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  1. Content type: Research

    Human epidemiological data show that breastfeeding reduces the mother’s probability of developing several disease conditions, including obesity and type II diabetes compared to mothers that give birth but do n...

    Authors: Hayden W. Hyatt, Yufeng Zhang, Wendy R. Hood and Andreas N. Kavazis

    Citation: Reproductive Biology and Endocrinology 2018 16:2

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  2. Content type: Research

    TGF-β signaling pathways regulate several crucial processes in female reproduction. AKT is a non-SMAD signaling pathway regulated by TGF-β ligands essential for oocyte maturation and early embryonic developmen...

    Authors: Mohamed Ashry, Sandeep K. Rajput, Joseph K. Folger, Jason G. Knott, Nabil A. Hemeida, Omaima M. Kandil, Refaat S. Ragab and George W. Smith

    Citation: Reproductive Biology and Endocrinology 2018 16:1

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  3. Content type: Research

    Plasma and urine levels of the potent vasodilator Ang-(1–7) are elevated in mid and late pregnancy and are correlated with elevated placental angiogenesis, fetal blood flow, and rapid fetal growth. We hypothes...

    Authors: Elham Ghadhanfar, Aseel Alsalem, Shaimaa Al-Kandari, Jumana Naser, Fawzi Babiker and Maie Al-Bader

    Citation: Reproductive Biology and Endocrinology 2017 15:97

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  4. Content type: Research

    Several studies have reported a correlation between antral follicle count by conventional 2D transvaginal sonography and serum anti-Müllerian hormone levels. However, few studies have investigated the effectiv...

    Authors: P. A. Peres Fagundes, R. Chapon, P. R. Olsen, A. K. Schuster, M. M. C. Mattia and J. S. Cunha-Filho

    Citation: Reproductive Biology and Endocrinology 2017 15:96

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  5. Content type: Research

    The published results regarding lymphocytes immunotherapy for unexplained recurrent miscarriage (uRM) patients are conflicting due to different screening criteria and therapeutic protocols. The objective of th...

    Authors: Mengyuan Liu, Xin Zhen, Hongyan Song, Junhao Chen, Xiaoling Sun, Xiaoqin Li, Jianjun Zhou, Guijun Yan, Lijun Ding and Haixiang Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:95

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  6. Content type: Review

    Polycystic ovary syndrome (PCOS) is a complex condition with high risk for dyslipidemia, dysglycemia, venous thromboembolism, cardiovascular disease and metabolic syndrome. Because the combined oral contracept...

    Authors: Sebastião Freitas de Medeiros

    Citation: Reproductive Biology and Endocrinology 2017 15:93

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  7. Content type: Research

    Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors. The aim of this study was to determine pot...

    Authors: Yang Gao, Xin Fang, David F. Vincent, David W. Threadgill, Laurent Bartholin and Qinglei Li

    Citation: Reproductive Biology and Endocrinology 2017 15:94

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  8. Content type: Short communication

    Recurrent pregnancy loss (RPL) is a frequently occurring disease, which is classified as idiopathic in more than 50% of cases. THBD, the endothelial cell receptor for thrombin, has been associated with distinc...

    Authors: Paula Quintero-Ronderos, Eric Mercier, Jean-Christophe Gris, Clara Esteban-Perez, Harold Moreno-Ortiz, Dora Janeth Fonseca, Elkin Lucena, Daniel Vaiman and Paul Laissue

    Citation: Reproductive Biology and Endocrinology 2017 15:92

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  9. Content type: Short communication

    We recently developed an air-liquid interface long-term culture of differentiated bovine oviductal epithelial cells (ALI-BOEC). This ex vivo oviduct epithelium is capable of supporting embryo development in co...

    Authors: Vera A. van der Weijden, Shuai Chen, Stefan Bauersachs, Susanne E. Ulbrich and Jennifer Schoen

    Citation: Reproductive Biology and Endocrinology 2017 15:91

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  10. Content type: Review

    Failure of embryo implantation is a major limiting factor in early pregnancy and assisted reproduction. Determinants of implantation include the embryo viability, the endometrial receptivity, and embryo-matern...

