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  1. This study was made to figure out, does low and high estradiol levels during in vitro fertilization (IVF) cycles have a different effect on carotid artery distensibility (Cdis), carotid artery diameter (Cdia),...

    Authors: Jonna Leppänen, Kaisa Randell, Ursula Schwab, Jussi Pihlajamäki, Leea Keski-Nisula, Tomi Laitinen and Seppo Heinonen

    Citation: Reproductive Biology and Endocrinology 2020 18:44

    Content type: Research

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  2. Follicular fluid is an important external environment for the growth and development of oocytes. A thorough identification of specific components in follicular fluid can better the existing understand of intra...

    Authors: Xingxing Zhang, Tianqi Wang, Jingyan Song, Jifeng Deng and Zhengao Sun

    Citation: Reproductive Biology and Endocrinology 2020 18:42

    Content type: Research

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  3. Patients with severe oligospermia and nonobstructive azoospermia have very limited numbers of viable sperm in their epididymal and testicular samples. Thus, cryopreservation of their sperm is performed to avoi...

    Authors: Shasha Liu and Fuping Li

    Citation: Reproductive Biology and Endocrinology 2020 18:41

    Content type: Review

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  4. The role of prostaglandin E2 (PGE2) in the successful resumption of oocyte meiosis and cumulus expansion has been well-documented. However, there remains very little information available on the influence of PGE2

    Authors: Dorota Boruszewska, Ilona Kowalczyk-Zieba, Katarzyna Suwik, Joanna Staszkiewicz-Chodor, Joanna Jaworska, Krzysztof Lukaszuk and Izabela Woclawek-Potocka

    Citation: Reproductive Biology and Endocrinology 2020 18:40

    Content type: Research

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  5. Germinal vesicle breakdown (GVBD) occurs during oocyte meiotic maturation, a period when transcriptional processes are virtually inactive. Thus, the maturing oocyte is reliant on processes such as post-transcr...

    Authors: Benjamin J. Hale, Yunsheng Li, Malavika K. Adur and Jason W. Ross

    Citation: Reproductive Biology and Endocrinology 2020 18:39

    Content type: Research

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  6. Human papillomavirus (HPV) has been considered as one of the most common sexually transmitted viruses that may be linked to unexplained infertility in men. The possible mechanisms underlying correlation betwee...

    Authors: Xiaodan Cao, Renxiong Wei, Xiaoxia Zhang, Jun Zhou, Jiangtao Lou and Yun Cui

    Citation: Reproductive Biology and Endocrinology 2020 18:38

    Content type: Review

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  7. We had previously demonstrated that vitrification reduces the levels of certain phospholipid classes, and that oocytes from aged mice show a similar lipidome alteration, even without vitrification. In the curr...

    Authors: Da-Eun Um, Hyejin Shin, Dayoung Park, Jeong Min Ahn, Jayeon Kim, Haengseok Song and Hyunjung Jade Lim

    Citation: Reproductive Biology and Endocrinology 2020 18:37

    Content type: Research

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  8. The endometrial preparation during frozen embryo transfer (FET) can be performed by natural cycle (NC), hormone replacement therapy (HRT) cycle and cycle with ovulation induction (OI). Whether different FET pr...

    Authors: Liping Zong, Peihao Liu, Liguang Zhou, Daimin Wei, Lingling Ding and Yingying Qin

    Citation: Reproductive Biology and Endocrinology 2020 18:36

    Content type: Research

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  9. The purpose of this study was to assess whether increased body mass index (BMI) negatively affects assisted reproductive technology (ART) outcomes among gestational carriers.

    Authors: Noga Fuchs Weizman, Miranda K. Defer, Janice Montbriand, Julia M. Pasquale, Adina Silver and Clifford L. Librach

    Citation: Reproductive Biology and Endocrinology 2020 18:35

    Content type: Research

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  10. Assisted reproductive technology (ART) insurance mandates resulted in improved access to infertility treatments like intracytoplasmic sperm injection (ICSI). Our objective was to examine whether ART insurance ...

