    Authors: Leilani L. Santos, Cheuk Kwan Ling and Evdokia Dimitriadis

    Citation: Reproductive Biology and Endocrinology 2020 18:124

    Content type: Research

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  12. Whether artificial oocyte activation (ICSI-AOA) will increase the risk of birth defects remains controversial. Thus, we performed this study to evaluate the risk of birth defects and further compare the incide...

    Authors: Rui Long, Meng Wang, Qi Yu Yang, Shi Qiao Hu, Li Xia Zhu and Lei Jin

    Citation: Reproductive Biology and Endocrinology 2020 18:123

    Content type: Review

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  13. Circadian rhythm disruption impacts a wide range of physiological processes, including fertility. However, the effect of circadian disruption on male spermatogenesis and fertility, and treatments for these eff...

    Authors: Yihua Xu, Li Wang, Siyuan Cao, Ruihua Hu, Rui Liu, Ke Hua, Zhigang Guo, Hong-Jie Di and Zhigang Hu

    Citation: Reproductive Biology and Endocrinology 2020 18:122

    Content type: Research

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  14. It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlyin...

    Authors: Yan Gong, Shan Luo, Ping Fan, Huili Zhu, Yujing Li and Wei Huang

    Citation: Reproductive Biology and Endocrinology 2020 18:121

    Content type: Research

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  15. Thyroid autoimmunity (TAI) – the presence of anti-thyroid peroxidase and/or anti-thyroglobulin antibodies – affects 8–14% of reproductively-aged women. It is hotly debated whether TAI adversely affects IVF/ICS...

    Authors: Ashley Venables, Wilbert Wong, Mandy Way and Hayden Anthony Homer

    Citation: Reproductive Biology and Endocrinology 2020 18:120

    Content type: Review

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  16. Endometriosis is a benign gynecological disease with obviously feature of estrogen-dependence and inflammatory response. The applications of primary endometriotic stromal cells in research of endometriosis are...

    Authors: Zhi-Xiong Huang, Rong-Feng Wu, Xiao-Mei Mao, Shao-Min Huang, Tian-Tian Liu, Qiong-Hua Chen and Qing-Xi Chen

    Citation: Reproductive Biology and Endocrinology 2020 18:119

    Content type: Research

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  17. High anti-Müllerian hormone (AMH) levels and 25-hydroxyvitamin D [25(OH)D] deficiency have been associated with polycystic ovarian syndrome (PCOS) in adult women, and implicated in its pathogenesis. Herein we ...

    Authors: Samantha Simpson, David B. Seifer, Veronika Shabanova, Anna Y. Lynn, Catherine Howe, Erin Rowe, Sonia Caprio and Alla Vash-Margita

    Citation: Reproductive Biology and Endocrinology 2020 18:118

    Content type: Research

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  18. Solute carrier family 2 member 1 (SLC2A1; previously known as glucose transporter 1), is the most abundant glucose transporter in human endometrium and is up-regulated during decidualization, whereas high insu...

    Authors: Ivika Jakson, Dorina Ujvari, Sebastian Brusell Gidlöf and Angelica Lindén Hirschberg

    Citation: Reproductive Biology and Endocrinology 2020 18:117

    Content type: Research

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  19. Endometriosis is an estrogen-dependent inflammatory disease that often causes infertility and chronic pelvic pain. Although endometriosis is known as a benign disease, it has demonstrated characteristics of ma...

    Authors: Ceyda Sancakli Usta, Gulay Turan, Cagla Bahar Bulbul, Akin Usta and Ertan Adali

    Citation: Reproductive Biology and Endocrinology 2020 18:116

    Content type: Research

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  20. Considering that clinical trial studies are limited in polycystic ovary syndrome (PCOS) patients, and there is no consensus on an optimum endometrial preparation protocol for frozen embryo transfer (FET), the ...

    Authors: Azadeh Hosseini-Najarkolaei, Ashraf Moini, Ladan Kashani, Maryam Farid Mojtahedi, Elnaz Hosseini-Najarkolaee and Ensieh Salehi

    Citation: Reproductive Biology and Endocrinology 2020 18:115

    Content type: Research

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  21. Etiology of polycystic ovary syndrome (PCOS) is attributed to genetic and environmental factors. One environmental factor is oxidative stress. Paraoxonase 1 (PON1) is an antioxidant high-density lipoprotein-as...

    Authors: Anthicha Kunjantarachot, Noel Pabalan, Hamdi Jarjanazi, Denise Maria Christofolini, Erik Montagna, Caio Parente Barbosa and Bianca Bianco

    Citation: Reproductive Biology and Endocrinology 2020 18:114

    Content type: Research

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  22. Numerous studies have demonstrated substantial differences in assisted reproductive technology outcomes between black non-Hispanic and white non-Hispanic women. We sought to determine if disparities in assiste...

