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  1. Content type: Research

    Polo-like kinase 1 (Plk1), as a characteristic regulator in meiosis, organizes multiple biological events of cell division. Although Plk1 has been implicated in various functions in somatic cell mitotic proces...

    Authors: Zixiao Zhang, Changchao Chen, Liying Ma, Qiuchen Yu, Shuai Li, Benazir Abbasi, Jiayi Yang, Rong Rui and Shiqiang Ju

    Citation: Reproductive Biology and Endocrinology 2017 15:69

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  2. Content type: Research

    The World Health Organization (WHO) international body mass index (BMI) cut-off points defining pre-pregnancy BMI categories in the Institute of Medicine (IOM) guidelines are not directly applicable to Asians....

    Authors: Sae Kyung Choi, Guisera Lee, Yeon Hee Kim, In Yang Park, Hyun Sun Ko and Jong Chul Shin

    Citation: Reproductive Biology and Endocrinology 2017 15:67

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  3. Content type: Review

    The Catsper channel is a sperm-specific, Ca2+-permeable, pH-dependent, and low voltage-dependent channel that is essential for the hyperactivity of sperm flagellum, chemotaxis towards the egg, capacitation and ac...

    Authors: Xiang-hong Sun, Ying-ying Zhu, Lin Wang, Hong-ling Liu, Yong Ling, Zong-li Li and Li-bo Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:65

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  4. Content type: Research

    Endometrial cells secrete various cytokines and the dysfunction of endometrial cells may directly lead to infertility. Interferon tau (IFNT) secreted by trophoblast cells, a well-known pregnancy recognition si...

    Authors: Nao Tanikawa, Ayaka Ohtsu, Ryouka Kawahara-Miki, Koji Kimura, Shuichi Matsuyama, Hisataka Iwata, Takehito Kuwayama and Koumei Shirasuna

    Citation: Reproductive Biology and Endocrinology 2017 15:63

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  5. Content type: Research

    Ultrasound elastography is a non-invasive medical imaging technique able to quantitatively characterize the stiffness of a given tissue. It has been shown to predict the risk for cervical insufficiency and pre...

    Authors: Antonio Stanziano, Anna Maria Caringella, Clementina Cantatore, Giuseppe Trojano, Ettore Caroppo and Giuseppe D’Amato

    Citation: Reproductive Biology and Endocrinology 2017 15:64

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  6. Content type: Retraction Note

    Authors: Giovanni Battista La Sala, Alessia Nicoli, Eleonora Fornaciari, Angela Falbo, Ilaria Rondini, Daria Morini, Barbara Valli, Maria Teresa Villani and Stefano Palomba

    Citation: Reproductive Biology and Endocrinology 2017 15:62

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    The original article was published in Reproductive Biology and Endocrinology 2015 13:97

  7. Content type: Research

    Polycystic ovary syndrome (PCOS), whose aetiology is unknown, is predominately a familial syndrome but confirmation of candidate genes has proved elusive. The developmental hypothesis for the origin of PCOS su...

    Authors: Roy Homburg, Anil Gudi, Amit Shah and Alison M. Layton

    Citation: Reproductive Biology and Endocrinology 2017 15:61

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  8. Content type: Short communication

    We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospectiv...

    Authors: Sophie Pils, Natalia Stepien, Christine Kurz, Kazem Nouri, Regina Promberger and Johannes Ott

    Citation: Reproductive Biology and Endocrinology 2017 15:60

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  9. Content type: Research

    Bull fertility is the degree of sperm’s ability to fertilize and activate the egg and support embryo development, and this is critical for herd reproductive performance. We used the bull as a unique model orga...

    Authors: Naseer A. Kutchy, Ana Velho, Erika S. B. Menezes, Marie Jacobsen, Giselle Thibaudeau, Robert W. Wills, Arlindo Moura, Abdullah Kaya, Andy Perkins and Erdogan Memili

    Citation: Reproductive Biology and Endocrinology 2017 15:59

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  10. Content type: Research

    Human follicular fluid (HFF) provides a key environment for follicle development and oocyte maturation, and contributes to oocyte quality and in vitro fertilization (IVF) outcome.

    Authors: Xiaofang Shen, Xin Liu, Peng Zhu, Yuhua Zhang, Jiahui Wang, Yanwei Wang, Wenting Wang, Juan Liu, Ning Li and Fujun Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:58

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  11. Content type: Short Communication

    During negative energy balance, the concentration of different fatty acids, especially of oleic acid (OA) increases in the follicular fluid of cattle. Previously, we showed that OA induced morphological, physi...

    Authors: Vengala Rao Yenuganti and Jens Vanselow

    Citation: Reproductive Biology and Endocrinology 2017 15:57

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  12. Content type: Research

    We and others have observed that young girls predisposed to polycystic ovary syndrome (PCOS) display defective insulin sensitivity, beta-cell function and non-esterified fatty acids (NEFA) suppressibility during ...