    Authors: Jingjie Liang, Shaoyu Wang and Zhengguang Wang

    Citation: Reproductive Biology and Endocrinology 2017 15:90

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  11. Content type: Research

    Ovulation and luteinization of follicles are complex biological processes initiated by the preovulatory luteinizing hormone surge. The objective of this study was to identify genes that are differentially expr...

    Authors: Jacques G. Lussier, Mame N. Diouf, Valérie Lévesque, Jean Sirois and Kalidou Ndiaye

    Citation: Reproductive Biology and Endocrinology 2017 15:88

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  12. Content type: Research

    Miscarriage is a common complication in pregnancy and there is still a lack of biomarkers usable in asymptomatic patients before the event occurs. Periostin (PER), whose levels rise particularly during injury ...

    Authors: A. Freis, J. Schlegel, R. J. Kuon, A. Doster, J. Jauckus, T. Strowitzki and A. Germeyer

    Citation: Reproductive Biology and Endocrinology 2017 15:87

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  13. Content type: Research

    Proper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during ...

    Authors: Huimin Xie, Hanne M. Hoffmann, Anita K. Iyer, Melissa J. Brayman, Cindy Ngo, Mary Jean Sunshine and Pamela L. Mellon

    Citation: Reproductive Biology and Endocrinology 2017 15:86

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  14. Content type: Research

    Recently, an effective testis culture method using a gas-liquid interphase, capable of differentiate male germ cells from neonatal spermatogonia to spermatozoa has been developed. Nevertheless, this methodolog...

    Authors: J. Isoler-Alcaraz, D. Fernández-Pérez, E. Larriba and J. del Mazo

    Citation: Reproductive Biology and Endocrinology 2017 15:85

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  15. Content type: Review

    Decidualization is an intricate biological process where extensive morphological, functional, and genetic changes take place in endometrial stromal cells to support the development of an implanting blastocyst....

    Authors: Nan Ni and Qinglei Li

    Citation: Reproductive Biology and Endocrinology 2017 15:84

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  16. Content type: Research

    Approximately half of recurrent miscarriages have unexplained etiology. Recent evidences suggest that cytokines are important determinants in pregnancy maintenance and as such, cytokine gene polymorphisms, whi...

    Authors: Jianting Ma, Xingguang Zhang, Gang He and Chunlin Yang

    Citation: Reproductive Biology and Endocrinology 2017 15:83

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  17. Content type: Correction

    After publication of the original article [1] it was noted that the caption of Table two was incorrect. This caption should read “Distribution of ovarian follicles depending on the type (healthy, transitional, an...

    Authors: Emilia Sinderewicz, Katarzyna Grycmacher, Dorota Boruszewska, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz, Tomasz Ślężak and Izabela Woclawek-Potocka

    Citation: Reproductive Biology and Endocrinology 2017 15:82

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    The original article was published in Reproductive Biology and Endocrinology 2017 15:72

  18. Content type: Research

    There are many variables affecting the onset of puberty in animals, including genetic, nutritional, and environmental factors. Recent studies suggest that epigenetic regulation, especially DNA methylation, pla...

    Authors: Lei Luo, Zhiqiu Yao, Jing Ye, Yuan Tian, Chen Yang, Xiaoxiao Gao, Min Song, Ya Liu, Yunhai Zhang, Yunsheng Li, Xiaorong Zhang and Fugui Fang

    Citation: Reproductive Biology and Endocrinology 2017 15:81

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  19. Content type: Research

    Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have be...

    Authors: Elia Fernandez Gallardo, Carl Spiessens, Thomas D’Hooghe and Sophie Debrock

    Citation: Reproductive Biology and Endocrinology 2017 15:79

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  20. Content type: Review

    Ooplasmic transfer (OT) technique or cytoplasmic transfer is an emerging technique with relative success, having a significant status in assisted reproduction. This technique had effectively paved the way to a...

