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  1. Review

    Making gametes from alternate sources of stem cells: past, present and future

    Infertile couples including cancer survivors stand to benefit from gametes differentiated from embryonic or induced pluripotent stem (ES/iPS) cells. It remains challenging to convert human ES/iPS cells into pr...

    Deepa Bhartiya, Sandhya Anand, Hiren Patel and Seema Parte

    Reproductive Biology and Endocrinology 2017 15:89

    Published on: 16 November 2017

  2. Research

    Gene expression profiling of upregulated mRNAs in granulosa cells of bovine ovulatory follicles following stimulation with hCG

    Ovulation and luteinization of follicles are complex biological processes initiated by the preovulatory luteinizing hormone surge. The objective of this study was to identify genes that are differentially expr...

    Jacques G. Lussier, Mame N. Diouf, Valérie Lévesque, Jean Sirois and Kalidou Ndiaye

    Reproductive Biology and Endocrinology 2017 15:88

    Published on: 3 November 2017

  3. Research

    Serum periostin levels in early in pregnancy are significantly altered in women with miscarriage

    Miscarriage is a common complication in pregnancy and there is still a lack of biomarkers usable in asymptomatic patients before the event occurs. Periostin (PER), whose levels rise particularly during injury ...

    A. Freis, J. Schlegel, R. J. Kuon, A. Doster, J. Jauckus, T. Strowitzki and A. Germeyer

    Reproductive Biology and Endocrinology 2017 15:87

    Published on: 2 November 2017

  4. Research

    Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines

    Proper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during ...

    Huimin Xie, Hanne M. Hoffmann, Anita K. Iyer, Melissa J. Brayman, Cindy Ngo, Mary Jean Sunshine and Pamela L. Mellon

    Reproductive Biology and Endocrinology 2017 15:86

    Published on: 24 October 2017

  5. Review

    TGFβ superfamily signaling and uterine decidualization

    Decidualization is an intricate biological process where extensive morphological, functional, and genetic changes take place in endometrial stromal cells to support the development of an implanting blastocyst....

    Nan Ni and Qinglei Li

    Reproductive Biology and Endocrinology 2017 15:84

    Published on: 13 October 2017

  6. Correction

    Reproductive Biology and Endocrinology 2017 15:82

    Published on: 9 October 2017

    The original article was published in Reproductive Biology and Endocrinology 2017 15:72

  7. Research

    Identification of differential genomic DNA Methylation in the hypothalamus of pubertal rat using reduced representation Bisulfite sequencing

    There are many variables affecting the onset of puberty in animals, including genetic, nutritional, and environmental factors. Recent studies suggest that epigenetic regulation, especially DNA methylation, pla...

    Lei Luo, Zhiqiu Yao, Jing Ye, Yuan Tian, Chen Yang, Xiaoxiao Gao, Min Song, Ya Liu, Yunhai Zhang, Yunsheng Li, Xiaorong Zhang and Fugui Fang

    Reproductive Biology and Endocrinology 2017 15:81

    Published on: 6 October 2017

  8. Research

    Effect of day 3 embryo morphometrics and morphokinetics on survival and implantation after slow freezing-thawing and after vitrification-warming: a retrospective cohort study

    Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have be...

    Elia Fernandez Gallardo, Carl Spiessens, Thomas D’Hooghe and Sophie Debrock

    Reproductive Biology and Endocrinology 2017 15:79

    Published on: 3 October 2017

  9. Review

    Ooplasmic transfer in human oocytes: efficacy and concerns in assisted reproduction

    Ooplasmic transfer (OT) technique or cytoplasmic transfer is an emerging technique with relative success, having a significant status in assisted reproduction. This technique had effectively paved the way to a...

    Sara Darbandi, Mahsa Darbandi, Hamid Reza Khorram Khorshid, Mohammad Reza Sadeghi, Ashok Agarwal, Pallav Sengupta, Safaa Al-Hasani and Mohammad Mehdi Akhondi

    Reproductive Biology and Endocrinology 2017 15:77

    Published on: 2 October 2017

  10. Research

    Effects of melatonin administration on embryo implantation and offspring growth in mice under different schedules of photoperiodic exposure

    Embryo implantation is crucial for animal reproduction. Unsuccessful embryo implantation leads to pregnancy failure, especially in human-assisted conception. Environmental factors have a profound impact on emb...

    Lu Zhang, Zhenzhen Zhang, Feng Wang, Xiuzhi Tian, Pengyun Ji and Guoshi Liu

    Reproductive Biology and Endocrinology 2017 15:78

    Published on: 2 October 2017

  11. Research

    Effect of local endometrial injury in proliferative vs. luteal phase on IVF outcomes in unselected subfertile women undergoing in vitro fertilization

    Mechanical endometrial injury prior to IVF has been suggested as a means to increase implantation rates by improving endometrial receptivity. However, the effects of endometrial injury in proliferative vs. lut...

    Wenjie Liu, Reshef Tal, He Chao, Minghui Liu and Ying Liu

    Reproductive Biology and Endocrinology 2017 15:75

    Published on: 22 September 2017

  12. Research

    In vitro progesterone production by luteinized human mural granulosa cells is modulated by activation of AMPK and cause of infertility

    Mural granulosa cells from IVF patients were provided by the West Virginia University Center for Reproductive Medicine in Morgantown, WV. The effect of adenosine monophosphate activated protein kinase (AMPK) a...