    Authors: Soren Harnois-Leblanc, Andréanne Trottier, Samuel Leblanc, Marie-Claude Battista, David H. Geller and Jean-Patrice Baillargeon

    Citation: Reproductive Biology and Endocrinology 2017 15:56

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  13. Content type: Commentary

    According to the literature review, CO2 insufflation on parasitic myoma implantation is not well studied, and we concur that our study is related to “Morcellation-induced parasitic myomas.” We did not compare ...

    Authors: Ben-Shian Huang, Huann-Cheng Horng, Peng-Hui Wang, Muh-Hwa Yang and Yi-Jen Chen

    Citation: Reproductive Biology and Endocrinology 2017 15:55

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  14. Content type: Commentary

    The cause of contamination and dissemination of leiomyoma tissue particles and cells in the peritoneal cavity during myomectomy is a challenging issue for both clinicians and researchers. Therefore, the articl...

    Authors: Ospan A. Mynbaev, Antonio Malvasi, Sergei S. Simakov and Andrea Tinelli

    Citation: Reproductive Biology and Endocrinology 2017 15:54

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  15. Content type: Research

    We previously showed that microRNA-503 (miR-503) transfection into endometriotic cyst stromal cells (ECSCs) induced cell cycle arrest at the G0/G1 phase by suppressing cyclin D1. This finding prompted us to ev...

    Authors: Tomoko Hirakawa, Kaei Nasu, Yoko Aoyagi, Kanetoshi Takebayashi and Hisashi Narahara

    Citation: Reproductive Biology and Endocrinology 2017 15:53

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  16. Content type: Research

    Modeling early endometrial differentiation is a crucial step towards understanding the divergent pathways between normal and ectopic endometrial development as seen in endometriosis.

    Authors: P. Parasar, C. R. Sacha, N. Ng, E. R. McGuirk, S. Chinthala, P. Ozcan, J. Lindsey, S. Salas, M. R. Laufer, S. A. Missmer and R. M. Anchan

    Citation: Reproductive Biology and Endocrinology 2017 15:52

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  17. Content type: Research

    Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker...

    Authors: Yue-zhi Dong, Fei-jing Zhou and Ying-pu Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:51

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  18. Content type: Research

    Polycystic ovary syndrome is a complex disorder affecting 6 to 10% of women of reproductive age. In recent years, the cause of the syndrome has been associated with increased androgen serum levels, as well as ...

    Authors: Leticia Morales-Ledesma, Juan Antonio Díaz Ramos and Angélica Trujillo Hernández

    Citation: Reproductive Biology and Endocrinology 2017 15:50

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  19. Content type: Research

    The aim of this theoretical study is to explore the cost-effectiveness of aneuploidy screening in a UK setting for every woman aged under the age of 40 years when fresh and vitrified-warmed embryos are transfe...

    Authors: Paul N. Scriven

    Citation: Reproductive Biology and Endocrinology 2017 15:49

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  20. Content type: Review

    So-called mild controlled ovarian hyperstimulation (mCOH) has in recent years increased in popularity, claiming to be safer and more patient-friendly, while also improving in vitro fertilization (IVF) outcomes...

    Authors: Raoul Orvieto, Valeria Stella Vanni and Norbert Gleicher

    Citation: Reproductive Biology and Endocrinology 2017 15:48

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  21. Content type: Research

    The complex relationship between oocyte morphology, specific follicular fluid metabolites, gene expression in cumulus granulosa cells, and oocyte competence toward fertilization and embryo development still ne...

    Authors: Alberto Revelli, Stefano Canosa, Loredana Bergandi, Oleksii A. Skorokhod, Valentina Biasoni, Andrea Carosso, Angela Bertagna, Milena Maule, Elisabetta Aldieri, Maria Diletta D’Eufemia, Francesca Evangelista, Nicola Colacurci and Chiara Benedetto

    Citation: Reproductive Biology and Endocrinology 2017 15:47

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  22. Content type: Research

    The regulation of gonadotropin synthesis and release by gonadotropin­releasing hormone (GnRH) plays an essential role in the neuroendocrine control of reproduction. However, the mechanisms underlying gonadotro...

    Authors: Wei Xiang, Baoyun Zhang, Fenglin Lv, Guangde Feng, Long Chen, Fang Yang, Ke Zhang, Chunyu Cao, Pingqing Wang and Mingxing Chu

    Citation: Reproductive Biology and Endocrinology 2017 15:46

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  23. Content type: Research

    Anecdotal evidence suggests that US practice patterns for ART differ by geographical region. The purpose of this study was to determine whether use of ICSI differs by region and to evaluate whether these rates...

