Haslam DW, James WP: Obesity. Lancet. 2005, 366: 1197-1209. 10.1016/S0140-6736(05)67483-1.
Article
PubMed
Google Scholar
World Health Organisation: Obesity: preventing and managing the global epidemic. 2000, Geneva: WHO Technical Report Series number 894
Google Scholar
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC: Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009, 120: 1640-1645. 10.1161/CIRCULATIONAHA.109.192644.
Article
CAS
PubMed
Google Scholar
Zeyda M, Stulnig TM: Obesity, inflammation, and insulin resistance - a mini-review. Gerontology. 2009, 55: 379-386. 10.1159/000212758.
Article
CAS
PubMed
Google Scholar
du Plessis SS, Cabler S, McAlister DA, Sabanegh E, Agarwal A: The effect of obesity on sperm disorders and male infertility. Nat Rev Urol. 2010, 7: 153-161. 10.1038/nrurol.2010.6.
Article
PubMed
Google Scholar
World Health Organisation: 2010, WHO Laboratory Manual for the Examination and Processing of Human Semen., 5, Department of Reproductive Health and Research
Kefer JC, Agarwal A, Sabanegh E: Role of antioxidants in the treatment of male infertility. Int J Urol. 2009, 16: 449-457. 10.1111/j.1442-2042.2009.02280.x.
Article
CAS
PubMed
Google Scholar
Aitken RJ: Sperm function tests and fertility. Int J Androl. 2006, 29: 69-75. 10.1111/j.1365-2605.2005.00630.x.
Article
CAS
PubMed
Google Scholar
Marchetti P, Ballot C, Jouy N, Thomas P, Marchetti C: Influence of mitochondrial membrane potential of spermatozoa on in vitro fertilisation outcome. Andrologia. 2012, 44: 136-141. 10.1111/j.1439-0272.2010.01117.x.
Article
CAS
PubMed
Google Scholar
Henkel R, Hoogendijk CF, Bouic PJ, Kruger TF: TUNEL assay and SCSA determine different aspects of sperm DNA damage. Andrologia. 2010, 42: 305-313. 10.1111/j.1439-0272.2009.01002.x.
Article
PubMed
Google Scholar
Hamada A, Esteves SC, Nizza M, Agarwal A: Unexplained male infertility: diagnosis and management. Int Braz J Urol. 2012, 38: 576-594. 10.1590/S1677-55382012000500002.
Article
PubMed
Google Scholar
Sermondade N, Faure C, Fezeu L, Shayeb AG, Bonde JP, Jensen TK, Van Wely M, Cao J, Martini AC, Eskandar M, Chavarro JE, Koloszar S, Twigt JM, Ramlau-Hansen CH, Borges E, Lotti F, Steegers-Theunissen RP, Zorn B, Polotsky AJ, La Vignera S, Eskenazi B, Tremellen K, Magnusdottir EV, Fejes I, Hercberg S, Lévy R, Czernichow S: BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis. Hum Reprod Update. 2013, 19: 221-231. 10.1093/humupd/dms050.
Article
PubMed Central
CAS
PubMed
Google Scholar
Palmer NO, Bakos HW, Fullston T, Lane M: Impact of obesity on male fertility, sperm function and molecular composition. Spermatogenesis. 2012, 1: 253-263.
Article
Google Scholar
Hammoud AO, Gibson M, Peterson CM, Meikle W, Carrell DT: Impact of male obesity on infertility: a critical review of the current literature. Fert Steril. 2008, 90: 897-904. 10.1016/j.fertnstert.2008.08.026.
Article
Google Scholar
MacDonald AA, Herbison GP, Showell M, Farquhar CM: The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis. Hum Reprod Update. 2010, 16: 293-311. 10.1093/humupd/dmp047.
Article
CAS
PubMed
Google Scholar
Bakos HW, Henshaw RC, Mitchell M, Lane M: Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology. Fertil Steril. 2011, 95: 1700-1704. 10.1016/j.fertnstert.2010.11.044.
Article
PubMed
Google Scholar
Lampiao F, Agarwal A, du Plessis SS: The role of insulin and leptin in male reproduction. Arch Med Sci. 2009, 5: S48-S54.
CAS
Google Scholar
Aquila S, Gentile M, Middea E, Catalano S, Andò S: Autocrine regulation of insulin secretion in human ejaculated spermatozoa. Endocrinology. 2005, 146: 552-557. 10.1210/en.2004-1252.
