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  1. Content type: Research

    Hypogonadotropic hypogonadism (HH) in men results in insufficient testicular function and deficiencies in testosterone and spermatogenesis. Combinations of human chorionic gonadotropin (hCG) and recombinant fo...

    Authors: Eberhard Nieschlag, Pierre-Marc G. Bouloux, Barbara J. Stegmann, R. Ravi Shankar, Yanfen Guan, Anjela Tzontcheva, Christine McCrary Sisk and Hermann M. Behre

    Citation: Reproductive Biology and Endocrinology 2017 15:17

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  2. Content type: Research

    Chronic endometritis (CE) is a continuous inflammation of uterine endometrium, and it is usually symptomless. As CE has been thought not to affect the reproductive status and general health of affected women, ...

    Authors: Di Wu, Fuminori Kimura, Luyi Zheng, Mitsuaki Ishida, Yoko Niwa, Kimiko Hirata, Akie Takebayashi, Akiko Takashima, Kentaro Takahashi, Ryoji Kushima, Guangmei Zhang and Takashi Murakami

    Citation: Reproductive Biology and Endocrinology 2017 15:16

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  3. Content type: Research

    Activation of inflammation-mediated endometrial injury is suggested to play a decisive role in pathogenesis of intrauterine adhesion (IUA). The stem cell theory of endometrial diseases has been given a hotspot...

    Authors: Li Xiao, Yong Song, Wei Huang, Shiyuan Yang, Jing Fu, Xue Feng and Min Zhou

    Citation: Reproductive Biology and Endocrinology 2017 15:14

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  4. Content type: Review

    Polycystic ovary syndrome (PCOS) is a common endocrine disorder, affecting 9–18% of women in reproductive age that causes hyperandrogenism and infertility due to dysfunctional follicular maturation and anovula...

    Authors: Larissa Paixão, Ramon B. Ramos, Anita Lavarda, Debora M. Morsh and Poli Mara Spritzer

    Citation: Reproductive Biology and Endocrinology 2017 15:12

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  5. Content type: Research

    The influence of estradiol (E2) on granulosa cell (GC) function has not been tested clinically in women with polycystic ovary syndrome (PCOS). The objective of this study is to determine if E2 influences GC respo...

    Authors: Michael V. Homer, Marcus A. Rosencrantz, Rana F. Shayya and R. Jeffrey Chang

    Citation: Reproductive Biology and Endocrinology 2017 15:13

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  6. Content type: Research

    REAC technology (acronym for Radio Electric Asymmetric Conveyor) is a technology platform for neuro and bio modulation. It has already proven to optimize the ions fluxes at the molecular level and the molecula...

    Authors: Fiammetta Berlinguer, Valeria Pasciu, Sara Succu, Ignazio Cossu, Sabrina Caggiu, Daniela Addis, Alessandro Castagna, Vania Fontani, Salvatore Rinaldi and Eraldo Sanna Passino

    Citation: Reproductive Biology and Endocrinology 2017 15:11

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  7. Content type: Research

    This prospective, Phase IV, multicenter, observational registry of assisted reproductive technology clinics in the USA studied outcomes of first cycles using thawed/warmed cryopreserved (by slow-freezing/vitri...

    Authors: Zsolt Peter Nagy, Robert E. Anderson, Eve C. Feinberg, Brooke Hayward and Mary C. Mahony

    Citation: Reproductive Biology and Endocrinology 2017 15:10

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  8. Content type: Research

    Studies found that AGE-RAGE system is closely related to insulin resistance and hyperandrogenemia, which are two core pathophysiological processes in polycystic ovary syndrome (PCOS). This study is to investig...

    Authors: Yu Liao, Rong Huang, Yun Sun, Jiang Yue, Jun Zheng, Lihua Wang, Tao Tao, Jing Ma, Shengxian Li and Wei Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:9

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  9. Content type: Research

    Endometriosis has been described to impair fertility through various mechanisms. However, studies evaluating the reproductive outcomes of women undergoing assisted reproductive technologies show controversial ...