    Authors: Pavel Zagadailov, Albert Hsu, David B. Seifer and Judy E. Stern

    Citation: Reproductive Biology and Endocrinology 2017 15:45

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  24. Content type: Research

    The purpose of this study was to determine the utilization and live birth rates of assisted reproductive technology (ART) modalities among various racial and ethnic groups in recent years.

    Authors: Alice J. Shapiro, Sarah K. Darmon, David H. Barad, David F. Albertini, Norbert Gleicher and Vitaly A. Kushnir

    Citation: Reproductive Biology and Endocrinology 2017 15:44

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  25. Content type: Research

    The full maturational capability of mammalian oocytes is accompanied by nuclear and cytoplasmic modifications, which are associated with proliferation and differentiation of surrounding cumulus cells. These ev...

    Authors: Joanna Budna, Marta Rybska, Sylwia Ciesiółka, Artur Bryja, Sylwia Borys, Wiesława Kranc, Katarzyna Wojtanowicz-Markiewicz, Michal Jeseta, Ewa Sumelka, Dorota Bukowska, Paweł Antosik, Klaus P. Brüssow, Małgorzata Bruska, Michał Nowicki, Maciej Zabel and Bartosz Kempisty

    Citation: Reproductive Biology and Endocrinology 2017 15:43

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  26. Content type: Research

    A receptive endometrium is essential for maternal-embryonic molecular communication during implantation. However, the specific molecular regulatory mechanisms of the endometrial capacity remain poorly understo...

    Authors: Xi Cheng, Jingyu Liu, Huizhi Shan, Lihua Sun, Chenyang Huang, Qiang Yan, Ruiwei Jiang, Lijun Ding, Yue Jiang, Jianjun Zhou, Guijun Yan and Haixiang Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:42

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  27. Content type: Research

    Natriuretic peptides (NPs), brain and C type NPs (BNP and CNP), were involved in the maintenance of porcine oocyte meiotic arrest. The present study investigated the effects of NPs on developmental competence ...

    Authors: Yanhao Zhang, Huarong Wang, Wei Liu, Ye Yang, Xiao Wang, Zhiyuan Zhang, Qirui Guo, Chao Wang and Guoliang Xia

    Citation: Reproductive Biology and Endocrinology 2017 15:41

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  28. Content type: Research

    The 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (p,p’-DDT) is a known persistent organic pollutant and male reproductive toxicant. The present study is designed to test the hypothesis that oxidative stress m...

    Authors: Neila Marouani, Dorsaf Hallegue, Mohsen Sakly, Moncef Benkhalifa, Khémais Ben Rhouma and Olfa Tebourbi

    Citation: Reproductive Biology and Endocrinology 2017 15:40

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  29. Content type: Research

    Previous studies examining associations between subclinical hypothyroidism (SCH) with in vitro fertilization (IVF) outcome indicate some benefits of levothyroxine (LT4) treatment. But IVF outcomes in treated S...

    Authors: YunYing Cai, LanPing Zhong, Jie Guan, RuiJin Guo, Ben Niu, YanPing Ma and Heng Su

    Citation: Reproductive Biology and Endocrinology 2017 15:39

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  30. Content type: Review

    Premature ovarian insufficiency (POI) is a typical disorder of amenorrhea lasting for a minimum of 4 months. The typical characteristics comprised of declined estrogen and raised serum concentrations of follic...

    Authors: Ying Guo, Junyan Sun and Dongmei Lai

    Citation: Reproductive Biology and Endocrinology 2017 15:38

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  31. Content type: Research

    The aim of this study was to compare pregnancy rates in patients undergoing IVF/ICSI with embryo transfer after 4 and 5 days of culture in a closed incubation system with integrated time-lapse imaging.

    Authors: Verena Holschbach, Julia Weigert, Jens Erik Dietrich, Sabine Roesner, Markus Montag, Thomas Strowitzki and Bettina Toth

    Citation: Reproductive Biology and Endocrinology 2017 15:37

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  32. Content type: Review

    Comparative neonatal outcomes with respect to singleton births from blastocyst transfers or cleavage-state embryo transfers are controversial with respect to which method is superior. Many studies have yielded...

    Authors: Xingling Wang, Mingze Du, Yichun Guan, Bijun Wang, Junwei Zhang and Zihua Liu

    Citation: Reproductive Biology and Endocrinology 2017 15:36

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  33. Content type: Research

    Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory ho...

    Authors: Xinghui Han, Yuanyuan He, Gulan Zeng, Yonghong Wang, Wen Sun, Junchao Liu, Yanyan Sun and Jian Yu

    Citation: Reproductive Biology and Endocrinology 2017 15:35

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  34. Content type: Research

    Premutation range CGGn repeats of the FMR1 gene denote risk toward primary ovarian insufficiency (POI), also called premature ovarian failure (POF). This prospective cohort study was undertaken to determine if...

