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  1. Cathepsin C (Cat C) is involved in the inflammatory-immune system and can be degraded by cathepsin D (Cat D). Preeclampsia (PE) and the inflammation-immunity relationship is currently a hot research topic, but...

    Authors: Jingzhe Song, Nan Zhu, Xinchen Pan, Lu Guo and Xiang Kong
    Citation: Reproductive Biology and Endocrinology 2023 21:92
  2. In human female primordial germ cells, the transition from mitosis to meiosis begins from the fetal stage. In germ cells, meiosis is arrested at the diplotene stage of prophase in meiosis I (MI) after synapsis...

    Authors: Zhenle Pei, Ke Deng, Congjian Xu and Shuo Zhang
    Citation: Reproductive Biology and Endocrinology 2023 21:90
  3. To evaluate the role of endometrial scratching performed prior to an embryo transfer cycle on the probability of pregnancy compared to placebo/sham or no intervention.

    Authors: Maria Chrysoula Iakovidou, Efstratios Kolibianakis, Leonidas Zepiridis and Christos Venetis
    Citation: Reproductive Biology and Endocrinology 2023 21:89
  4. Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in the degradation and recycling of cellular components. There is growing evidence that autophagy is related to male reproducti...

    Authors: Pourya Raee, Shing Cheng Tan, Sajad Najafi, Farshid Zandsalimi, Teck Yew Low, Shahin Aghamiri, Elham Fazeli, Mahyar Aghapour, Zahra Shams Mofarahe, Mohammad Hossein Heidari, Fatemeh Fadaei Fathabadi, Farid Abdi, Mohsen Asouri, Ali Asghar Ahmadi and Hossein Ghanbarian
    Citation: Reproductive Biology and Endocrinology 2023 21:88
  5. Studies show conflicting results on neonatal outcomes following embryo biopsy for PGT, primarily due to small sample sizes and/or heterogeneity in the timing of embryo biopsy (day 3; EBD3 or day 5/6; EBD5) and...

    Authors: Florence Belva, Fiskani Kondowe, Anick De Vos, Kathelijn Keymolen, Andrea Buysse, Frederik Hes, Veerle Berckmoes, Pieter Verdyck, Willem Verpoest and Martine De Rycke
    Citation: Reproductive Biology and Endocrinology 2023 21:87
  6. In a true-natural cycle (t-NC), optimal progesterone (P4) output from the corpus luteum is crucial for establishing and maintaining an intrauterine pregnancy. In a previous retrospective study, low P4 levels (< 1...

    Authors: Sezcan Mumusoglu, Murat Erden, Irem Yarali Ozbek, Onur Ince, Sandro C. Esteves, Peter Humaidan and Hakan Yarali
    Citation: Reproductive Biology and Endocrinology 2023 21:86
  7. Adhesion of the implanting blastocyst involves the interaction between integrin proteins expressed by trophoblast cells and components present in the basement membrane of the endometrial luminal epithelium. Al...

    Authors: Yuefei Lou, Laurie Pinel and Daniel Dufort
    Citation: Reproductive Biology and Endocrinology 2023 21:85
  8. While various endometrial biomarkers have been characterized at the transcriptomic and functional level, there is generally a poor overlap among studies, making it unclear to what extent their upstream regulat...

    Authors: Antonio Parraga-Leo, Patricia Sebastian-Leon, Almudena Devesa-Peiro, Diana Marti-Garcia, Nuria Pellicer, Jose Remohi, Francisco Dominguez and Patricia Diaz-Gimeno
    Citation: Reproductive Biology and Endocrinology 2023 21:84
  9. There was inconsistency in optimal endometrial preparation protocol for frozen-thawed embryo transfer (FET) in patients with endometriosis. We conducted this study to investigate the effect of different endome...

    Authors: Jingdi Yang, Yangxing Wen, Danping Li, Xuerong Hou, Bo Peng and Zengyan Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:83
  10. Actin-like 7 A (ACTL7A) is essential for acrosome formation, fertilization and early embryo development. ACTL7A variants cause acrosome detachment responsible for male infertility and early embryonic arrest. In t...