    Authors: Mireia González-Comadran, Juan Enrique Schwarze, Fernando Zegers-Hochschild, Maria do Carmo B. Souza, Ramon Carreras and Miguel Ángel Checa

    Citation: Reproductive Biology and Endocrinology 2017 15:8

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  10. Content type: Research

    The lifesaving chemotherapy and radiation treatments that allow patients to survive cancer can also result in a lifetime of side-effects, including male infertility. Infertility in male cancer survivors is tho...

    Authors: Travis Kotzur, Roberto Benavides-Garcia, Jennifer Mecklenburg, Jamila R. Sanchez, Matthew Reilly and Brian P. Hermann

    Citation: Reproductive Biology and Endocrinology 2017 15:7

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  11. Content type: Review

    Assisted Reproductive Technology (ART) has undergone considerable changes over the last decade, with consequences on ART outcomes in different regions of the world being unknown.

    Authors: Vitaly A. Kushnir, David H. Barad, David F. Albertini, Sarah K. Darmon and Norbert Gleicher

    Citation: Reproductive Biology and Endocrinology 2017 15:6

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  12. Content type: Research

    Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) are glycoprotein hormones regulating development and reproductive functions by acting on the same receptor (LHCGR). We compared the LH and hCG ac...

    Authors: Laura Riccetti, Francesco De Pascali, Lisa Gilioli, Francesco Potì, Lavinia Beatrice Giva, Marco Marino, Simonetta Tagliavini, Tommaso Trenti, Flaminia Fanelli, Marco Mezzullo, Uberto Pagotto, Manuela Simoni and Livio Casarini

    Citation: Reproductive Biology and Endocrinology 2017 15:2

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  13. Content type: Research

    In previous studies it has been shown that bovine granulosa cells (GC) cultured at a high plating density dramatically change their physiological and molecular characteristics, thus resembling an early stage o...

    Authors: Anja Baufeld, Dirk Koczan and Jens Vanselow

    Citation: Reproductive Biology and Endocrinology 2017 15:3

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  14. Content type: Research

    Secretion of histotroph during the prolonged pre-implantation phase in mares is crucial to pregnancy maintenance, manifested as increased embryonic loss in mares with age-related endometrial degeneration. Glyc...

    Authors: Sarah A. Bramer, Alysson Macedo and Claudia Klein

    Citation: Reproductive Biology and Endocrinology 2017 15:4

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  15. Content type: Research

    The study was designed to investigate the roles of endometrial thickness (EMT) at the day of human chorionic gonadotropin (hCG) administration on pregnancy outcomes in a large patient population.

    Authors: Ning-Zhao Ma, Lei Chen, Wei Dai, Zhi-Qin Bu, Lin-Li Hu and Ying-Pu Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:5

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  16. Content type: Research

    The junctional zone (JZ), also called as the endometrial-myometrial junction, is related to peristaltic-like movements in the non-pregnant uterus. Hyperperistalsis and dysperistalsis of uterus constructions mi...

    Authors: Miaomaio Huang, Xuqing Li, Peipei Guo, Zhaojuan Yu, Yuting Xu and Zhaolian Wei

    Citation: Reproductive Biology and Endocrinology 2017 15:1

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  17. Content type: Research

    There are reports showing that l-carnitine alone or in combination with other micronutrients improve sperm parameters. However, comparative studies are still lacking. This study was carried out to compare the ...

    Authors: Markus Lipovac, Florian Bodner, Martin Imhof and Peter Chedraui

    Citation: Reproductive Biology and Endocrinology 2016 14:84

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  18. Content type: Research

    The non-lethal collection of sperm from live males is an important component for multiple captive-breeding techniques, including assisted reproductive technology (ART) protocols, sperm cryopreservation and in ...

    Authors: Leah E. Jacobs, Jeanne M. Robertson and Kristine Kaiser

    Citation: Reproductive Biology and Endocrinology 2016 14:83

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  19. Content type: Research

    In mammalian females, reproductive capacity is determined by the size of the primordial follicle pool. During embryogenesis, oogonia divide mitotically but cytokinesis is incomplete so oogonia remain connected...

