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  1. Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregn...

    Authors: Mike R. Wilson, Shannon Harkins, Jake J. Reske, Rebecca A. Siwicki, Marie Adams, Victoria L. Bae-Jump, Jose M. Teixeira and Ronald L. Chandler
    Citation: Reproductive Biology and Endocrinology 2023 21:43
  2. Women with functional hypothalamic amenorrhea (FHA) reveal polycystic ovarian morphology (PCOM) in up to 50%. If stress sensitivity in women with polycystic ovary syndrome (PCOS) is the reason why PCOS women a...

    Authors: Marlene Hager, Didier Dewailly, Rodrig Marculescu, Stefan Ghobrial, John Preston Parry and Johannes Ott
    Citation: Reproductive Biology and Endocrinology 2023 21:42
  3. To evaluate the association of serum advanced glycation end-products (AGEs) and its soluble receptor of AGE (sRAGE) levels with dysglycaemia and metabolic syndrome in women with polycystic ovary syndrome (PCOS).

    Authors: Yu Wing Tong, Jennifer Ka Yee Ko, Karen Siu Ling Lam, Sidney Tam, Vivian Chi Yan Lee, Pak Chung Ho, Ernest Hung Yu Ng and Raymond Hang Wun Li
    Citation: Reproductive Biology and Endocrinology 2023 21:41
  4. Studies have shown that sperm-borne microRNAs (miRNAs) are involved in mammalian preimplantation embryonic development. In humans, spermatozoan miR-34c levels are correlated with in vitro fertilization outcomes, ...

    Authors: Long Cui, Li Fang, Lili Zhuang, Biwei Shi, Chao-Po Lin and Yinghui Ye
    Citation: Reproductive Biology and Endocrinology 2023 21:40
  5. Several studies showed that human papillomavirus (HPV) affects male fertility, but its impact on female fertility and in vitro fertilization (IVF) outcome is not yet clear.

    Authors: Federica Zullo, Valentina Fiano, Anna Gillio-Tos, Sara Leoncini, Ginevra Nesi, Luigia Macrì, Mario Preti, Alessandro Rolfo, Chiara Benedetto, Alberto Revelli and Laura De Marco
    Citation: Reproductive Biology and Endocrinology 2023 21:39
  6. Ovarian aging is a process of decline in its reserve leading to ovary dysfunction and even reduced health quality in offspring. However, aging-related molecular pathways in the ovary remain obscure. Lysine suc...

    Authors: Meiling Le, Jia Li, Dalei Zhang, Yuan Yuan, Chong Zhou, Jinxia He, Jian Huang, Liaoliao Hu, Tao Luo and Liping Zheng
    Citation: Reproductive Biology and Endocrinology 2023 21:38
  7. Early embryo implantation is a complex phenomenon characterized by the presence of an implantation-competent blastocyst and a receptive endometrium. Embryo development and endometrial receptivity must be synch...

    Authors: Aurélie Hennes, Johanna Devroe, Katrien De Clercq, Martina Ciprietti, Katharina Held, Katrien Luyten, Nele Van Ranst, Nina Maenhoudt, Karen Peeraer, Hugo Vankelecom, Thomas Voets and Joris Vriens
    Citation: Reproductive Biology and Endocrinology 2023 21:37
  8. Retinoic acid (RA) plays important role in the maintenance and differentiation of the Müllerian ducts during the embryonic stage via RA receptors (RARs). However, the function and mechanism of RA-RAR signaling...

    Authors: Nana Zheng, Wenbo Zhang, Xiaodan Zhang, Biao Li, Zhanying Wu, Yashuang Weng, Weiyong Wang, Jingjing Miao, Jing Yang, Meijia Zhang and Wei Xia
    Citation: Reproductive Biology and Endocrinology 2023 21:36
  9. The pathogenesis of deep infiltrating endometriosis (DIE) is poorly understood. It is considered a benign disease but has histologic features of malignancy, such as local invasion or gene mutations. Moreover, ...

