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  1. Hyperandrogenic conditions have been associated with a high prevalence of endometrial pathologies related to cell survival. However, the action of androgens on proliferation and apoptosis in endometrial cells ...

    Authors: Manuel A Maliqueo, Susana Quezada, Marisa Clementi, Ketty Bacallao, Mabel Anido, Cecilia Johnson and Margarita Vega

    Citation: Reproductive Biology and Endocrinology 2004 2:81

    Content type: Research

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  2. 17alpha-hydroxyprogesterone caproate (17P) administration reportedly improves outcome for women with a previous spontaneous preterm delivery. This study, using in vitro strips of human uterine smooth muscle, a...

    Authors: Donal J Sexton, Michael W O'Reilly, Anne M Friel and John J Morrison

    Citation: Reproductive Biology and Endocrinology 2004 2:80

    Content type: Research

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  3. Little is known about how hormones interact in the photoperiodic induction of seasonal responses in birds. In this study, two experiments determined if the treatment with melatonin altered inhibitory effects o...

    Authors: Amit K Trivedi, Sangeeta Rani and Vinod Kumar

    Citation: Reproductive Biology and Endocrinology 2004 2:79

    Content type: Research

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  4. Recently, several members of the transforming growth factor-beta (TGF-beta) superfamily have been shown to be essential for regulating the growth and differentiation of ovarian follicles and thus fertility.

    Authors: Jennifer L Juengel, Adrian H Bibby, Karen L Reader, Stan Lun, Laurel D Quirke, Lisa J Haydon and Kenneth P McNatty

    Citation: Reproductive Biology and Endocrinology 2004 2:78

    Content type: Research

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  5. After fertilization, embryo development involves differentiation, as well as development of the fetal body and extra-embryonic tissues until the moment of implantation. During this period various cellular and ...

    Authors: Koichi Ushizawa, Chandana B Herath, Kanako Kaneyama, Satoshi Shiojima, Akira Hirasawa, Toru Takahashi, Kei Imai, Kazuhiko Ochiai, Tomoyuki Tokunaga, Yukio Tsunoda, Gozoh Tsujimoto and Kazuyoshi Hashizume

    Citation: Reproductive Biology and Endocrinology 2004 2:77

    Content type: Research

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  6. Implantation of the embryo and successful pregnancy are dependent on the differentiation of endometrial stromal cells into decidual cells. Female interleukin-11 receptor α (IL-11Rα) deficient mice are infertil...

    Authors: Christine A White, Lorraine Robb and Lois A Salamonsen

    Citation: Reproductive Biology and Endocrinology 2004 2:76

    Content type: Research

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  7. Cervical ripening is an inflammatory reaction. The glucocorticoid receptor (GR) mediates glucocorticoid anti-inflammatory reactions, whereas nuclear factor (NF)kappaB is a key pro-inflammatory transcription fa...

    Authors: Ylva Stjernholm-Vladic, Denis Stygar, Christopher Mansson, Britt Masironi, Sonja Akerberg, Hong Wang, Gunvor Ekman-Ordeberg and Lena Sahlin

    Citation: Reproductive Biology and Endocrinology 2004 2:74

    Content type: Research

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  8. Carbonic anhydrase (CA) classically catalyses the reversible hydration of dissolved CO2 to form bicarbonate ions and protons. The twelve active CA isozymes are thought to regulate a variety of cellular functions ...

    Authors: Piritta Hynninen, Jonna M Hämäläinen, Silvia Pastorekova, Jaromir Pastorek, Abdul Waheed, William S Sly, Eija Tomas, Pertti Kirkinen and Seppo Parkkila

    Citation: Reproductive Biology and Endocrinology 2004 2:73

    Content type: Research

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  9. In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is c...

    Authors: Sandrine Cassy, Sonia Metayer, Sabine Crochet, Nicole Rideau, Anne Collin and Sophie Tesseraud

    Citation: Reproductive Biology and Endocrinology 2004 2:72

    Content type: Research

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  10. Inhibins are dimeric gonadal protein hormones that negatively regulate pituitary FSH synthesis and secretion. Inhibin B is produced by testicular Sertoli cells and is the primary circulating form of inhibin in...

    Authors: Daniel J Bernard, Teresa K Woodruff and Tony M Plant

    Citation: Reproductive Biology and Endocrinology 2004 2:71

    Content type: Research

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  11. The objective of this randomized prospective study was to compare the efficacy of 50 mcg vaginal misoprostol and 3 mg dinoprostone, administered every nine hours for a maximum of three doses, for elective indu...

    Authors: Evangelos G Papanikolaou, Nikos Plachouras, Aikaterini Drougia, Styliani Andronikou, Christina Vlachou, Theodoros Stefos, Evangelos Paraskevaidis and Konstantinos Zikopoulos

    Citation: Reproductive Biology and Endocrinology 2004 2:70

    Content type: Research

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  12. Endometriosis is a condition that affects women of reproductive age, where the glandular and/or stromal tissues from the eutopic endometrium implant in ectopic locations. It is well established that the surviv...