    Authors: Sara Darbandi, Mahsa Darbandi, Hamid Reza Khorram Khorshid, Mohammad Reza Sadeghi, Ashok Agarwal, Pallav Sengupta, Safaa Al-Hasani and Mohammad Mehdi Akhondi

    Citation: Reproductive Biology and Endocrinology 2017 15:77

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  21. Content type: Research

    Embryo implantation is crucial for animal reproduction. Unsuccessful embryo implantation leads to pregnancy failure, especially in human-assisted conception. Environmental factors have a profound impact on emb...

    Authors: Lu Zhang, Zhenzhen Zhang, Feng Wang, Xiuzhi Tian, Pengyun Ji and Guoshi Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:78

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  22. Content type: Research

    Mechanical endometrial injury prior to IVF has been suggested as a means to increase implantation rates by improving endometrial receptivity. However, the effects of endometrial injury in proliferative vs. lut...

    Authors: Wenjie Liu, Reshef Tal, He Chao, Minghui Liu and Ying Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:75

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  23. Content type: Research

    Mural granulosa cells from IVF patients were provided by the West Virginia University Center for Reproductive Medicine in Morgantown, WV. The effect of adenosine monophosphate activated protein kinase (AMPK) a...

    Authors: E. C. Bowdridge, M. W. Vernon, J. A. Flores and M. J. Clemmer

    Citation: Reproductive Biology and Endocrinology 2017 15:76

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  24. Content type: Research

    Sperm cryopreservation is the most effective method to preserve male fertility but this is normally used for motile spermatozoa. Thus, only motile spermatozoa are used for cryopreservation in most reproductive...

    Authors: Huanhua Chen, Guixue Feng, Bo Zhang, Hong Zhou, Caizhu Wang, Jinhui Shu, Xianyou Gan, Ruoyun Lin, Dongmei Huang and Yingqin Huang

    Citation: Reproductive Biology and Endocrinology 2017 15:74

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  25. Content type: Research

    Lysophosphatidic acid (LPA) regulates reproductive processes in the cow. Ovarian granulosa cells play a pivotal role in follicle growth and development. Nevertheless, the role of LPA in the local regulation of...

    Authors: Emilia Sinderewicz, Katarzyna Grycmacher, Dorota Boruszewska, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz, Tomasz Ślężak and Izabela Woclawek-Potocka

    Citation: Reproductive Biology and Endocrinology 2017 15:72

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    The Correction to this article has been published in Reproductive Biology and Endocrinology 2017 15:82

  26. Content type: Review

    Uterine natural killer (uNK) cells are short-lived, terminally differentiated and the most abundant lymphocytes in the uterus which play a crucial role in the spiral arteriole modification and establishment of...

    Authors: Han Gong, Yilu Chen, Jingjie Xu, Xingxing Xie, Dainan Yu, Bei Yang and Haibin Kuang

    Citation: Reproductive Biology and Endocrinology 2017 15:73

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  27. Content type: Research

    The use of progestin (P) during ovarian stimulation is effective in blocking the luteinizing hormone (LH) surge in women with normal ovarian reserve, however, its effects have not been determined in poor respo...

    Authors: Qiuju Chen, Yun Wang, Lihua Sun, Shaozhen Zhang, Weiran Chai, Qingqing Hong, Hui Long, Li Wang, Qifeng Lyu and Yanping Kuang

    Citation: Reproductive Biology and Endocrinology 2017 15:71

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  28. Content type: Research

    For the last year we have been treating normal responders with gonadotropins and letrozole during the whole stimulation in order to improve response to FSH by increasing the intrafollicular androgen concentrat...