    Authors: A. Marshall, K. F. Kommoss, H. Ortmann, M. Kirchner, J. Jauckus, P. Sinn, T. Strowitzki and A. Germeyer
    Citation: Reproductive Biology and Endocrinology 2023 21:33
  10. DNAJBs are highly conserved proteins that are involved in various biological processes. Although several DNAJBs are highly expressed in the testis, the function of DNAJB7 in spermatogenesis and male fertility ...

    Authors: Shun Bai, Meihong Hu, Lina Yu, Linjun Chen, Jidong Zhou, Limin Wu, Bo Xu, Xiaohua Jiang, Xindong Zhang, Xianhong Tong and Qiuling Yue
    Citation: Reproductive Biology and Endocrinology 2023 21:32
  11. The predictive capability of time-lapse monitoring (TLM) selection algorithms is influenced by patient characteristics, type and quality of data included in the analysis and the used statistical methods. Previ...

    Authors: Eva S. van Marion, Esther B. Baart, Margarida Santos, Linette van Duijn, Evert J. P. van Santbrink, Régine P. M. Steegers-Theunissen, Joop S. E. Laven and Marinus J. C. Eijkemans
    Citation: Reproductive Biology and Endocrinology 2023 21:31
  12. Non-obstructive azoospermia (NOA) affects approximately 1% of the male population worldwide. The underlying mechanism and gene transcription remain unclear. This study aims to explore the potential pathogenesi...

    Authors: Yinwei Chen, Penghui Yuan, Longjie Gu, Jian Bai, Song Ouyang, Taotao Sun, Kang Liu, Zhao Wang and Chang Liu
    Citation: Reproductive Biology and Endocrinology 2023 21:30
  13. Granulocyte colony-stimulating factor (G-CSF) administration increased ovarian preantral follicles and anti-Müllerian hormone (AMH) in animal models with diminished ovarian reserve. We investigated whether G-C...

    Authors: Masao Jinno, Yukoku Tamaoka, Koji Teruya, Aiko Watanabe, Naohisa Hatakeyama, Tomoya Goda, Hayato Kimata and Yuichi Jinno
    Citation: Reproductive Biology and Endocrinology 2023 21:29
  14. Ovarian tissue transplantation can restore fertility in young cancer survivors, however the detrimental loss of follicles following transplantation of cryopreserved ovarian tissue is hampering the efficiency o...

    Authors: Hanna Ørnes Olesen, Susanne Elisabeth Pors, Cristina Subiran Adrados, Mette Christa Zeuthen, Linn Salto Mamsen, Anette Tønnes Pedersen and Stine Gry Kristensen
    Citation: Reproductive Biology and Endocrinology 2023 21:28
  15. Previous studies have demonstrated an association between male sperm quality and assisted reproduction outcomes, focusing on the effects of individual parameters and reaching controversial conclusions. The WHO...

    Authors: Tianwen Peng, Chen Liao, Xin Ye, Zhicong Chen, Xiaomin Li, Yu Lan, Xin Fu and Geng An
    Citation: Reproductive Biology and Endocrinology 2023 21:26
  16. After the longest time opposing all transfers of embryos by preimplantation genetic testing for aneuploidy (PGT-A) diagnosed as “chromosomal-abnormal,” the field has over recent years slowly been moving toward...

    Authors: Norbert Gleicher, Pasquale Patrizio, Lyka Mochizuki and David H. Barad
    Citation: Reproductive Biology and Endocrinology 2023 21:25
  17. Polycystic ovarian syndrome (PCOS) is one of the most common causes of infertility in reproductive-age women. However, the efficacy and optimal therapeutic strategy for reproductive outcomes are still under de...

    Authors: Ge Peng, Zhe Yan, Yuqi Liu, Juan Li, Jinfang Ma, Nanwei Tong and Yan Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:24
  18. Kallmann syndrome (KS) is a common type of idiopathic hypogonadotropic hypogonadism. To date, more than 30 genes including ANOS1 and FGFR1 have been identified in different genetic models of KS without affirmator...

    Authors: Guoming Chu, Pingping Li, Qian Zhao, Rong He and Yanyan Zhao
    Citation: Reproductive Biology and Endocrinology 2023 21:23
  19. Increasing evidence supports that the co-treatment with growth hormone (GH) enhances ovarian response and oocyte quality during controlled ovarian stimulation (COS) in patients with diminished ovarian reserve ...

