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  1. Research

    Cryopreservation and xenografting of human ovarian fragments: medulla decreases the phosphatidylserine translocation rate

    Phosphatidylserine is the phospholipid component which plays a key role in cell cycle signaling, specifically in regards to necrosis and apoptosis. When a cell affected by some negative factors, phosphatidylse...

    Vladimir Isachenko, Plamen Todorov, Evgenia Isachenko, Gohar Rahimi, Bettina Hanstein, Mahmoud Salama, Peter Mallmann, Andrey Tchorbanov, Paul Hardiman, Natalie Getreu and Markus Merzenich

    Reproductive Biology and Endocrinology 2016 14:79

    Published on: 10 November 2016

  2. Research

    Characterization of exosomal release in bovine endometrial intercaruncular stromal cells

    Cell-to-cell communication between the blastocyst and endometrium is critical for implantation. In recent years, evidence has emerged from studies in humans and several other animal species that exosomes are s...

    Yong Qin Koh, Hassendrini N. Peiris, Kanchan Vaswani, Sarah Reed, Gregory E. Rice, Carlos Salomon and Murray D. Mitchell

    Reproductive Biology and Endocrinology 2016 14:78

    Published on: 9 November 2016

  3. Research

    Efficient generation of GGTA1-null Diannan miniature pigs using TALENs combined with somatic cell nuclear transfer

    α1,3-Galactosyltransferase (GGTA1) is essential for the biosynthesis of glycoproteins and therefore a simple and effective target for disrupting the expression of galactose α-1,3-galactose epitopes, which medi...

    Wenmin Cheng, Heng Zhao, Honghao Yu, Jige Xin, Jia Wang, Luyao Zeng, Zaimei Yuan, Yubo Qing, Honghui Li, Baoyu Jia, Cejun Yang, Youfeng Shen, Lu Zhao, Weirong Pan, Hong-Ye Zhao, Wei Wang…

    Reproductive Biology and Endocrinology 2016 14:77

    Published on: 8 November 2016

  4. Research

    The participation of the muscarinic receptors in the preoptic-anterior hypothalamic areas in the regulation of ovulation depends on the ovary

    Muscarinic receptors (mAChRs) of the preoptic and anterior hypothalamus areas (POA-AHA) regulate ovulation in an asymmetric manner during the estrous cycle. The aims of the present study were to analyze the ef...

    Adriana Espinosa-Valdez, Angélica Flores, Isabel Arrieta-Cruz, Mario Cárdenas, Roberto Chavira, Roberto Domínguez and María Esther Cruz

    Reproductive Biology and Endocrinology 2016 14:75

    Published on: 4 November 2016

  5. Review

    Risk of adverse pregnancy and perinatal outcomes after high technology infertility treatment: a comprehensive systematic review

    In the literature, there is growing evidence that subfertile patients who conceived after infertility treatments have an increased risk of pregnancy and perinatal complications and this is particularly true fo...

    Stefano Palomba, Roy Homburg, Susanna Santagni, Giovanni Battista La Sala and Raoul Orvieto

    Reproductive Biology and Endocrinology 2016 14:76

    Published on: 4 November 2016

  6. Research

    Assisted reproductive technology pregnancy complications are significantly associated with endometriosis severity before conception: a retrospective cohort study

    Endometriosis has been shown to be associated with second- to third-trimester pregnancy complications such as preterm birth and placenta previa, but the evidence is inconsistent. We hypothesized that endometri...

    Tatsuya Fujii, Osamu Wada-Hiraike, Takeshi Nagamatsu, Miyuki Harada, Tetsuya Hirata, Kaori Koga, Tomoyuki Fujii and Yutaka Osuga

    Reproductive Biology and Endocrinology 2016 14:73

    Published on: 3 November 2016

  7. Research

    Biallelic modification of IL2RG leads to severe combined immunodeficiency in pigs

    Pigs with SCID can be a useful model in regenerative medicine, xenotransplantation, and cancer cell transplantation studies. Utilizing genome editing technologies such as CRISPR/Cas9 system allows us to genera...

    Jung-Taek Kang, Bumrae Cho, Junghyun Ryu, Caitlin Ray, Eun-Jin Lee, Yun-Jin Yun, SunMi Ahn, JinSeok Lee, Dal-Young Ji, Nathaniel Jue, Sherrie Clark-Deener, Kiho Lee and Kwang-Wook Park

    Reproductive Biology and Endocrinology 2016 14:74

    Published on: 3 November 2016

  8. Research

    Involvement of mesosalpinx in endometrioma is a possible risk factor for decrease of ovarian reserve after cystectomy: a retrospective cohort study

    Serum anti-Müllerian hormone (AMH) concentration has been used to assess ovarian reserve in patients with endometriosis, especially when endometrioma surgery is involved. Previously, we reported that decreased...

    Ai Saito, Akira Iwase, Tomoko Nakamura, Satoko Osuka, Bayasula, Tomohiko Murase, Nao Kato, Chiharu Ishida, Sachiko Takikawa, Maki Goto and Fumitaka Kikkawa

    Reproductive Biology and Endocrinology 2016 14:72

    Published on: 28 October 2016

  9. Research

    Second Harmonic Generation microscopy reveals collagen fibres are more organised in the cervix of postmenopausal women

    During labour, the cervix undergoes a series of changes to allow the passage of the fetoplacental unit. While this visible transformation is well-described, the underlying and causative microscopic changes, in...