    Authors: Sudipta Dutta, Deion M. Burks and Melissa E. Pepling

    Citation: Reproductive Biology and Endocrinology 2016 14:82

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  20. Content type: Research

    Current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the establishment of endometriotic lesions. The aim of this study...

    Authors: Katharina Proestling, Peter Birner, Sukirthini Balendran, Nadine Nirtl, Erika Marton, Gülen Yerlikaya, Lorenz Kuessel, Theresa Reischer, Rene Wenzl, Berthold Streubel and Heinrich Husslein

    Citation: Reproductive Biology and Endocrinology 2016 14:81

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  21. Content type: Research

    Stress has been proved to impair the porcine reproduction soundly. Endocrine disruption, which is closely related to the persistent follicles, is possibly one of the results of stress, although the mechanism i...

    Authors: H. S. Zhu, Z. Qian, H. L. Liu and E. D. Bao

    Citation: Reproductive Biology and Endocrinology 2016 14:80

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  22. Content type: Research

    Phosphatidylserine is the phospholipid component which plays a key role in cell cycle signaling, specifically in regards to necrosis and apoptosis. When a cell affected by some negative factors, phosphatidylse...

    Authors: Vladimir Isachenko, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Bettina Hanstein, Mahmoud Salama, Peter Mallmann, Andrey Tchorbanov, Paul Hardiman, Natalie Getreu and Markus Merzenich

    Citation: Reproductive Biology and Endocrinology 2016 14:79

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  23. Content type: Research

    Cell-to-cell communication between the blastocyst and endometrium is critical for implantation. In recent years, evidence has emerged from studies in humans and several other animal species that exosomes are s...

    Authors: Yong Qin Koh, Hassendrini N. Peiris, Kanchan Vaswani, Sarah Reed, Gregory E. Rice, Carlos Salomon and Murray D. Mitchell

    Citation: Reproductive Biology and Endocrinology 2016 14:78

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  24. Content type: Research

    α1,3-Galactosyltransferase (GGTA1) is essential for the biosynthesis of glycoproteins and therefore a simple and effective target for disrupting the expression of galactose α-1,3-galactose epitopes, which medi...

    Authors: Wenmin Cheng, Heng Zhao, Honghao Yu, Jige Xin, Jia Wang, Luyao Zeng, Zaimei Yuan, Yubo Qing, Honghui Li, Baoyu Jia, Cejun Yang, Youfeng Shen, Lu Zhao, Weirong Pan, Hong-Ye Zhao, Wei Wang…

    Citation: Reproductive Biology and Endocrinology 2016 14:77

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  25. Content type: Review

    In the literature, there is growing evidence that subfertile patients who conceived after infertility treatments have an increased risk of pregnancy and perinatal complications and this is particularly true fo...

    Authors: Stefano Palomba, Roy Homburg, Susanna Santagni, Giovanni Battista La Sala and Raoul Orvieto

    Citation: Reproductive Biology and Endocrinology 2016 14:76

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  26. Content type: Research

    Muscarinic receptors (mAChRs) of the preoptic and anterior hypothalamus areas (POA-AHA) regulate ovulation in an asymmetric manner during the estrous cycle. The aims of the present study were to analyze the ef...

    Authors: Adriana Espinosa-Valdez, Angélica Flores, Isabel Arrieta-Cruz, Mario Cárdenas, Roberto Chavira, Roberto Domínguez and María Esther Cruz

    Citation: Reproductive Biology and Endocrinology 2016 14:75

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  27. Content type: Research

    Pigs with SCID can be a useful model in regenerative medicine, xenotransplantation, and cancer cell transplantation studies. Utilizing genome editing technologies such as CRISPR/Cas9 system allows us to genera...

    Authors: Jung-Taek Kang, Bumrae Cho, Junghyun Ryu, Caitlin Ray, Eun-Jin Lee, Yun-Jin Yun, SunMi Ahn, JinSeok Lee, Dal-Young Ji, Nathaniel Jue, Sherrie Clark-Deener, Kiho Lee and Kwang-Wook Park

    Citation: Reproductive Biology and Endocrinology 2016 14:74

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  28. Content type: Research

    Endometriosis has been shown to be associated with second- to third-trimester pregnancy complications such as preterm birth and placenta previa, but the evidence is inconsistent. We hypothesized that endometri...

