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  1. Content type: Review

    Asthenozoospermia is considered as a common cause of male infertility and characterized by reduced sperm motility. However, the molecular mechanism that impairs sperm motility remains unknown in most cases. In...

    Authors: Xiaodan Cao, Yun Cui, Xiaoxia Zhang, Jiangtao Lou, Jun Zhou, Huafeng Bei and Renxiong Wei

    Citation: Reproductive Biology and Endocrinology 2018 16:16

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  2. Content type: Research

    The LH-induced folliculo-luteal transformation is connected with alterations of the gene expression profile in cells of the granulosa layer. It has been described that hypoxic conditions occur during luteiniza...

    Authors: Anja Baufeld and Jens Vanselow

    Citation: Reproductive Biology and Endocrinology 2018 16:15

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  3. Content type: Research

    There exist contradictive views on whether the vitamin D has association with clinical outcome of in vitro fertilization (IVF) and/or intracytoplasmic sperm injection (ICSI). The present meta-analysis aim to e...

    Authors: Jing Zhao, Xi Huang, Bin Xu, Yi Yan, Qiong Zhang and Yanping Li

    Citation: Reproductive Biology and Endocrinology 2018 16:13

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  4. Content type: Research

    Forkhead Transcription Factor L2 (FOXL2) is a member of the forkhead family with important roles in reproduction. Recent studies showed that FOXL2 is expressed in human and bovine endometrium and that its leve...

    Authors: Michal Elbaz, Ron Hadas, Louise M. Bilezikjian and Eran Gershon

    Citation: Reproductive Biology and Endocrinology 2018 16:12

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  5. Content type: Short communication

    Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive disease with abnormalities in the structure of cilia, causing impairment of muco-ciliary clearance with respiratory tract infections, heterotaxia...

    Authors: Sinan Ozkavukcu, Ciler Celik-Ozenci, Esma Konuk and Cem Atabekoglu

    Citation: Reproductive Biology and Endocrinology 2018 16:10

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  6. Content type: Research

    Endometriosis is a known cause of infertility. Differences in immune tolerance caused by regulatory T cells (Tregs) and transforming growth factor-β (TGF-β) are thought to be involved in the pathology of endom...

    Authors: Tetsuro Hanada, Shunichiro Tsuji, Misako Nakayama, Shiro Wakinoue, Kyoko Kasahara, Fuminori Kimura, Takahide Mori, Kazumasa Ogasawara and Takashi Murakami

    Citation: Reproductive Biology and Endocrinology 2018 16:9

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  7. Content type: Research

    Cystatin C (CST3), a cysteine protease inhibitor in seminal plasma, is expressed in animal uteri. However, its expression in the human female reproductive tract and its effect on human sperm capacitation are u...

    Authors: Robert Kuo-Kuang Lee, Huan-Chin Tseng, Yuh-Ming Hwu, Chi-Chen Fan, Ming-Huei Lin, Jhih-Jie Yu, Ling-Yu Yeh and Sheng-Hsiang Li

    Citation: Reproductive Biology and Endocrinology 2018 16:8

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  8. Content type: Hypothesis

    Embryos have evolved a remarkable capacity to find implantation site. The impressive navigation ability of natural blastocysts may rely on highly sensitive signals arising from embryos and specialized signal p...

    Authors: Onder Celik, Mustafa Acet, Haldun Arpaci, Levent Dikbas, Aytac Imren, Bulent Duran, Nilufer Celik, Sudenaz Celik, Cihat Unlu, Ibrahim Sahin and Suleyman Aydin

    Citation: Reproductive Biology and Endocrinology 2018 16:7

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  9. Content type: Review

    L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of ...

    Authors: Ashok Agarwal, Pallav Sengupta and Damayanthi Durairajanayagam

    Citation: Reproductive Biology and Endocrinology 2018 16:5

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  10. Content type: Research

    Preimplantation genetic screening (PGS) is increasingly utilized as an adjunct procedure to IVF. Recently healthy euploid live birth were reported following transfer of mosaic embryos. Several recent publicati...

    Authors: Vitaly A. Kushnir, Sarah K. Darmon, David H. Barad and Norbert Gleicher

    Citation: Reproductive Biology and Endocrinology 2018 16:6

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  11. Content type: Research

    The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) and transcription factor (TF) expression may be involved in the pathogenesis and ...

    Authors: Luyang Zhao, Chenglei Gu, Mingxia Ye, Zhe Zhang, Li’an Li, Wensheng Fan and Yuanguang Meng

    Citation: Reproductive Biology and Endocrinology 2018 16:4

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  12. Content type: Review

    In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates an...