    Authors: David H. Barad, Sarah Darmon, Andrea Weghofer, Gary J. Latham, Filipovic-Sadic, Qi Wang, Vitaly A. Kushnir, David F. Albertini and Norbert Gleicher

    Citation: Reproductive Biology and Endocrinology 2017 15:34

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  35. Content type: Research

    It has become increasingly apparent that the trophectoderm (TE) at blastocyst stage is much more mosaic than has been appreciated. Whether preimplantation genetic screening (PGS), utilizing a single TE biopsy ...

    Authors: Norbert Gleicher, Jacob Metzger, Gist Croft, Vitaly A. Kushnir, David F. Albertini and David H Barad

    Citation: Reproductive Biology and Endocrinology 2017 15:33

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  36. Content type: Research

    The study is aimed to describe a novel strategy that increases the accuracy and reliability of PGD in patients using sperm donation by pre-selecting the donor whose haplotype does not overlap the carrier’s one.

    Authors: Mira Malcov, Veronica Gold, Sagit Peleg, Tsvia Frumkin, Foad Azem, Ami Amit, Dalit Ben-Yosef, Yuval Yaron, Adi Reches, Shimi Barda, Sandra E. Kleiman, Leah Yogev and Ron Hauser

    Citation: Reproductive Biology and Endocrinology 2017 15:31

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  37. Content type: Research

    In recent years, single blastocyst transfer combined with vitrification has been applied widely, which can maximize the cumulative pregnancy rate in per oocyte retrieval cycles and minimize the multiple pregna...

    Authors: Caizhu Wang, Guixue Feng, Bo Zhang, Hong Zhou, Jinhui Shu, Ruoyun Lin, Huanhua Chen and Zhulian Wu

    Citation: Reproductive Biology and Endocrinology 2017 15:32

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  38. Content type: Research

    The synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthe...

    Authors: Amilton Cesar dos Santos, Alan James Conley, Moacir Franco de Oliveira, Gleidson Benevides Oliveira, Diego Carvalho Viana and Antônio Chaves de Assis Neto

    Citation: Reproductive Biology and Endocrinology 2017 15:30

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  39. Content type: Research

    Currently, the cryopreservation of embryos and oocytes is essential for assisted reproductive technology (ART) laboratories worldwide. This study aimed to evaluate the efficacy of the Kitasato Vitrification Sy...

    Authors: Kenji Momozawa, Atsushi Matsuzawa, Yukio Tokunaga, Shiori Abe, Yumi Koyanagi, Miho Kurita, Marina Nakano and Takao Miyake

    Citation: Reproductive Biology and Endocrinology 2017 15:29

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  40. Content type: Research

    Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets. Antibodies against HPA-1a are acc...

    Authors: Mariana Eksteen, Gøril Heide, Heidi Tiller, Yan Zhou, Nora Hersoug Nedberg, Inigo Martinez-Zubiaurre, Anne Husebekk, Bjørn R. Skogen, Tor B. Stuge and Mette Kjær

    Citation: Reproductive Biology and Endocrinology 2017 15:28

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  41. Content type: Research

    The purpose of this study was to determine the mitochondrial content, and the oxidative and nitrosative stress of the placenta in women with gestational diabetes mellitus (GDM).

    Authors: Joel Ramírez-Emiliano, Martha E. Fajardo-Araujo, Ismael Zúñiga-Trujillo, Victoriano Pérez-Vázquez, Cuauhtémoc Sandoval-Salazar and Jessica K. Órnelas-Vázquez

    Citation: Reproductive Biology and Endocrinology 2017 15:26

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  42. Content type: Research

    Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal ...

    Authors: Chenyang Huang, Yue Jiang, Jianjun Zhou, Qiang Yan, Ruiwei Jiang, Xi Cheng, Jun Xing, Lijun Ding, Jianxin Sun, Guijun Yan and Haixiang Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:25

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  43. Content type: Research

    Repeat breeding directly affects reproductive efficiency in cattle due to an increase in services per conception and calving interval. This study aimed to investigate whether changes in endometrial gene expres...

    Authors: Ken-Go Hayashi, Misa Hosoe, Keiichiro Kizaki, Shiori Fujii, Hiroko Kanahara, Toru Takahashi and Ryosuke Sakumoto

    Citation: Reproductive Biology and Endocrinology 2017 15:20

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  44. Content type: Research

    Steroidogenesis is a complex, multi-steps biological process in which, cholesterol precursor is converted to steroids in a tissue specific and tropic hormone dependent manner. Given that steroidogenesis is ach...

    Authors: Jiaxin Li, Qian Zhou, Zhuang Ma, Meina Wang, Wen-Jun Shen, Salman Azhar, Zhigang Guo and Zhigang Hu

    Citation: Reproductive Biology and Endocrinology 2017 15:19

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