    E. C. Bowdridge, M. W. Vernon, J. A. Flores and M. J. Clemmer

    Reproductive Biology and Endocrinology 2017 15:76

    Published on: 22 September 2017

  13. Research

    A new insight into male fertility preservation for patients with completely immotile spermatozoa

    Sperm cryopreservation is the most effective method to preserve male fertility but this is normally used for motile spermatozoa. Thus, only motile spermatozoa are used for cryopreservation in most reproductive...

    Huanhua Chen, Guixue Feng, Bo Zhang, Hong Zhou, Caizhu Wang, Jinhui Shu, Xianyou Gan, Ruoyun Lin, Dongmei Huang and Yingqin Huang

    Reproductive Biology and Endocrinology 2017 15:74

    Published on: 18 September 2017

  14. Research

    Expression of factors involved in apoptosis and cell survival is correlated with enzymes synthesizing lysophosphatidic acid and its receptors in granulosa cells originating from different types of bovine ovarian follicles

    Lysophosphatidic acid (LPA) regulates reproductive processes in the cow. Ovarian granulosa cells play a pivotal role in follicle growth and development. Nevertheless, the role of LPA in the local regulation of...

    Emilia Sinderewicz, Katarzyna Grycmacher, Dorota Boruszewska, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz, Tomasz Ślężak and Izabela Woclawek-Potocka

    Reproductive Biology and Endocrinology 2017 15:72

    Published on: 6 September 2017

    The Correction to this article has been published in Reproductive Biology and Endocrinology 2017 15:82

  15. Research

    Controlled ovulation of the dominant follicle using progestin in minimal stimulation in poor responders

    The use of progestin (P) during ovarian stimulation is effective in blocking the luteinizing hormone (LH) surge in women with normal ovarian reserve, however, its effects have not been determined in poor respo...

    Qiuju Chen, Yun Wang, Lihua Sun, Shaozhen Zhang, Weiran Chai, Qingqing Hong, Hui Long, Li Wang, Qifeng Lyu and Yanping Kuang

    Reproductive Biology and Endocrinology 2017 15:71

    Published on: 5 September 2017

  16. Research

    Does daily co-administration of letrozole and gonadotropins during ovarian stimulation improve IVF outcome?

    For the last year we have been treating normal responders with gonadotropins and letrozole during the whole stimulation in order to improve response to FSH by increasing the intrafollicular androgen concentrat...

    Jigal Haas, Rawad Bassil, Jim Meriano, Nivin Samara, Eran Barzilay, Noa Gonen and Robert F. Casper

    Reproductive Biology and Endocrinology 2017 15:70

    Published on: 30 August 2017

  17. Research

    Plk1 is essential for proper chromosome segregation during meiosis I/meiosis II transition in pig oocytes

    Polo-like kinase 1 (Plk1), as a characteristic regulator in meiosis, organizes multiple biological events of cell division. Although Plk1 has been implicated in various functions in somatic cell mitotic proces...

    Zixiao Zhang, Changchao Chen, Liying Ma, Qiuchen Yu, Shuai Li, Benazir Abbasi, Jiayi Yang, Rong Rui and Shiqiang Ju

    Reproductive Biology and Endocrinology 2017 15:69

    Published on: 29 August 2017

  18. Research

    The decreased expression of TIPE2 protein in the decidua of patients with missed abortion and possible significance

    Missed abortion is a common occurrence for otherwise healthy women. Immunological factor is one of the most important reasons. Tumor necrosis factor-α-induced protein-8 like-2 (TIPE2) is a novel negative immun...

    Yingshuo Sun, Xiaoyan Wang, Yue Li, Han Sun, Lu Wan, Xishuang Wang, Lining Zhang, Zhenghui Fang and Zengtao Wei

    Reproductive Biology and Endocrinology 2017 15:68

    Published on: 29 August 2017

  19. Research

    Determining optimal gestational weight gain in the Korean population: a retrospective cohort study

    The World Health Organization (WHO) international body mass index (BMI) cut-off points defining pre-pregnancy BMI categories in the Institute of Medicine (IOM) guidelines are not directly applicable to Asians....

    Sae Kyung Choi, Guisera Lee, Yeon Hee Kim, In Yang Park, Hyun Sun Ko and Jong Chul Shin

    Reproductive Biology and Endocrinology 2017 15:67

    Published on: 22 August 2017

  20. Research

    NLRP7 contributes to in vitro decidualization of endometrial stromal cells

    Nucleotide-binding oligomerization domain (NACHT), leucine rich repeat (LRR) and pyrin domain (PYD) 7 containing protein, NLRP7, is a member of the NLR family which serves as innate immune sensors. Mutations a...

    Jyun-Yuan Huang, Pei-Hsiu Yu, Yueh-Chun Li and Pao-Lin Kuo

    Reproductive Biology and Endocrinology 2017 15:66

    Published on: 15 August 2017

  21. Review

    The Catsper channel and its roles in male fertility: a systematic review

    The Catsper channel is a sperm-specific, Ca2+-permeable, pH-dependent, and low voltage-dependent channel that is essential for the hyperactivity of sperm flagellum, chemotaxis towards the egg, capacitation and ac...

    Xiang-hong Sun, Ying-ying Zhu, Lin Wang, Hong-ling Liu, Yong Ling, Zong-li Li and Li-bo Sun

    Reproductive Biology and Endocrinology 2017 15:65

    Published on: 15 August 2017

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