    Authors: Fan He, Fang Wang, Yang Yang, Zhi Yuan, Chengguang Sun, Heng Zou, Huijia Chen, Hongliang Yi, Shan Hu Gao, Shen Zhang, Lina Hu and Ting-li Han
    Citation: Reproductive Biology and Endocrinology 2023 21:21
  20. Embryo implantation in a receptive endometrium is crucial for successful pregnancy. Endometrial receptivity (ER) prediction tools based on endometrial transcriptome biomarkers by endometrial biopsy have been u...

    Authors: Aihua He, Hong Wu, Yangyun Zou, Cheng Wan, Jing Zhao, Qiong Zhang, Nenghui Liu, Donge Liu, Yumei Li, Jing Fu, Hui Li, Xi Huang, Tianli Yang, Chunxu Hu, Zhaojuan Hou, Yue Sun…
    Citation: Reproductive Biology and Endocrinology 2023 21:20
  21. Ectopic pregnancy is more common amongst assisted reproduction cycles and is a cause of significant maternal morbidity. Few predictive markers exist to help identify and modify risk of ectopic pregnancy in pre...

    Authors: Kai-Lun Hu, Shan Li, Sarah Hunt, Rui Yang, Huiyu Xu and Rong Li
    Citation: Reproductive Biology and Endocrinology 2023 21:18
  22. Low vitamin D status has been associated with an increased risk for infertility. Recent evidence regarding the efficacy of vitamin D supplementation in improving reproductive outcomes is inconsistent. Therefor...

    Authors: Xiangqian Meng, Jiayao Zhang, Qi Wan, Jihua Huang, Tingting Han, Ting Qu and Lin-lin Yu
    Citation: Reproductive Biology and Endocrinology 2023 21:17
  23. Owing to its difficulty in degrading and ease of accumulation in the body, perfluorooctanoic acid (PFOA) has a detrimental effect on reproduction. This study aimed to examine the effect of PFOA concentration i...

    Authors: Haofei Shen, Min Gao, Qiuyuan Li, Huipeng Sun, Yingdi Jiang, Lihong Liu, Jingyuan Wu, Xiao Yu, Tianyu Jia, Yongan Xin, Shiqiang Han, Yiqing Wang and Xuehong Zhang
    Citation: Reproductive Biology and Endocrinology 2023 21:16
  24. This study aimed to evaluate the cut-off value of anti-Müllerian hormone (AMH) combined with body mass index (BMI) in the diagnosis of polycystic ovary syndrome (PCOS) and polycystic ovary morphology (PCOM).

    Authors: Menghui Zhang, Xiaocong Liu, Xiaolu Xu, Jing Li, Zhiqin Bu, Qingling Yang, Hao Shi, Wenbin Niu, Shanjun Dai, Yuling Liang and Yihong Guo
    Citation: Reproductive Biology and Endocrinology 2023 21:15
  25. Acromegaly is a disease of growth hormone excess that results in enlargement of extremities, abnormal glucose and lipid metabolism, and gonadal disruption. Manifestations of the disease are insidious and typic...

    Authors: Anamil M. Khiyami, Tahereh Orouji Jokar, Hussein M. Abdallah, Paul A. Gardner, Georgios A. Zenonos, Aaron K. Styer and Pouneh K. Fazeli
    Citation: Reproductive Biology and Endocrinology 2023 21:14
  26. Compaction is an important marker of embryonic genome activation and marks a critical step in the development to blastocyst. The objective of our study was to determine whether visualization of the embryonic c...

    Authors: Christine Hur, Vaani Nanavaty, Meng Yao and Nina Desai
    Citation: Reproductive Biology and Endocrinology 2023 21:12

    The Correction to this article has been published in Reproductive Biology and Endocrinology 2023 21:63

  27. Erectile dysfunction is a common problem in males of couples experiencing pregnancy loss. Erectile dysfunction in males with couple infertile has been extensively investigated and found to be closely linked wi...