    Authors: Jigal Haas, Rawad Bassil, Jim Meriano, Nivin Samara, Eran Barzilay, Noa Gonen and Robert F. Casper

    Citation: Reproductive Biology and Endocrinology 2017 15:70

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  29. Content type: Research

    Polo-like kinase 1 (Plk1), as a characteristic regulator in meiosis, organizes multiple biological events of cell division. Although Plk1 has been implicated in various functions in somatic cell mitotic proces...

    Authors: Zixiao Zhang, Changchao Chen, Liying Ma, Qiuchen Yu, Shuai Li, Benazir Abbasi, Jiayi Yang, Rong Rui and Shiqiang Ju

    Citation: Reproductive Biology and Endocrinology 2017 15:69

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  30. Content type: Research

    Missed abortion is a common occurrence for otherwise healthy women. Immunological factor is one of the most important reasons. Tumor necrosis factor-α-induced protein-8 like-2 (TIPE2) is a novel negative immun...

    Authors: Yingshuo Sun, Xiaoyan Wang, Yue Li, Han Sun, Lu Wan, Xishuang Wang, Lining Zhang, Zhenghui Fang and Zengtao Wei

    Citation: Reproductive Biology and Endocrinology 2017 15:68

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  31. Content type: Research

    The World Health Organization (WHO) international body mass index (BMI) cut-off points defining pre-pregnancy BMI categories in the Institute of Medicine (IOM) guidelines are not directly applicable to Asians....

    Authors: Sae Kyung Choi, Guisera Lee, Yeon Hee Kim, In Yang Park, Hyun Sun Ko and Jong Chul Shin

    Citation: Reproductive Biology and Endocrinology 2017 15:67

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  32. Content type: Review

    The Catsper channel is a sperm-specific, Ca2+-permeable, pH-dependent, and low voltage-dependent channel that is essential for the hyperactivity of sperm flagellum, chemotaxis towards the egg, capacitation and ac...

    Authors: Xiang-hong Sun, Ying-ying Zhu, Lin Wang, Hong-ling Liu, Yong Ling, Zong-li Li and Li-bo Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:65

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  33. Content type: Research

    Endometrial cells secrete various cytokines and the dysfunction of endometrial cells may directly lead to infertility. Interferon tau (IFNT) secreted by trophoblast cells, a well-known pregnancy recognition si...

    Authors: Nao Tanikawa, Ayaka Ohtsu, Ryouka Kawahara-Miki, Koji Kimura, Shuichi Matsuyama, Hisataka Iwata, Takehito Kuwayama and Koumei Shirasuna

    Citation: Reproductive Biology and Endocrinology 2017 15:63

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  34. Content type: Research

    Ultrasound elastography is a non-invasive medical imaging technique able to quantitatively characterize the stiffness of a given tissue. It has been shown to predict the risk for cervical insufficiency and pre...

    Authors: Antonio Stanziano, Anna Maria Caringella, Clementina Cantatore, Giuseppe Trojano, Ettore Caroppo and Giuseppe D’Amato

    Citation: Reproductive Biology and Endocrinology 2017 15:64

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  35. Content type: Retraction Note

    Authors: Giovanni Battista La Sala, Alessia Nicoli, Eleonora Fornaciari, Angela Falbo, Ilaria Rondini, Daria Morini, Barbara Valli, Maria Teresa Villani and Stefano Palomba

    Citation: Reproductive Biology and Endocrinology 2017 15:62

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    The original article was published in Reproductive Biology and Endocrinology 2015 13:97

  36. Content type: Research

    Polycystic ovary syndrome (PCOS), whose aetiology is unknown, is predominately a familial syndrome but confirmation of candidate genes has proved elusive. The developmental hypothesis for the origin of PCOS su...

    Authors: Roy Homburg, Anil Gudi, Amit Shah and Alison M. Layton

    Citation: Reproductive Biology and Endocrinology 2017 15:61

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  37. Content type: Short communication

    We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospectiv...