    Authors: Pavel Zagadailov, David B. Seifer, He Shan, Shvetha M. Zarek and Albert L. Hsu

    Citation: Reproductive Biology and Endocrinology 2020 18:33

    Content type: Research

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  11. The interface between environmental risk factors and genetic factors could contribute to the pathogenesis of hyperandrogenism and insulin resistance in polycystic ovary syndrome (PCOS); however, the underlying...

    Authors: Junyu Zhai, Shang Li, Min Hu, Fangfang Di, Jiansheng Liu and Yanzhi Du

    Citation: Reproductive Biology and Endocrinology 2020 18:32

    Content type: Research

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  12. A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stro...

    Authors: Kanetoshi Takebayashi, Kaei Nasu, Mamiko Okamoto, Yoko Aoyagi, Tomoko Hirakawa and Hisashi Narahara

    Citation: Reproductive Biology and Endocrinology 2020 18:31

    Content type: Research

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  13. Onset of spermatogenesis at puberty is critically dependent on the activity of hypothalamic-pituitary-gonadal axis and testosterone production by Leydig cells. The aim of this study was to examine whether acti...

    Authors: Alicja Kamińska, Sylwia Marek, Laura Pardyak, Małgorzata Brzoskwinia, Piotr Pawlicki, Barbara Bilińska and Anna Hejmej

    Citation: Reproductive Biology and Endocrinology 2020 18:30

    Content type: Research

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  14. Cold, an environmental factor, induces many reproductive diseases. It is known that endothelin (ET) is a potent vasoconstrictor, and cold stress can increase the expression of ET and its receptors. The cold st...

    Authors: Di Wang, Xiumei Cheng, Huimin Fang, Yanqing Ren, Xinhua Li, Weiwei Ren, Bing Xue and Cairui Yang

    Citation: Reproductive Biology and Endocrinology 2020 18:29

    Content type: Research

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  15. Chronic cyclic pelvic pain (CCPP) affects women’s quality of life and pituitary downregulation is often used for symptomatic relief. However, prolonged suppression of ovarian function is associated with menopa...

    Authors: Sallwa M. Alshehre, Sheila Duffy, Georgina Jones, William L. Ledger and Mostafa Metwally

    Citation: Reproductive Biology and Endocrinology 2020 18:28

    Content type: Research

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  16. The study aimed to investigate whether and how general and partial time intervals between processes, from human chorionic gonadotrophin (HCG) trigger to intracytoplasmic sperm injection (ICSI), affected the la...

    Authors: Yini Zhang, Yongzhuang Ma, Zishui Fang, Shiqiao Hu, Zhou Li, Lixia Zhu and Lei Jin

    Citation: Reproductive Biology and Endocrinology 2020 18:27

    Content type: Research

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  17. We have previously shown that hsa-miR-423-5p expression in ovarian granulosa cells is decreased in high ovarian response populations. The objective of the present study was to find the target gene and mechanis...

    Authors: Shi Xie, Qiong Zhang, Jing Zhao, Jie Hao, Jing Fu and Yanping Li

    Citation: Reproductive Biology and Endocrinology 2020 18:26

    Content type: Research

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  18. Type 2 diabetes touches young subjects of reproductive age in epidemic proportion. This study assesses glucose, total InsulinT, Insulin2 and insulin receptor subunits α and β in testis during mouse development...

    Authors: R.-Marc Pelletier, Hamed Layeghkhavidaki and María L. Vitale

    Citation: Reproductive Biology and Endocrinology 2020 18:25

    Content type: Research

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  19. Molecular analyses of vitamin D in a typical cycling endometrium has received minimal research attention in the reproductive field. This study was designed to assess how expression of the endometrial vitamin D...

    Authors: Jing Guo, Shan Liu, Peng Wang, Haiying Ren and Yuan Li

    Citation: Reproductive Biology and Endocrinology 2020 18:24

    Content type: Research

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  20. A limited number of publications have assessed the prevalence of hypertension (HTN) in polycystic ovary syndrome (PCOS) patients with inconclusive results. Since in general populations the occurrence of hypert...

