Articles

Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol

Estrogens play an important role in the regulation of placental function, and 17-beta-estradiol (E2) production rises eighty fold during human pregnancy. Although term placenta has been found to specifically b...

Authors: Antonin Bukovsky, Maria Cekanova, Michael R Caudle, Jay Wimalasena, James S Foster, Donald C Henley and Robert F Elder

The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle

In the mammalian ovary, great interest in the expression and function of the bone morphogenetic protein (BMP) family has been recently generated from evidence of their critical role in determining folliculogen...

Authors: Gregory F Erickson and Shunichi Shimasaki

Effect of long-term treatment with steroid hormones or tamoxifen on the progesterone receptor and androgen receptor in the endometrium of ovariectomized cynomolgus macaques

The progesterone receptor (PR) and androgen receptor (AR) belong to the nuclear receptor superfamily. Two isoforms of PR (A and B) have been identified with different functions. The expression of AR, each isof...

Authors: Hong Wang, Erika Isaksson, Bo von Schoultz, J Mark Cline and Lena Sahlin

Rat testicular germ cells and sertoli cells release different types of bioactive transforming growth factor beta in vitro

Several in vivo studies have reported the presence of immunoreactive transforming growth factor-β's (TGF-β's) in testicular cells at defined stages of their differentiation. The most pronounced changes in TGF-β₁ ...

Authors: Bart L Haagmans, Jos W Hoogerbrugge, Axel PN Themmen and Katja J Teerds

Apamin inhibits NO-induced relaxation of the spontaneous contractile activity of the myometrium from non-pregnant women

There is now considerable evidence for the involvement of K⁺ channels in nitric oxide (NO) induced relaxation of smooth muscles including the myometrium. In order to assess whether apamin-sensitive K⁺ channels pl...

Authors: Beata Modzelewska, Anna Kostrzewska, Marek Sipowicz, Tomasz Kleszczewski and Satish Batra

Ovarian responses to undernutrition in pregnant ewes, USA

In most mammals oogonia proliferate by mitosis and begin meiotic development during fetal life. Previous studies indicated that there is a delay in the progression to the first stage of meiotic arrest in germ ...

Authors: William J Murdoch, Edward A Van Kirk, Kimberly A Vonnahme and Stephen P Ford

Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice

During mammalian testis development distinct generations of fetal and adult Leydig cells arise. Luteinising hormone (LH) is required for normal adult Leydig cell function and for the establishment of normal ad...

Authors: PJ Baker, H Johnston, M Abel, HM Charlton and PJ O'Shaughnessy

Relaxin receptors and nitric oxide synthases: search for the missing link

Authors: Silvia Nistri and Daniele Bani

Transmembrane and truncated (SEC) isoforms of MUC1 in the human endometrium and Fallopian tube

The cell surface mucin MUC1 is expressed by endometrial epithelial cells with increased abundance in the secretory phase of the menstrual cycle, when it is found both at the apical cell surface and in secretio...

Authors: Neil A Hey, Marcos Meseguer, Carlos Simón, Nechama I Smorodinsky, Daniel H Wreschner, María Elena Ortíz and John D Aplin

Reproductive Biology and Endocrinology – Choose an exciting venture for the scientific future

Authors: Antonin Bukovsky