    Authors: Andrea Sansone, Carla Di Dato, Cristina de Angelis, Davide Menafra, Carlotta Pozza, Rosario Pivonello, Andrea Isidori and Daniele Gianfrilli

    Citation: Reproductive Biology and Endocrinology 2018 16:3

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  13. Content type: Research

    Human epidemiological data show that breastfeeding reduces the mother’s probability of developing several disease conditions, including obesity and type II diabetes compared to mothers that give birth but do n...

    Authors: Hayden W. Hyatt, Yufeng Zhang, Wendy R. Hood and Andreas N. Kavazis

    Citation: Reproductive Biology and Endocrinology 2018 16:2

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  14. Content type: Research

    TGF-β signaling pathways regulate several crucial processes in female reproduction. AKT is a non-SMAD signaling pathway regulated by TGF-β ligands essential for oocyte maturation and early embryonic developmen...

    Authors: Mohamed Ashry, Sandeep K. Rajput, Joseph K. Folger, Jason G. Knott, Nabil A. Hemeida, Omaima M. Kandil, Refaat S. Ragab and George W. Smith

    Citation: Reproductive Biology and Endocrinology 2018 16:1

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  15. Content type: Research

    Plasma and urine levels of the potent vasodilator Ang-(1–7) are elevated in mid and late pregnancy and are correlated with elevated placental angiogenesis, fetal blood flow, and rapid fetal growth. We hypothes...

    Authors: Elham Ghadhanfar, Aseel Alsalem, Shaimaa Al-Kandari, Jumana Naser, Fawzi Babiker and Maie Al-Bader

    Citation: Reproductive Biology and Endocrinology 2017 15:97

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  16. Content type: Research

    Several studies have reported a correlation between antral follicle count by conventional 2D transvaginal sonography and serum anti-Müllerian hormone levels. However, few studies have investigated the effectiv...

    Authors: P. A. Peres Fagundes, R. Chapon, P. R. Olsen, A. K. Schuster, M. M. C. Mattia and J. S. Cunha-Filho

    Citation: Reproductive Biology and Endocrinology 2017 15:96

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  17. Content type: Research

    The published results regarding lymphocytes immunotherapy for unexplained recurrent miscarriage (uRM) patients are conflicting due to different screening criteria and therapeutic protocols. The objective of th...

    Authors: Mengyuan Liu, Xin Zhen, Hongyan Song, Junhao Chen, Xiaoling Sun, Xiaoqin Li, Jianjun Zhou, Guijun Yan, Lijun Ding and Haixiang Sun

    Citation: Reproductive Biology and Endocrinology 2017 15:95

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  18. Content type: Review

    Polycystic ovary syndrome (PCOS) is a complex condition with high risk for dyslipidemia, dysglycemia, venous thromboembolism, cardiovascular disease and metabolic syndrome. Because the combined oral contracept...

    Authors: Sebastião Freitas de Medeiros

    Citation: Reproductive Biology and Endocrinology 2017 15:93

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  19. Content type: Research

    Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors. The aim of this study was to determine pot...

    Authors: Yang Gao, Xin Fang, David F. Vincent, David W. Threadgill, Laurent Bartholin and Qinglei Li

    Citation: Reproductive Biology and Endocrinology 2017 15:94

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  20. Content type: Short communication

    Recurrent pregnancy loss (RPL) is a frequently occurring disease, which is classified as idiopathic in more than 50% of cases. THBD, the endothelial cell receptor for thrombin, has been associated with distinc...

    Authors: Paula Quintero-Ronderos, Eric Mercier, Jean-Christophe Gris, Clara Esteban-Perez, Harold Moreno-Ortiz, Dora Janeth Fonseca, Elkin Lucena, Daniel Vaiman and Paul Laissue

    Citation: Reproductive Biology and Endocrinology 2017 15:92

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  21. Content type: Short communication

    We recently developed an air-liquid interface long-term culture of differentiated bovine oviductal epithelial cells (ALI-BOEC). This ex vivo oviduct epithelium is capable of supporting embryo development in co...

    Authors: Vera A. van der Weijden, Shuai Chen, Stefan Bauersachs, Susanne E. Ulbrich and Jennifer Schoen

    Citation: Reproductive Biology and Endocrinology 2017 15:91

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  22. Content type: Review

    Failure of embryo implantation is a major limiting factor in early pregnancy and assisted reproduction. Determinants of implantation include the embryo viability, the endometrial receptivity, and embryo-matern...

    Authors: Jingjie Liang, Shaoyu Wang and Zhengguang Wang

    Citation: Reproductive Biology and Endocrinology 2017 15:90

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