    Authors: David B. Seifer, Burcin Simsek, Ethan Wantman and Alexander M. Kotlyar

    Citation: Reproductive Biology and Endocrinology 2020 18:113

    Content type: Research

    Published on:

    The Correction to this article has been published in Reproductive Biology and Endocrinology 2020 18:125

  23. Antioxidant/oxidant imbalance has been reported to be related to diminished ovarian reserve (DOR). Vitamin A (retinol), a kind of antioxidant, plays a role in restoring ovarian oxidative damage, while C-reacti...

    Authors: Wen Zou, Zehao Wang, Jing Xia and Jing Yang

    Citation: Reproductive Biology and Endocrinology 2020 18:111

    Content type: Research

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  24. Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. ...

    Authors: Iman Halvaei, Julia Litzky and Navid Esfandiari

    Citation: Reproductive Biology and Endocrinology 2020 18:110

    Content type: Review

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  25. To investigate the long-term effect of prenatal exposure to earthquake stress on diabetes risk in the adulthood.

    Authors: Na Li, Mei Song, Lan Wang, Xiao-chuan Zhao, Ran Wang, Yuan-yuan Gao, Lu-lu Yu, Cui-xia An and Xue-yi Wang

    Citation: Reproductive Biology and Endocrinology 2020 18:109

    Content type: Research

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  26. Previous caesarean scar pregnancy is one type of ectopic pregnancy in myometrium and fibrous tissue of previous caesarean scar. One of the therapeutic methods of this type of ectopic pregnancy is treatment wit...

    Authors: Nader Salari, Mohsen Kazeminia, Shamarina Shohaimi, Anis al-Dawlah Nankali and Masoud Mohammadi

    Citation: Reproductive Biology and Endocrinology 2020 18:108

    Content type: Research

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  27. Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) is a severe autoimmune neurological disorder, and the influence of teratoma-induced autoantibodies on the pathogenesis rema...

    Authors: Xiaoya Zhao, Juan Li, Qian Zhu, Guiling Liang, Wei Xia, Xiaoqing He, Chenfeng Zhu, Hang Qi, Bo Deng, Xiangjun Chen and Jian Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:107

    Content type: Research

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  28. Prenatal testosterone (T) excess results in reproductive and metabolic perturbations in female sheep that closely recapitulate those seen in women with polycystic ovary syndrome (PCOS). At the neuroendocrine l...

    Authors: Renata S. M. Landers, Vasantha Padmanabhan and Rodolfo C. Cardoso

    Citation: Reproductive Biology and Endocrinology 2020 18:106

    Content type: Research

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  29. A member of the newly discovered RNA family, circular RNA (circRNA) is considered as the intermediate product of by-product splicing or abnormal RNA splicing. With the development of RNA sequencing, circRNA ha...

    Authors: Yalan Ma, Ying Xu, Jingshun Zhang and Lianwen Zheng

    Citation: Reproductive Biology and Endocrinology 2020 18:104

    Content type: Review

    Published on:

  30. Patients found to be poor ovarian responders (POR) are a challenging patient population for any assisted reproduction technology. Despite attempts at various controlled ovarian stimulation schemes, reproductiv...

    Authors: Yanqun Luo, Li Sun, Mei Dong, Xiqian Zhang, Li Huang, Xiulan Zhu, Yingqi Nong and Fenghua Liu

    Citation: Reproductive Biology and Endocrinology 2020 18:102

    Content type: Research

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  31. Psychological stress can cause adverse health effects in animals and humans. Accumulating evidence suggests that psychological stress in female mice is associated with ovarian developmental abnormalities accom...

    Authors: Qiu-Yue Zhai, Jun-Jie Wang, Yu Tian, Xiaofang Liu and Zhenhua Song

    Citation: Reproductive Biology and Endocrinology 2020 18:101

    Content type: Review

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  32. Trophoblast cells are required for the establishment of pregnancy and fetal development. Apoptosis is an essential feature for trophoblast invasion. Uncontrolled trophoblast apoptosis is related to some compli...

    Authors: Bin He, Qi Yue Li, Yuan Yuan Wu, Jing Ling Ruan, Xiao Ming Teng, Da Jin Li and Chuan Ling Tang

    Citation: Reproductive Biology and Endocrinology 2020 18:100

    Content type: Research

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  33. The toxic effects of ionizing radiation on the gonads have been widely recognized. Sphingosine 1-phosphate (S1P) has a protective effect on ovarian injury, and although it is known that mitochondria are involv...

    Authors: Jiahui Zhao, Shuyun Zhang, Liesong Chen, Xiaolong Liu, Haihong Su, Lili Chen, Li Yang and Hong Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:99

    Content type: Research

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  34. Human embryogenesis frequently coinciding with cell division mistakes contributing to pervasive embryonic aneuploidy/mosaicism. While embryo self-correction was elegantly demonstrated in mouse models, human st...

    Authors: Raoul Orvieto, Chen Shimon, Shlomit Rienstein, Anat Jonish-Grossman, Hagit Shani and Adva Aizer

    Citation: Reproductive Biology and Endocrinology 2020 18:98

    Content type: Research

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  35. While single embryo transfer (SET) is widely advocated, double embryo transfer (DET) remains preferable in clinical practice to improve IVF success rate, especially in poor prognosis patients with only poor qu...