    Authors: Mina Amiri, Fahimeh Ramezani Tehrani, Samira Behboudi-Gandevani, Razieh Bidhendi-Yarandi and Enrico Carmina

    Citation: Reproductive Biology and Endocrinology 2020 18:23

    Content type: Review

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  21. Bisphenol-A (BPA) has been reported to be associated to female infertility. Indeed, BPA has been found to be more frequently detected in infertile women thus leading to hypothesize a possible effect of BPA on ...

    Authors: Claudia Pivonello, Giovanna Muscogiuri, Antonio Nardone, Francesco Garifalos, Donatella Paola Provvisiero, Nunzia Verde, Cristina de Angelis, Alessandro Conforti, Mariangela Piscopo, Renata Simona Auriemma, Annamaria Colao and Rosario Pivonello

    Citation: Reproductive Biology and Endocrinology 2020 18:22

    Content type: Review

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  22. Considerable interest has been gathered on the relevant impact of preventable factors, including incorrect lifestyle and unhealthy habits, on female fertility. Smoking, alcohol and addictive drugs consumption ...

    Authors: Cristina de Angelis, Antonio Nardone, Francesco Garifalos, Claudia Pivonello, Andrea Sansone, Alessandro Conforti, Carla Di Dato, Felice Sirico, Carlo Alviggi, Andrea Isidori, Annamaria Colao and Rosario Pivonello

    Citation: Reproductive Biology and Endocrinology 2020 18:21

    Content type: Review

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  23. Antimullerian hormone (AMH) strongly correlates with ovarian reserve and response to controlled ovarian stimulation. Emerging data suggests that serum AMH level may also predict ART outcomes. However, AMH is c...

    Authors: Reshef Tal, Charles M. Seifer, Moisey Khanimov, David B. Seifer and Oded Tal

    Citation: Reproductive Biology and Endocrinology 2020 18:20

    Content type: Research

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  24. Several studies from the US and Europe have shown a population-level decline in serum testosterone in men from 1970’s to early 2000’s. However, to the best of our knowledge, no study examining population-level...

    Authors: Gabriel Chodick, Shdema Epstein and Varda Shalev

    Citation: Reproductive Biology and Endocrinology 2020 18:19

    Content type: Short communication

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  25. Polycystic ovarian syndrome (PCOS) is a multi-gene hereditary disorder caused by the interaction of certain gene variation with environmental factors. Previous studies have shown that vascular endothelial grow...

    Authors: Jiahui Zhao, Da Li, Huaiyun Tang and Lisha Tang

    Citation: Reproductive Biology and Endocrinology 2020 18:18

    Content type: Review

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  26. Sperm cryopreservation has been widely used in assisted reproductive technology (ART) and has resulted in millions of live births. Two principal approaches have been adopted: conventional (slow) freezing and v...

    Authors: Yong Tao, Erika Sanger, Arpornrad Saewu and Marie-Claude Leveille

    Citation: Reproductive Biology and Endocrinology 2020 18:17

    Content type: Review

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  27. To investigate the effectiveness of the GnRH-a ultra-long protocol, GnRH-a long protocol, and GnRH-a short protocol used in in vitro fertilization-embryo transfer (IVF-ET) in infertile women with endometriosis.

    Authors: Xue Cao, Hong-yang Chang, Jun-yan Xu, Yi Zheng, Yun-gai Xiang, Bing Xiao, Xu-jing Geng, Li-li Ni, Xi-ying Chu, Shi-bo Tao, Yan He and Gen-hong Mao

    Citation: Reproductive Biology and Endocrinology 2020 18:16

    Content type: Research

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  28. The study is aimed to provide prediction for fertility risk in the setting of assisted reproduction for a woman with complex chromosomal rearrangements (CCRs).