    Authors: Sophie Pils, Natalia Stepien, Christine Kurz, Kazem Nouri, Regina Promberger and Johannes Ott

    Citation: Reproductive Biology and Endocrinology 2017 15:60

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  38. Content type: Research

    Bull fertility is the degree of sperm’s ability to fertilize and activate the egg and support embryo development, and this is critical for herd reproductive performance. We used the bull as a unique model orga...

    Authors: Naseer A. Kutchy, Ana Velho, Erika S. B. Menezes, Marie Jacobsen, Giselle Thibaudeau, Robert W. Wills, Arlindo Moura, Abdullah Kaya, Andy Perkins and Erdogan Memili

    Citation: Reproductive Biology and Endocrinology 2017 15:59

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  39. Content type: Research

    Human follicular fluid (HFF) provides a key environment for follicle development and oocyte maturation, and contributes to oocyte quality and in vitro fertilization (IVF) outcome.

    Authors: Xiaofang Shen, Xin Liu, Peng Zhu, Yuhua Zhang, Jiahui Wang, Yanwei Wang, Wenting Wang, Juan Liu, Ning Li and Fujun Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:58

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  40. Content type: Short Communication

    During negative energy balance, the concentration of different fatty acids, especially of oleic acid (OA) increases in the follicular fluid of cattle. Previously, we showed that OA induced morphological, physi...

    Authors: Vengala Rao Yenuganti and Jens Vanselow

    Citation: Reproductive Biology and Endocrinology 2017 15:57

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  41. Content type: Research

    We and others have observed that young girls predisposed to polycystic ovary syndrome (PCOS) display defective insulin sensitivity, beta-cell function and non-esterified fatty acids (NEFA) suppressibility during ...

    Authors: Soren Harnois-Leblanc, Andréanne Trottier, Samuel Leblanc, Marie-Claude Battista, David H. Geller and Jean-Patrice Baillargeon

    Citation: Reproductive Biology and Endocrinology 2017 15:56

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  42. Content type: Commentary

    According to the literature review, CO2 insufflation on parasitic myoma implantation is not well studied, and we concur that our study is related to “Morcellation-induced parasitic myomas.” We did not compare ...

    Authors: Ben-Shian Huang, Huann-Cheng Horng, Peng-Hui Wang, Muh-Hwa Yang and Yi-Jen Chen

    Citation: Reproductive Biology and Endocrinology 2017 15:55

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  43. Content type: Commentary

    The cause of contamination and dissemination of leiomyoma tissue particles and cells in the peritoneal cavity during myomectomy is a challenging issue for both clinicians and researchers. Therefore, the articl...

    Authors: Ospan A. Mynbaev, Antonio Malvasi, Sergei S. Simakov and Andrea Tinelli

    Citation: Reproductive Biology and Endocrinology 2017 15:54

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  44. Content type: Research

    We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to ev...

    Authors: Tomoko Hirakawa, Kaei Nasu, Yoko Aoyagi, Kanetoshi Takebayashi and Hisashi Narahara

    Citation: Reproductive Biology and Endocrinology 2017 15:53

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  45. Content type: Research

    Modeling early endometrial differentiation is a crucial step towards understanding the divergent pathways between normal and ectopic endometrial development as seen in endometriosis.

    Authors: P. Parasar, C. R. Sacha, N. Ng, E. R. McGuirk, S. Chinthala, P. Ozcan, J. Lindsey, S. Salas, M. R. Laufer, S. A. Missmer and R. M. Anchan

    Citation: Reproductive Biology and Endocrinology 2017 15:52

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  46. Content type: Research

    Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker...

    Authors: Yue-zhi Dong, Fei-jing Zhou and Ying-pu Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:51

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  47. Content type: Research

    Polycystic ovary syndrome is a complex disorder affecting 6 to 10% of women of reproductive age. In recent years, the cause of the syndrome has been associated with increased androgen serum levels, as well as ...

    Authors: Leticia Morales-Ledesma, Juan Antonio Díaz Ramos and Angélica Trujillo Hernández

    Citation: Reproductive Biology and Endocrinology 2017 15:50

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