    Authors: Romina S Ilad, Steven D Fleming, Catherine R Bebington and Christopher R Murphy

    Citation: Reproductive Biology and Endocrinology 2004 2:69

    Content type: Research

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  13. This review deals with the methods of identifying genes that have been activated by inner or outer impulses. The activation and subsequent expression of a gene can be detected by its transcription into a corre...

    Authors: Sten Z Cekan

    Citation: Reproductive Biology and Endocrinology 2004 2:68

    Content type: Review

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  14. Large-conductance, calcium-activated potassium (Maxi-K) channels are implicated in the modulation of human uterine contractions and myometrial Ca2+ homeostasis. However, the regulatory mechanism(s) governing the ...

    Authors: Michael Curley, John J Morrison and Terry J Smith

    Citation: Reproductive Biology and Endocrinology 2004 2:67

    Content type: Research

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  15. The endometrium prepares for implantation under the control of steroid hormones. It has been suggested that there are complicated interactions between the epithelium and stroma in the endometrium during menstr...

    Authors: Atsushi Yanaihara, Yukiko Otsuka, Shinji Iwasaki, Keiko Koide, Tadateru Aida and Takashi Okai

    Citation: Reproductive Biology and Endocrinology 2004 2:66

    Content type: Research

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  16. The C677T MTHFR variant has been associated with the same third trimester pregnancy complications as seen in women who have elevations of maternal serum α-fetoprotein (MSAFP). We hypothesized that these women ...

    Authors: Natalie K Björklund, Jane A Evans, Cheryl R Greenberg, Lorne E Seargeant, Carol E Schneider and Bernard N Chodirker

    Citation: Reproductive Biology and Endocrinology 2004 2:65

    Content type: Research

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  17. Elevated non-esterified fatty acids (NEFA) concentrations in non-pregnant animals have been reported to decrease pancreatic responsiveness. As ovine gestation advances, maternal insulin concentrations fall and...

    Authors: Timothy RH Regnault, Hutton V Oddy, Colin Nancarrow, Nadarajah Sriskandarajah and Rex J Scaramuzzi

    Citation: Reproductive Biology and Endocrinology 2004 2:64

    Content type: Research

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  18. Gonadotropin-primed immature rats (GPIR) constitute a widely used model for the study of ovulation. Although the equivalence between the ovulatory process in immature and adult rats is generally assumed, the m...

    Authors: María Gaytan, Carmen Bellido, Concepcion Morales, Marcelino Gonzalez-Padilla, Jose E Sanchez-Criado and Francisco Gaytan

    Citation: Reproductive Biology and Endocrinology 2004 2:63

    Content type: Research

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  19. This study was performed to investigate stress effects on the synthesis of egg yolk precursor, vitellogenin (Vtg) in Arctic char (Salvelinus alpinus). In particular the effect of cortisol (F) was determined since...

    Authors: Hakan Berg, Carina Modig and Per-Erik Olsson

    Citation: Reproductive Biology and Endocrinology 2004 2:62

    Content type: Research

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  20. The HE2 gene encodes a group of isoforms with similarities to the antimicrobial beta-defensins. We demonstrated earlier that the antimicrobial activity of HE2 proteins and peptides is salt resistant and struct...

    Authors: Suresh Yenugu, Katherine G Hamil, Frank S French and Susan H Hall

    Citation: Reproductive Biology and Endocrinology 2004 2:61

    Content type: Research

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  21. Although much is known about the reproductive biology of pond-breeding frogs, there is comparatively little information about terrestrial-breeding anurans, a highly successful and diverse group. This study inv...

    Authors: Esteban Toro and Scott F Michael

    Citation: Reproductive Biology and Endocrinology 2004 2:60

    Content type: Research

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  22. The aim of this study was to examine the invasiveness of first trimester trophoblasts according to the secretion profile of MMP-2 and -9 at different gestational stages, and to test the similarity between prim...

    Authors: Elsebeth Staun-Ram, Shlomit Goldman, Diana Gabarin and Eliezer Shalev

    Citation: Reproductive Biology and Endocrinology 2004 2:59

    Content type: Research

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  23. The maternal circulation to the human placenta is not fully established until 10–12 weeks of pregnancy. During the first trimester the intervillous space is filled by a clear fluid, in part derived from secret...

    Authors: Joanne Hempstock, Tereza Cindrova-Davies, Eric Jauniaux and Graham J Burton

    Citation: Reproductive Biology and Endocrinology 2004 2:58

    Content type: Research

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  24. There are different factors that influence treatment outcome after ovarian stimulation and timed-intercourse or intrauterine insemination (IUI). After patient age, it has been suggested that timing of insemina...