    Authors: Tatsuya Fujii, Osamu Wada-Hiraike, Takeshi Nagamatsu, Miyuki Harada, Tetsuya Hirata, Kaori Koga, Tomoyuki Fujii and Yutaka Osuga

    Citation: Reproductive Biology and Endocrinology 2016 14:73

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  29. Content type: Research

    Serum anti-Müllerian hormone (AMH) concentration has been used to assess ovarian reserve in patients with endometriosis, especially when endometrioma surgery is involved. Previously, we reported that decreased...

    Authors: Ai Saito, Akira Iwase, Tomoko Nakamura, Satoko Osuka, Bayasula, Tomohiko Murase, Nao Kato, Chiharu Ishida, Sachiko Takikawa, Maki Goto and Fumitaka Kikkawa

    Citation: Reproductive Biology and Endocrinology 2016 14:72

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  30. Content type: Research

    During labour, the cervix undergoes a series of changes to allow the passage of the fetoplacental unit. While this visible transformation is well-described, the underlying and causative microscopic changes, in...

    Authors: Brenda F. Narice, Nicola H. Green, Sheila MacNeil and Dilly Anumba

    Citation: Reproductive Biology and Endocrinology 2016 14:70

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  31. Content type: Review

    Ectopic pregnancy is the leading cause of maternal morbidity and mortality during the first trimester and the incidence increases dramatically with assisted-reproductive technology (ART), occurring in approxim...

    Authors: Nicole Yoder, Reshef Tal and J. Ryan Martin

    Citation: Reproductive Biology and Endocrinology 2016 14:69

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  32. Content type: Research

    Cyclooxygenase (COX)-derived prostanoids (PGE2, PGI2) are important contributors to the process of decidualization. Previous studies showed the presence of Ang-(1-7) in the primary and secondary decidualized zone...

    Authors: K. Bridget Brosnihan, Victor M. Pulgar, Manish S. Bharadwaj, Liomar A. A. Neves and Liliya M. Yamaleyeva

    Citation: Reproductive Biology and Endocrinology 2016 14:68

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    The Erratum to this article has been published in Reproductive Biology and Endocrinology 2017 15:22

  33. Content type: Research

    Recently emerging evidence indicates that endometriotic lesions are wounds undergoing repeated tissue injury and repair (ReTIAR), and platelets induce epithelial-mesenchymal transition (EMT), fibroblast-to-myo...

    Authors: Bo Zhu, Yumei Chen, Xiaolu Shen, Xishi Liu and Sun-Wei Guo

    Citation: Reproductive Biology and Endocrinology 2016 14:66

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  34. Content type: Research

    ATF6α, one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum, is located in the membrane of the endoplasmic reticulum. To date, the physiological function of ATF6α in the proc...

    Authors: Yongjie Xiong, Wenzhe Li, Pengfei Lin, Lei Wang, Nan Wang, Fenglei Chen, Xiao Li, Aihua Wang and Yaping Jin

    Citation: Reproductive Biology and Endocrinology 2016 14:65

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  35. Content type: Research

    Iatrogenic parasitic myomas (PMs), caused by intra-corporeal power morcellation during laparoscopy is gradually increasing. However, the pathogenesis and medical treatment of PMs remain largely unelucidated.

    Authors: Ben-Shian Huang, Muh-Hwa Yang, Peng-Hui Wang, Hsin-Yang Li, Teh-Ying Chou and Yi-Jen Chen

    Citation: Reproductive Biology and Endocrinology 2016 14:64

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  36. Content type: Research

    Previous studies have explored the effect of granulocyte colony stimulating factor (G-CSF) administration on the outcome of assisted reproductive technology (ART), and came into controversial conclusions. The ...

    Authors: J. Zhao, B. Xu, S. Xie, Q. Zhang and Y. P. Li

    Citation: Reproductive Biology and Endocrinology 2016 14:62

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  37. Content type: Research

    Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy, and has important health implications for mother and child. Changes in the fetoplacental vessels may predict th...

