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Correction to: OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice

The Original Article was published on 26 June 2021

Correction to: Reprod Biol Endocrinol 19, 95 (2021)

https://doi.org/10.1186/s12958-021-00779-0

Following publication of the original article [1], the authors reported an error in Fig. 1. The published Fig. 1B is an image of mRNA RT-qPCR analysis of Otogl levels in developing testes, rather than a protein quantification analysis image as labeled. We have attached a corrected version of Fig. 1B.

The labels of F and G in the published Fig. 2 should be interchanged. This error does not change the scientific conclusions of the article in any way. The authors apologize for this error.

The correct figures are presented below.

Fig. 1
figure1

OTOGL is expressed in spermatogenic cells in mice. A RT-qPCR analyses of Otogl mRNA levels in nine organs of adult mice. B RT-qPCR analyses of Otogl mRNA levels in developing testes. Testes at postnatal Day 0 (P0), P7, P14, P21, P28, P35, and P56 were analyzed. Gapdh served as a loading control. C Western blotting shows the OTOGL protein levels in mouse testes at P0, P7, P14, P21, P28, P35, and P56. GAPDH served as a loading control. D Quantification analyses of OTOGL protein levels in developing testes at P0, P7, P14, P21, P28, P35, and P56. Data are presented as mean ± SD, n = 3

Fig. 2
figure2

OTOGL is nonessential for spermatogenesis in mice. A Schematic illustration of the targeting strategy for generating OTOGL deficiency in mouse testes. B The sequence of WT and Otogl KO alleles are shown, respectively. C Representative PCR genotyping results show that KO bands (669 bp) were detected larger than WT bands (472 bp). D Representative Western blot analysis of OTOGL protein levels in WT and KO adult testes. GAPDH served as a loading control. E RT-qPCR assays showing elevated Otogl mRNA levels in KO adult testes. Data are presented as mean ± SD, n = 3. *P < 0.01 by student’s t-test. F Average litter size of pups produced by Otogl KO and WT males mated with WT females. Data are presented as mean ± SD, n = 3. G Similar gross morphology of WT and Otogl KO testes. One unit on the ruler is 1mm. H Testis/body weight ratio of WT and Otogl KO adult testes. Data are presented as mean ± SD, n = 3

The original article [1] has been updated.

Reference

  1. 1.

    Li Z, Zhang Y, Zhang X, et al. OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice. Reprod Biol Endocrinol. 2021;19:95. https://doi.org/10.1186/s12958-021-00779-0.

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Correspondence to Yunge Tang or Shuiqiao Yuan.

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Li, Z., Zhang, Y., Zhang, X. et al. Correction to: OTOGL, a gelforming mucin protein, is nonessential for male germ cell development and spermatogenesis in mice. Reprod Biol Endocrinol 19, 136 (2021). https://doi.org/10.1186/s12958-021-00803-3

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