Article
CAS
PubMed
Google Scholar
Aquila S, Gentile M, Middea E, Catalano S, Morelli C, Pezzi V, Andò S: Leptin secretion by human ejaculated spermatozoa. J Clin Endocrinol Metab. 2005, 90: 4753-4761. 10.1210/jc.2004-2233.
Article
CAS
PubMed
Google Scholar
Andò S, Aquila S: Arguments raised by the recent discovery that insulin and leptin are expressed in and secreted by human ejaculated spermatozoa. Mol Cell Endocrinol. 2005, 245: 1-6. 10.1016/j.mce.2005.09.011.
Article
PubMed
Google Scholar
Lampiao F, du Plessis SS: Insulin and leptin enhance human sperm motility, acrosome reaction and nitric oxide production. Asian J Androl. 2008, 10: 799-807. 10.1111/j.1745-7262.2008.00421.x.
Article
CAS
PubMed
Google Scholar
Yokoyama H, Emoto M, Fujiwara S, Motoyama K, Morioka T, Komatsu M, Tahara H, Koyama H, Shoji T, Inaba M, Nishizawa Y: Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment are useful indexes of insulin resistance in type 2 diabetic patients with wide range of fasting plasma glucose. J Clin Endocrinol Metab. 2004, 89: 1481-1484. 10.1210/jc.2003-031374.
Article
CAS
PubMed
Google Scholar
Menkveld R, Stander FS, Kotze TJ, Kruger TF, van Zyl JA: The evaluation of morphological characteristics of human spermatozoa according to stricter criteria. Hum Reprod. 1990, 5: 586-592.
CAS
PubMed
Google Scholar
Politch JA, Tucker L, Bowman FP, Anderson DJ: Concentrations and significance of cytokines and other immunologic factors in semen of healthy fertile men. Hum Reprod. 2007, 22: 2928-2935. 10.1093/humrep/dem281.
Article
CAS
PubMed
Google Scholar
Henkel R, Fransman WO, Hipler UC, Wiegand C, Schreiber G, Menkveld R, Weitz F, Fisher D: Typha capensis (Rohrb.) N.E.Br. (bulrush) extract scavenges free radicals, inhibits collagenase activity and affects human sperm motility and mitochondrial membrane potential in vitro – a pilot study. Andrologia. 2012, 44 (Suppl. 1): 287-294.
Article
PubMed
Google Scholar
Quinn P, Kerin JF, Warnes GM: Improved pregnancy rate in human in vitro fertilization with the use of a medium based on the composition of human tubal fluid. Fertil Steril. 1985, 44: 493-498.
CAS
PubMed
Google Scholar
Henkel R, Hajimohammad M, Stalf T, Hoogendijk C, Mehnert C, Menkveld R, Gips H, Schill W-B, Kruger TF: Influence of deoxyribonucleic acid damage on fertilization and pregnancy. Fertil Steril. 2004, 81: 965-972. 10.1016/j.fertnstert.2003.09.044.
Article
CAS
PubMed
Google Scholar
Simon L, Proutski I, Stevenson M, Jennings D, McManus J, Lutton D, Lewis SE: Sperm DNA damage has a negative association with live-birth rates after IVF. Reprod Biomed Online. 2013, 26: 68-78. 10.1016/j.rbmo.2012.09.019.
Article
CAS
PubMed
Google Scholar
Fariello RM, Pariz JR, Spaine DM, Cedenho AP, Bertolla RP, Fraietta R: Association between obesity and alteration of sperm DNA integrity and mitochondrial activity. BJU Int. 2012, 110: 863-867. 10.1111/j.1464-410X.2011.10813.x.
Article
CAS
PubMed
Google Scholar
Huang PL: A comprehensive definition for metabolic syndrome. DMM. 2009, 2: 231-237. 10.1242/dmm.001180.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gallagher EJ, Leroith D, Karnieli E: Insulin resistance in obesity as the underlying cause for the metabolic syndrome. Mt Sinai J Med. 2010, 77: 511-523. 10.1002/msj.20212.
Article
PubMed
Google Scholar
Kwon H, Pessin JE: Adipokines mediate inflammation and insulin resistance. Front Endocrinol (Lausanne). 2013, 12: 71-
Google Scholar
Casabiell X, Piñeiro V, Vega F, De La Cruz LF, Diéguez C, Casanueva FF: Leptin, reproduction and sex steroids. Pituitary. 2001, 4: 93-99. 10.1023/A:1012999130035.