    Authors: Xiaowei Yu, Songling Zhang, Xiao Yuan Zhang and Qun Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:11
  28. Metformin is the gold standard insulin sensitizer, which is widely used to treat insulin resistance in polycystic ovary syndrome (PCOS). However, metformin may induce gastrointestinal side effects.

    Authors: Dorina Greff, Anna E. Juhász, Szilárd Váncsa, Alex Váradi, Zoltán Sipos, Julia Szinte, Sunjune Park, Péter Hegyi, Péter Nyirády, Nándor Ács, Szabolcs Várbíró and Eszter M. Horváth
    Citation: Reproductive Biology and Endocrinology 2023 21:10
  29. Uterine leiomyomas (UL) are the most common benign tumor in women of reproductive age. Their pathology remains unclear, which hampers the development of safe and effective treatments. Raising evidence suggests...

    Authors: María Cristina Carbajo-García, Elena Juarez-Barber, Marina Segura-Benítez, Amparo Faus, Alexandra Trelis, Javier Monleón, Greta Carmona-Antoñanzas, Antonio Pellicer, James M. Flanagan and Hortensia Ferrero
    Citation: Reproductive Biology and Endocrinology 2023 21:9
  30. To construct prediction models based on the Bayesian network (BN) learning method for the probability of fertilization failure (including low fertilization rate [LRF] and total fertilization failure [TFF]) in ...

    Authors: Tian Tian, Fei Kong, Rui Yang, Xiaoyu Long, Lixue Chen, Ming Li, Qin Li, Yongxiu Hao, Yangbo He, Yunjun Zhang, Rong Li, Yuanyuan Wang and Jie Qiao
    Citation: Reproductive Biology and Endocrinology 2023 21:8
  31. Accumulating studies suggest that strict lockdown with enforcement including segregation to control the coronavirus disease 2019 (COVID-19) pandemic is associated with excess weight gain, but the such lockdown...

    Authors: Sho Tano, Tomomi Kotani, Takafumi Ushida, Yukako Iitani, Kenji Imai, Fumie Kinoshita and Hiroaki Kajiyama
    Citation: Reproductive Biology and Endocrinology 2023 21:7
  32. Human embryos express the prolactin (PRL) receptor at the morula and blastocyst stages. Treatment with PRL from cleavage to the blastocyst stage improves blastocyst outgrowth on fibronectin-coated dishes. Howe...

    Authors: Kenji Ezoe, Nanoha Fujiwara, Tetsuya Miki and Keiichi Kato
    Citation: Reproductive Biology and Endocrinology 2023 21:6
  33. Infertility affects one in every six couples in developed countries, and approximately 50% is of male origin. In 2021, sperm DNA fragmentation (SDF) testing became an evidence-based test for fertility evaluati...

    Authors: Anett Szabó, Szilárd Váncsa, Péter Hegyi, Alex Váradi, Attila Forintos, Teodóra Filipov, Júlia Ács, Nándor Ács, Tibor Szarvas, Péter Nyirády and Zsolt Kopa
    Citation: Reproductive Biology and Endocrinology 2023 21:5
  34. Emerging evidence of immunological dysfunction have been described in endometriosis. Dendritic cells (DCs), one of the main antigen-presenting cells, are specialized in the initiation and modulation of the ada...

    Authors: Zheng Qiaomei, Wu Ping, Zhao Yanjing, Wang Jinhua, Chen Shaozhan and Chen Lihong
    Citation: Reproductive Biology and Endocrinology 2023 21:4
  35. COVID-19 infection has been linked with erectile dysfunction, which has also raised apprehensions about the impact of COVID-19 vaccination on male sexual functions. The purpose of this study was to investigate...

    Authors: Poonam Mehta, Arijit Chakraborty, Syed Waseem Andrabi, Bhawani Sharma, Rakesh Kumar, L. V. K. S. Bhaskar and Singh Rajender
    Citation: Reproductive Biology and Endocrinology 2023 21:3
  36. Forty-six ,XY Differences/Disorders of Sex Development (DSD) are characterized by a broad phenotypic spectrum ranging from typical female to male with undervirilized external genitalia, or more rarely testicul...