    Authors: Qian Meng, Li Shao, Xiucui Luo, Yingping Mu, Wen Xu, Li Gao, Haoqin Xu and Yugui Cui

    Citation: Reproductive Biology and Endocrinology 2016 14:61

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  38. Content type: Research

    Adenomyosis is linked to infertility, but the mechanisms behind this relationship are not clearly established. Similarly, the impact of adenomyosis on ART outcome is not fully understood. Our main objective wa...

    Authors: J. M. Puente, A. Fabris, J. Patel, A. Patel, M. Cerrillo, A. Requena and J. A. Garcia-Velasco

    Citation: Reproductive Biology and Endocrinology 2016 14:60

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  39. Content type: Research

    Endometritis reduces fertility and is responsible for major economic losses in beef and dairy industries. The aim of this study was to evaluate an alternative therapy using platelet-rich plasma (PRP). PRP was ...

    Authors: Maria Giovanna Marini, Claudia Perrini, Paola Esposti, Bruna Corradetti, Davide Bizzaro, Pietro Riccaboni, Eleonora Fantinato, Giuseppe Urbani, Giorgio Gelati, Fausto Cremonesi and Anna Lange-Consiglio

    Citation: Reproductive Biology and Endocrinology 2016 14:58

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  40. Content type: Research

    Angiogenesis is an essential process in endometriosis disease progression. Earlier, we demonstrated that anti-angiogenic peptide, ABT-898 prevents neoangiogenesis of human endometriotic lesions in a xenograft ...

    Authors: Andrew K. Edwards, Irina Olariu, Diane S. Nakamura, Soo Hyun Ahn and Chandrakant Tayade

    Citation: Reproductive Biology and Endocrinology 2016 14:56

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  41. Content type: Research

    The status characterized by the imbalance between pro-oxidants and antioxidants molecules, defined as oxidative stress, has been suggested to be involved in the pathogenesis of subfertility in females. This st...

    Authors: Alice Luddi, Angela Capaldo, Riccardo Focarelli, Martina Gori, Giuseppe Morgante, Paola Piomboni and Vincenzo De Leo

    Citation: Reproductive Biology and Endocrinology 2016 14:57

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  42. Content type: Short communication

    Preimplantation genetic screening (PGS) provides an opportunity to eliminate a potential implantation failure due to aneuploidy in infertile couples. Some studies clearly show that twins following single embry...

    Authors: Daniela Bettio, Antonio Capalbo, Elena Albani, Laura Rienzi, Valentina Achille, Anna Venci, Filippo Maria Ubaldi and Paolo Emanuele Levi Setti

    Citation: Reproductive Biology and Endocrinology 2016 14:55

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  43. Content type: Research

    To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such bi...

    Authors: Norbert Gleicher, Andrea Vidali, Jeffrey Braverman, Vitaly A. Kushnir, David H. Barad, Cynthia Hudson, Yang-Guan Wu, Qi Wang, Lin Zhang and David F. Albertini

    Citation: Reproductive Biology and Endocrinology 2016 14:54

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  44. Content type: Research

    In Spanish public hospital Reproduction Units it is very problematic to perform programmed intrauterine insemination (IUI) on weekends, if indicated. Small previous pilot studies suggest that using a GnRH anta...

    Authors: J. Gobernado, C. Alvarez-Colomo, L. Rodriguez-Tabernero, L. Barrero, J. M. F. Fernández-Gómez and J. Schneider

    Citation: Reproductive Biology and Endocrinology 2016 14:53

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  45. Content type: Research

    d-chiroinositol (DCI) is a inositolphosphoglycan (IPG) involved in several cellular functions that control the glucose metabolism. DCI functions as second messenger in the insulin signaling pathway and it is c...

    Authors: Sandro Sacchi, Federica Marinaro, Debora Tondelli, Jessica Lui, Susanna Xella, Tiziana Marsella, Daniela Tagliasacchi, Cindy Argento, Alessandra Tirelli, Simone Giulini and Antonio La Marca

    Citation: Reproductive Biology and Endocrinology 2016 14:52

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