    Authors: Jian Ou, Chuanchun Yang, Xiaoli Cui, Chuan Chen, Suyan Ye, Cai Zhang, Kai Wang, Jianguo Chen, Qin Zhang, Chunfeng Qian, Guangguang Fang and Wenyong Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:15

    Content type: Research

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  29. In recent years, some studies have shown that there is a positive association between the number of oocytes retrieved and the cumulative live birth rate (CLBR) after fresh and frozen cycles of one oocyte retri...

    Authors: Zhonghua Zhao, Hao Shi, Jing Li, Yile Zhang, Caihong Chen and Yihong Guo

    Citation: Reproductive Biology and Endocrinology 2020 18:14

    Content type: Research

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  30. Pregnant women have high serum concentrations of sex steroid hormones, which are major regulators of paracrine and autocrine responses for many maternal and placental functions. The main purpose of this study ...

    Authors: Kuo-Chung Lan, Yun-Ju Lai, Hsin-Hsin Cheng, Ni-Chin Tsai, Yu-Ting Su, Ching-Chang Tsai and Te-Yao Hsu

    Citation: Reproductive Biology and Endocrinology 2020 18:12

    Content type: Research

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  31. BRCA mutation carriers face various situations that influence their fertility potential. There is still a lack of guideline or expert consensus on Fertility Preservation (FP) in BRCA mutation carriers and the ...

    Authors: Xiaofu Zhang, Jingxin Niu, Tuanjie Che, Yibei Zhu, Hongtao Zhang and Jing Qu

    Citation: Reproductive Biology and Endocrinology 2020 18:11

    Content type: Review

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  32. Sexual health is strictly related with general health in both genders. In presence of a sexual dysfunction, the expert in sexual medicine aims to discover the specific weight of the physical and psychological ...

    Authors: Daniele Mollaioli, Giacomo Ciocca, Erika Limoncin, Stefania Di Sante, Giovanni Luca Gravina, Eleonora Carosa, Andrea Lenzi and Emmanuele Angelo Francesco Jannini

    Citation: Reproductive Biology and Endocrinology 2020 18:10

    Content type: Review

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  33. In young women with poor ovarian response, luteal-phase ovarian stimulation (LPOS) is a potential method for collecting competent oocytes. The aim of this study was to assess the efficacy of LPOS compared with...

    Authors: Joaquín Llácer, Belén Moliner, Lydia Luque, Andrea Bernabéu, Belén Lledó, Juan Carlos Castillo, Jaime Guerrero, Jorge Ten and Rafael Bernabéu

    Citation: Reproductive Biology and Endocrinology 2020 18:9

    Content type: Research

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  34. Congenital hypogonadotropic hypogonadism (CHH) is a rare disease, triggered by defective GnRH secretion, that is usually diagnosed in late adolescence or early adulthood due to the lack of spontaneous pubertal...

    Authors: Agnieszka Gach, Iwona Pinkier, Maria Szarras-Czapnik, Agata Sakowicz and Lucjusz Jakubowski

    Citation: Reproductive Biology and Endocrinology 2020 18:8

    Content type: Research

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  35. Poor response patients with PCOS who are not susceptible to gonadotropin stimulation are more likely to have canceled cycles or poor clinical outcomes during IVF treatment. However, some limitations exist in t...

    Authors: Bufang Xu, Mingjuan Zhou, Meiyu Cheng, Dan Zhang, Xian Wu, Chenchen Si, Lan Xia, Huihui Xu, Jian Li, Hsun-Ming Chang, Peter C. K. Leung and Aijun Zhang

    Citation: Reproductive Biology and Endocrinology 2020 18:7

    Content type: Research

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  36. LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can tr...

    Authors: Chao Lou, John L. Goodier and Rong Qiang

    Citation: Reproductive Biology and Endocrinology 2020 18:6

    Content type: Review

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  37. It is still one of the unresolved issues if germinal vesicle stage (GV) oocytes can be successfully cryopreserved for fertility preservation and matured in vitro without damage after warming. Several studies h...