    Authors: Wenjie Wang, Jiali Cai, Lanlan Liu, Yingpei Xu, Zhenfang Liu, Jinghua Chen, Xiaoming Jiang, Xiaohua Sun and Jianzhi Ren

    Citation: Reproductive Biology and Endocrinology 2020 18:97

    Content type: Research

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  36. The current evidence on the association between obesity-associated markers and semen quality, serum reproductive hormones and lipids remains inconsistent. In this study, we tested the hypothesis that, in infer...

    Authors: Jian-Xiong Ma, Bin Wang, Hai-Song Li, Xue-Juan Jiang, Jia Yu, Cai-Fei Ding and Wang-Qiang Chen

    Citation: Reproductive Biology and Endocrinology 2020 18:95

    Content type: Research

    Published on:

  37. This study investigated the expression of angiopoietin-like protein 2 (ANGPTL2) in the tissues of rat models of polycystic ovary syndrome (PCOS) and its correlation with PCOS.

    Authors: Dandan Wang, Yihong Guo, Shujuan Chai, Ke Shen, Yanchun Li and Ruiqin Zhao

    Citation: Reproductive Biology and Endocrinology 2020 18:94

    Content type: Research

    Published on:

  38. One of the possible male sterility risk factors are polymorphisms of Methylenetetrahydrofolate reductase (MTHFR). However, the epidemiologic investigations described inconsistent results regarding MTHFR polymorph...

    Authors: Fereshteh Aliakbari, Farkhondeh Pouresmaeili, Nahal Eshghifar, Zahra Zolghadr and Faezeh Azizi

    Citation: Reproductive Biology and Endocrinology 2020 18:93

    Content type: Review

    Published on:

  39. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhaojuan Hou, Qiong Zhang, Jing Zhao, Aizhuang Xu, Aihua He, Xi Huang, Shi Xie, Jing Fu, Lan Xiao and Yanping Li

    Citation: Reproductive Biology and Endocrinology 2020 18:92

    Content type: Correction

    Published on:

    The original article was published in Reproductive Biology and Endocrinology 2019 17:74

  40. Oxidative stress (OS), defined as an imbalance between excessive reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) production and antioxidant insufficiency, has been suggested to be involved...

    Authors: Yan Gong, Kun Zhang, Dongsheng Xiong, Jiajing Wei, Hao Tan and Shengfang Qin

    Citation: Reproductive Biology and Endocrinology 2020 18:91

    Content type: Research

    Published on:

  41. Microdissection testicular sperm extraction (microTESE) in men with non-obstructive azoospermia (NOA) is the procedure that results in the highest number of sperm cells retrieved for in vitro fertilization (IV...

    Authors: Parviz K. Kavoussi, Brady T. West, Shu-Hung Chen, Caitlin Hunn, Melissa S. Gilkey, G. Luke Machen, Keikhosrow M. Kavoussi, Amy Esqueda, J. David Wininger and Shahryar K. Kavoussi

    Citation: Reproductive Biology and Endocrinology 2020 18:90

    Content type: Research

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  42. Successful implantation and delivery require both the functional embryo and receptive endometrium in assisted reproductive technology (ART) cycles. However, little is known about embryo-endometrial interaction...

    Authors: Hong Lv, Xiuzhu Li, Jiangbo Du, Xiufeng Ling, Feiyang Diao, Qun Lu, Shiyao Tao, Lei Huang, Shiyao Chen, Xiumei Han, Kun Zhou, Bo Xu, Xiaoyu Liu, Hongxia Ma, Yankai Xia, Hongbing Shen…

    Citation: Reproductive Biology and Endocrinology 2020 18:89

    Content type: Research

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  43. Recently a novel method based on horizontal sperm migration in injection dishes has been introduced as an additional tool for preparation of semen sample in assisted reproductive technology (ART) procedures. I...

    Authors: Domenico Baldini, Annamaria Baldini, Erica Silvestris, Giovanni Vizziello, Daniele Ferri and Damiano Vizziello

    Citation: Reproductive Biology and Endocrinology 2020 18:88

    Content type: Research

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  44. Oocyte activation inefficiency is one of the reasons for female infertility and Ca2+ functions play a critical role in the regulation of oocyte activation. We used various inhibitors of Ca2+ channels located on t...

    Authors: Feng Wang, Ang Li, Tie-Gang Meng, Le-Yun Wang, Li-Juan Wang, Yi Hou, Heide Schatten, Qing-Yuan Sun and Xiang-Hong Ou

    Citation: Reproductive Biology and Endocrinology 2020 18:87

    Content type: Research

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  45. There is a need for a reference material to support the development and ensure the quality of immunoassays for human AMH. A batch of ampoules, coded 16/190, containing lyophilised recombinant AMH was evaluated...

    Authors: Jackie Ferguson, Jason Hockley, Peter Rigsby and Chris Burns

    Citation: Reproductive Biology and Endocrinology 2020 18:86

    Content type: Research

    Published on:

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