    Authors: Khouloud Rjiba, Soumaya Mougou-Zerelli, Imen hadj Hamida, Ghada Saad, Bochra Khadija, Afef Jelloul, Wafa Slimani, Yosra Hasni, Sarra Dimassi, Hela Ben khelifa, Amira Sallem, Molka Kammoun, Hamza Hadj Abdallah, Moez Gribaa, Joelle Bignon-Topalovic, Sami Chelly…
    Citation: Reproductive Biology and Endocrinology 2023 21:2
  37. The exact role of sperm reactive oxygen species (ROS) in early embryo development has yet to be fully identified, and most of existing research did not differentiate female infertility factors, ignoring the im...

    Authors: Jin Liu, Keheng Zhu, Shiyan Xu, Wenjiao Tu, Xiaotan Lin, Youpeng Su, Rong Huang, Yuao Deng and Yu Liu
    Citation: Reproductive Biology and Endocrinology 2023 21:1
  38. There is a growing body of human, animal and in vitro studies on vitamin D (vit D) substitution in endometriosis. The aim of this systematic review is to critically appraise and qualitatively synthesize the resul...

    Authors: Dimitrios Rafail Kalaitzopoulos, Nicolas Samartzis, Angelos Daniilidis, Brigitte Leeners, Sofia Makieva, Konstantinos Nirgianakis, Ioannis Dedes, Julian Matthias Metzler, Patrick Imesch and Ioannis G. Lempesis
    Citation: Reproductive Biology and Endocrinology 2022 20:176
  39. The risk of hypertensive disorders of pregnancy (HDP) varies in women with gestational diabetes mellitus (GDM), depending on the degree of insulin resistance and is also influenced by obesity. The aim of this ...

    Authors: Almudena Lara-Barea, Begoña Sánchez-Lechuga, Manuel Aguilar-Diosdado and Cristina López-Tinoco
    Citation: Reproductive Biology and Endocrinology 2022 20:175
  40. Endometriosis is a chronic, inflammatory gynaecological disease that can have severe negative impacts on quality of life and fertility, placing burden on patients and the healthcare system. Due to the heterog...

    Authors: Simon Scheck, Emily S. J. Paterson and Claire E. Henry
    Citation: Reproductive Biology and Endocrinology 2022 20:174
  41. High-temperature requirement protease A2 (HtrA2/Omi) is a mitochondrial chaperone that is highly conserved from bacteria to humans. It plays an important role in mitochondrial homeostasis and apoptosis. In thi...

    Authors: Min Gao, Yanling Qiu, Tianqi Cao, Dungao Li, Jingwen Wang, Yiren Jiao, Zhiyun Chen and Junjiu Huang
    Citation: Reproductive Biology and Endocrinology 2022 20:173
  42. Authors: Liwei Yuan, Jia Cao, Mingyue Hu, Dabao Xu, Yan Li, Shiyun Zhao, Juanjuan Yuan, Huixing Zhang, Yani Huang, He Jin, Meixia Chen and Dan Liu
    Citation: Reproductive Biology and Endocrinology 2022 20:172

    The original article was published in Reproductive Biology and Endocrinology 2022 20:121

  43. Nowadays, patients attempting social/elective egg freezing has spread globally. Ovarian stimulation (OS) with high daily gonatotropin doses, are commonly offered to this group of patients, aiming to achieve th...

    Authors: Raoul Orvieto, Adva Aizer, Bozhena Saar-Ryss, Lilach Marom-Haham, Meirav Noach-Hirsh, Jigal Haas and Ravit Nahum
    Citation: Reproductive Biology and Endocrinology 2022 20:171
  44. The precise pathogenesis of poor endometrial receptivity in recurrent implantation failure (RIF) remains unclear. This study was aimed at exploring the effects of different CD44 isoforms in the mid-secretory p...

    Authors: Xiaowei Zhou, Yi Cao, Mingjuan Zhou, Mi Han, Mengyu Liu, Yanqin Hu, Bufang Xu and Aijun Zhang
    Citation: Reproductive Biology and Endocrinology 2022 20:170

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