    Brenda F. Narice, Nicola H. Green, Sheila MacNeil and Dilly Anumba

    Reproductive Biology and Endocrinology 2016 14:70

    Published on: 21 October 2016

  10. Research

    Local intra-uterine Ang-(1–7) infusion attenuates PGE2 and 6-keto PGF in decidualized uterus of pseudopregnant rats

    Cyclooxygenase (COX)-derived prostanoids (PGE2, PGI2) are important contributors to the process of decidualization. Previous studies showed the presence of Ang-(1-7) in the primary and secondary decidualized zone...

    K. Bridget Brosnihan, Victor M. Pulgar, Manish S. Bharadwaj, Liomar A. A. Neves and Liliya M. Yamaleyeva

    Reproductive Biology and Endocrinology 2016 14:68

    Published on: 18 October 2016

  11. Research

    Expression and regulation of ATF6α in the mouse uterus during embryo implantation

    ATF6α, one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum, is located in the membrane of the endoplasmic reticulum. To date, the physiological function of ATF6α in the proc...

    Yongjie Xiong, Wenzhe Li, Pengfei Lin, Lei Wang, Nan Wang, Fenglei Chen, Xiao Li, Aihua Wang and Yaping Jin

    Reproductive Biology and Endocrinology 2016 14:65

    Published on: 7 October 2016

  12. Research

    Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation

    Iatrogenic parasitic myomas (PMs), caused by intra-corporeal power morcellation during laparoscopy is gradually increasing. However, the pathogenesis and medical treatment of PMs remain largely unelucidated.

    Ben-Shian Huang, Muh-Hwa Yang, Peng-Hui Wang, Hsin-Yang Li, Teh-Ying Chou and Yi-Jen Chen

    Reproductive Biology and Endocrinology 2016 14:64

    Published on: 6 October 2016

  13. Research

    Whether G-CSF administration has beneficial effect on the outcome after assisted reproductive technology? A systematic review and meta-analysis

    Previous studies have explored the effect of granulocyte colony stimulating factor (G-CSF) administration on the outcome of assisted reproductive technology (ART), and came into controversial conclusions. The ...

    J. Zhao, B. Xu, S. Xie, Q. Zhang and Y. P. Li

    Reproductive Biology and Endocrinology 2016 14:62

    Published on: 22 September 2016

  14. Research

    Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease

    Adenomyosis is linked to infertility, but the mechanisms behind this relationship are not clearly established. Similarly, the impact of adenomyosis on ART outcome is not fully understood. Our main objective wa...

    J. M. Puente, A. Fabris, J. Patel, A. Patel, M. Cerrillo, A. Requena and J. A. Garcia-Velasco

    Reproductive Biology and Endocrinology 2016 14:60

    Published on: 20 September 2016

  15. Research

    Expressions of VEGF-A and VEGFR-2 in placentae from GDM pregnancies

    Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy, and has important health implications for mother and child. Changes in the fetoplacental vessels may predict th...

    Qian Meng, Li Shao, Xiucui Luo, Yingping Mu, Wen Xu, Li Gao, Haoqin Xu and Yugui Cui

    Reproductive Biology and Endocrinology 2016 14:61

    Published on: 20 September 2016

  16. Research

    Effects of platelet-rich plasma in a model of bovine endometrial inflammation in vitro

    Endometritis reduces fertility and is responsible for major economic losses in beef and dairy industries. The aim of this study was to evaluate an alternative therapy using platelet-rich plasma (PRP). PRP was ...

    Maria Giovanna Marini, Claudia Perrini, Paola Esposti, Bruna Corradetti, Davide Bizzaro, Pietro Riccaboni, Eleonora Fantinato, Giuseppe Urbani, Giorgio Gelati, Fausto Cremonesi and Anna Lange-Consiglio

    Reproductive Biology and Endocrinology 2016 14:58

    Published on: 13 September 2016

  17. Research

    Antioxidants reduce oxidative stress in follicular fluid of aged women undergoing IVF

    The status characterized by the imbalance between pro-oxidants and antioxidants molecules, defined as oxidative stress, has been suggested to be involved in the pathogenesis of subfertility in females. This st...

    Alice Luddi, Angela Capaldo, Riccardo Focarelli, Martina Gori, Giuseppe Morgante, Paola Piomboni and Vincenzo De Leo

    Reproductive Biology and Endocrinology 2016 14:57

    Published on: 7 September 2016

  18. Research

    Chronic effects of an anti-angiogenic thrombospondin-1 mimetic peptide, ABT-898, on female mouse reproductive outcomes

    Angiogenesis is an essential process in endometriosis disease progression. Earlier, we demonstrated that anti-angiogenic peptide, ABT-898 prevents neoangiogenesis of human endometriotic lesions in a xenograft ...

    Andrew K. Edwards, Irina Olariu, Diane S. Nakamura, Soo Hyun Ahn and Chandrakant Tayade

    Reproductive Biology and Endocrinology 2016 14:56

    Published on: 7 September 2016

  19. Short communication

    45,X product of conception after preimplantation genetic diagnosis and euploid embryo transfer: evidence of a spontaneous conception confirmed by DNA fingerprinting

    Preimplantation genetic screening (PGS) provides an opportunity to eliminate a potential implantation failure due to aneuploidy in infertile couples. Some studies clearly show that twins following single embry...

    Daniela Bettio, Antonio Capalbo, Elena Albani, Laura Rienzi, Valentina Achille, Anna Venci, Filippo Maria Ubaldi and Paolo Emanuele Levi Setti

    Reproductive Biology and Endocrinology 2016 14:55

    Published on: 6 September 2016

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