    Authors: Dayong Lee, Hyang Heun Lee, Jung Ryeol Lee, Chang Suk Suh, Seok Hyun Kim and S. Samuel Kim

    Citation: Reproductive Biology and Endocrinology 2020 18:5

    Content type: Research

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  38. Human embryos are usually cultured to blastocyst stage by Day 5 or 6 after insemination. However, some embryos grow slowly and reach blastocyst stage at Day 7. Acceptable live birth rates have been reported af...

    Authors: Xiangli Niu, Cassie T. Wang, Richard Li, Ghassan Haddad and Weihua Wang

    Citation: Reproductive Biology and Endocrinology 2020 18:4

    Content type: Short communication

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  39. Only a few microbial studies have conducted in IVF (in vitro fertilization), showing the high-variety bacterial contamination of IVF culture media to cause damage to or even loss of cultured oocytes and embryo...

    Authors: Jelena Štšepetova, Juliana Baranova, Jaak Simm, Ülle Parm, Tiiu Rööp, Sandra Sokmann, Paul Korrovits, Madis Jaagura, Karin Rosenstein, Andres Salumets and Reet Mändar

    Citation: Reproductive Biology and Endocrinology 2020 18:3

    Content type: Research

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  40. Male fertility is multifaceted and its integrity is as well multifactorial. Normal spermatogenesis is dependent on competent testicular function; namely normal anatomy, histology, physiology and hormonal regul...

    Authors: Nermin I. Rizk, Mohamed S. Rizk, Asmaa S. Mohamed and Yahya M. Naguib

    Citation: Reproductive Biology and Endocrinology 2020 18:2

    Content type: Research

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  41. Controlled ovarian stimulation (COS) has a negative effect on the endometrial receptivity compared with natural menstrual cycle. Whether it’s necessary to postpone the first frozen embryo transfer (FET) follow...

    Authors: Yuxia He, Haiyan Zheng, Hongzi Du, Jianqiao Liu, Lei Li, Haiying Liu, Mingzhu Cao and Shiping Chen

    Citation: Reproductive Biology and Endocrinology 2020 18:1

    Content type: Research

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  42. Gestational diabetes mellitus (GDM) has a high prevalence in the period of pregnancy. However, the lack of gold standards in current screening and diagnostic methods posed the biggest limitation. Regulation of...

    Authors: Enchun Li, Tengfei Luo and Yingjun Wang

    Citation: Reproductive Biology and Endocrinology 2019 17:112

    Content type: Research

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  43. Previous studies of expression profiles of major endometrial effectors of steroid physiology in endometriosis have yielded markedly conflicting conclusions, presumably because the relative effects of type of e...

    Authors: G. Anupa, Jai Bhagwan Sharma, Kallol K. Roy, Jayasree Sengupta and Debabrata Ghosh

    Citation: Reproductive Biology and Endocrinology 2019 17:111

    Content type: Research

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  44. This article describes the research trends in sperm DNA fragmentation (SDF) over the past 20 years (1999–2018) using a scientometric approach.

    Authors: Saradha Baskaran, Ashok Agarwal, Manesh Kumar Panner Selvam, Renata Finelli, Kathy Amy Robert, Concetta Iovine, Peter Natesan Pushparaj, Luna Samanta, Avi Harlev and Ralf Henkel

    Citation: Reproductive Biology and Endocrinology 2019 17:110

    Content type: Research

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  45. Capacitation involves physiological changes that spermatozoa must undergo in the female reproductive tract or in vitro to obtain the ability to bind, penetrate and fertilize the egg. Up to date, several method...

    Authors: Lukas Ded, Pavla Dostalova, Eva Zatecka, Andrej Dorosh, Katerina Komrskova and Jana Peknicova

    Citation: Reproductive Biology and Endocrinology 2019 17:109

    Content type: Methodology

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  46. With the widely implementation of universal two-child policy, the number of pregnant women in advanced maternal age (AMA) will increase gradually. We aimed to assess the association of vitamin D levels and ins...

    Authors: Beibei Dong, Mengmeng Zhi, Manman Han, Hao Lin, Hong Yu and Ling Li

    Citation: Reproductive Biology and Endocrinology 2019 17:108

    Content type: Research

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