    Authors: Mohamed F Mitwally, Sonya Abdel-Razeq and Robert F Casper

    Citation: Reproductive Biology and Endocrinology 2004 2:55

    Content type: Research

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  25. In the endometrium the steroid hormone progesterone (P), acting through its nuclear receptors, regulates the expression of specific target genes and gene networks required for endometrial maturation. Proper en...

    Authors: Christopher I Ace and William C Okulicz

    Citation: Reproductive Biology and Endocrinology 2004 2:54

    Content type: Research

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  26. Implantation is a complex spatio-temporal interaction between the growing embryo and the mother, where both players need to be highly synchronized to be able to establish an effective communication to ensure a...

    Authors: Paula Cameo, Santha Srisuparp, Zuzana Strakova and Asgerally T Fazleabas

    Citation: Reproductive Biology and Endocrinology 2004 2:50

    Content type: Review

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  27. Establishment and maintenance of pregnancy results from signaling by the conceptus (embryo/fetus and associated extraembryonic membranes) and requires progesterone produced by the corpus luteum (CL). In most m...

    Authors: Thomas E Spencer and Fuller W Bazer

    Citation: Reproductive Biology and Endocrinology 2004 2:49

    Content type: Review

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  28. Implantation of the embryo in the uterus is a critical and complex event and its failure is widely considered an impediment to improved success in assisted reproduction. Depending on whether placentation is in...

    Authors: John D Aplin and Susan J Kimber

    Citation: Reproductive Biology and Endocrinology 2004 2:48

    Content type: Review

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  29. Based on the number of tissues separating maternal from fetal blood, placentas are classified as epitheliochorial, endotheliochorial or hemochorial. We review the occurrence of these placental types in the var...

    Authors: Anthony M Carter and Allen C Enders

    Citation: Reproductive Biology and Endocrinology 2004 2:46

    Content type: Review

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  30. In mammals, a carefully orchestrated dialogue between the mother and conceptus (embryo/fetus and associate extraembryonic membranes) is initiated during the peri-implantation period of pregnancy as the trophob...

    Authors: Thomas E Spencer and Fuller W Bazer

    Citation: Reproductive Biology and Endocrinology 2004 2:45

    Content type: Debate

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  31. The aim of this study was to investigate cumulus expansion, nuclear maturation and expression of connexin 43, cyclooxygenase-2 and FSH receptor transcripts in equine cumuli oophori during in vivo and in vitro ...

    Authors: Maria Elena Dell'Aquila, Maud Caillaud, Filippo Maritato, Alain Martoriati, Nadine Gérard, Giulio Aiudi, Paolo Minoia and Ghylène Goudet

    Citation: Reproductive Biology and Endocrinology 2004 2:44

    Content type: Research

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  32. Embryonic stem cells (ES) can self-replicate and differentiate into all cell types including insulin-producing, beta-like cells and could, therefore, be used to treat diabetes mellitus. To date, results of ste...

    Authors: Linda B Lester, Hung-Chih Kuo, Laura Andrews, Brian Nauert and Don P Wolf

    Citation: Reproductive Biology and Endocrinology 2004 2:42

    Content type: Review

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  33. Embryonic stem (ES) cell based therapy carries great potential in the treatment of neurodegenerative diseases. However, before clinical application is realized, the safety, efficacy and feasibility of this the...

    Authors: K-Y Francis Pau and Don P Wolf

    Citation: Reproductive Biology and Endocrinology 2004 2:41

    Content type: Review

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  34. Animal models that represent human diseases constitute an important tool in understanding the pathogenesis of the diseases, and in developing effective therapies. Neurodegenerative diseases are complex disorde...

    Authors: Anthony WS Chan

    Citation: Reproductive Biology and Endocrinology 2004 2:39

    Content type: Review

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  35. The assisted reproductive technologies (ARTs) have been used in the production of rhesus monkey offspring at the Oregon National Primate Research Center (ONPRC) and that experience is summarized here. Addition...

    Authors: Don P Wolf

    Citation: Reproductive Biology and Endocrinology 2004 2:37

    Content type: Review

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  36. In primates, the phase of the menstrual cycle when the uterus becomes receptive is initially dependent on estrogen and progesterone. Further morphological and biochemical changes are induced as a result of bio...

    Authors: J J Kim and Asgerally T Fazleabas

    Citation: Reproductive Biology and Endocrinology 2004 2:34

    Content type: Review

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  37. During the follicular phase of the primate menstrual cycle, a single follicle usually matures to the preovulatory stage and releases its oocyte for fertilization and the potential establishment of pregnancy. I...

    Authors: Anthony J Zeleznik

    Citation: Reproductive Biology and Endocrinology 2004 2:31

    Content type: Review

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