Article
CAS
PubMed
Google Scholar
Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B: Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006, 17: 4-12.
CAS
PubMed
Google Scholar
Hanafy S, Halawa FA, Mostafa T, Mikhael NW, Khalil KT: Serum leptin correlates in infertile oligozoospermic males. Andrologia. 2007, 39: 177-180. 10.1111/j.1439-0272.2007.00779.x.
Article
CAS
PubMed
Google Scholar
Zorn B, Osredkar J, Meden-Vrtovec H, Majdic G: Leptin levels in infertile male patients are correlated with inhibin B, testosterone and SHBG but not with sperm characteristics. Int J Androl. 2007, 30: 439-444. 10.1111/j.1365-2605.2006.00728.x.
Article
CAS
PubMed
Google Scholar
Niskanen L, Laaksonen DE, Punnonen K, Mustajoki P, Kaukua J, Rissanen A: Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome. Diabetes Obes Metab. 2004, 6: 208-215. 10.1111/j.1462-8902.2004.00335.x.
Article
CAS
PubMed
Google Scholar
Zitzmann M, Erren M, Kamischke A, Simoni M, Nieschlag E: Endogenous progesterone and the exogenous progestin norethisterone enanthate are associated with a proinflammatory profile in healthy men. J Clin Endocrinol Metab. 2005, 90: 6603-6608. 10.1210/jc.2005-0847.
Article
CAS
PubMed
Google Scholar
Schoeller EL, Albanna G, Frolova AI, Moley KH: Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in Akita diabetic mice and restores male fertility. Diabetes. 2012, 61: 1869-1878. 10.2337/db11-1527.
Article
PubMed Central
CAS
PubMed
Google Scholar
Paz G, Homonnai ZT, Ayalon D, Cordova T, Kraicer PF: Immunoreactive insulin in serum and seminal plasma of diabetic and nondiabetic men and its role in the regulation of spermatozoal activity. Fertil Steril. 1977, 28: 836-840.
CAS
PubMed
Google Scholar
Stahler MS, Budd GC, Pansky B: Evidence for insulin synthesis in normal mouse seminal vesicle based on in situ RNA-DNA hybridization. Biol Reprod. 1987, 36: 999-1006. 10.1095/biolreprod36.4.999.
Article
CAS
PubMed
Google Scholar
García-Díez LC, Corrales Hernandez JJ, Hernandez-Diaz J, Pedraz MJ, Miralles JM: Semen characteristics and diabetes mellitus: significance of insulin in male infertility. Arch Androl. 1991, 26: 119-128. 10.3109/01485019108987634.
Article
PubMed
Google Scholar
La Vignera S, Condorelli R, Vicari E, D'Agata R, Calogero AE: Diabetes mellitus and sperm parameters. J Androl. 2012, 33: 145-153. 10.2164/jandrol.111.013193.
Article
CAS
PubMed
Google Scholar
Li HW, Chiu PC, Cheung MP, Yeung WS, WS O: Effect of leptin on motility, capacitation and acrosome reaction of human spermatozoa. Int J Androl. 2009, 32: 687-694. 10.1111/j.1365-2605.2008.00931.x.
Article
CAS
PubMed
Google Scholar
Hicks JJ, Rojas L, Rosado A: Insulin regulation of spermatozoa metabolism. Endocrinology. 1973, 92: 833-839. 10.1210/endo-92-3-833.
Article
CAS
PubMed
Google Scholar
Povoa Junior H, Rezende MTL, Souza AC: Insulina imunoreativa em líquidos biológicos. Mem Inst Oswaldo Cruz. 1973, 71: 425-438. 10.1590/S0074-02761973000300006.
Article
Google Scholar
Truta Z, Garlovanu M, Lerintiu S, Micu R: A new method for human semen glucose concentration evaluation. Rom Biotech Lett. 2010, 15: 5764-5772.
CAS
Google Scholar
Diamandis EP, Arnett WP, Foussias G, Pappas H, Ghandi S, Melegos DN, Mullen B, Yu H, Srigley J, Jarvi K: Seminal plasma biochemical markers and their association with semen analysis findings. Urology. 1999, 53: 596-603. 10.1016/S0090-4295(98)00550-0.
Article
CAS
PubMed
Google Scholar
Alves MG, Martins AD, Rato L, Moreira PI, Socorro S, Oliveira PF: Molecular mechanisms beyond glucose transport in diabetes-related male infertility. Biochim Biophys Acta. 1832, 2013: 626-635.
Google Scholar