    Authors: Yini Zhang, Jianan Tang, Xuemei Wang, Yisi Sun, Tianying Yang, Xiaorong Shen, Xinyue Yang, Huijuan Shi, Xiaoxi Sun and Aijie Xin
    Citation: Reproductive Biology and Endocrinology 2023 21:82
  11. Thin endometrium is considered suboptimal for embryo implantation, leading to compromised pregnancy rates without effective therapies. While some studies have reported promoted endometrial growth after a perio...

    Authors: Jingjing Chen, Fangling Huang, Jing Fu, Jianjuan Zhao, Jinsheng Li, Zhengrong Peng, Jing Zhao, Bin Xu, Shuyi Li, Qiong Zhang, Shaolin Liang and Yanping Li
    Citation: Reproductive Biology and Endocrinology 2023 21:80
  12. Female infertility is a worldwide concern that impacts the quality of life and well-being of affected couples. Failure of embryo implantation is a major cause of early pregnancy loss and is precisely regulated...

    Authors: Xiaoling Liang, Xiaoxiao Qiu, Yana Ma, Wenzhi Xu, Sijia Chen, Peipei Zhang, Mengying Liu and Xiaona Lin
    Citation: Reproductive Biology and Endocrinology 2023 21:78
  13. Clinicians involved in fertility preservation (FP) are often required to make prompt and consequential decisions despite the absence of evidence-based data. We established a collaborative professional online c...

    Authors: Avi Tsafrir, Avi BenHaroush, Jordana Hyman, Gilad Karavani and Tal Imbar
    Citation: Reproductive Biology and Endocrinology 2023 21:77
  14. Diminished ovarian reserve (DOR) is a common cause of female infertility, with genetic factors being a significant contributor. However, due to high genetic heterogeneity, the etiology of DOR in many cases rem...

    Authors: Yingjing Wan, Zhidan Hong, Binyu Ma, Xuanyi He, Ling Ma, Mei Wang and Yuanzhen Zhang
    Citation: Reproductive Biology and Endocrinology 2023 21:76
  15. To systematically identify and narratively synthesize the evidence surrounding liposomal delivery of gene therapy and the outcome for ovarian cancer.

    Authors: Jin Sung Son, Ryan Chow, Helena Kim, Toney Lieu, Maria Xiao, Sunny Kim, Kathy Matuszewska, Madison Pereira, David Le Nguyen and Jim Petrik
    Citation: Reproductive Biology and Endocrinology 2023 21:75
  16. Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placen...

    Authors: Frantisek Staud, Xin Pan, Rona Karahoda, Xiaojing Dong, Petr Kastner, Hana Horackova, Veronika Vachalova, Udo R. Markert and Cilia Abad
    Citation: Reproductive Biology and Endocrinology 2023 21:74
  17. Artificial sweeteners, used as sugar substitutes have found their ways into almost all the food items due to the notion that they are non-caloric. Aspartame is used in numerous food products throughout the wor...

    Authors: Ab Qayoom Naik, Tabassum Zafar and Vinoy K Shrivastava
    Citation: Reproductive Biology and Endocrinology 2023 21:73
  18. To explore if exogenous progestin required for progestin primed ovarian stimulation (PPOS) protocol compromises the euploidy rate of patients who underwent preimplantation genetic testing cycles when compared ...

    Authors: Angel Hsin-Yu Pai, Yen Ju Sung, Chia-Jung Li, Chieh- Yu Lin and Chia Lin Chang
    Citation: Reproductive Biology and Endocrinology 2023 21:72
  19. Previous research suggests that some women are using integrative and complementary holistic approaches to optimize their own health and treat infertility. We aimed to determine patterns of integrative medicine...

    Authors: Shruti Sehgal, Ashley Dyer, Christopher Warren, Isabel Galic and Tarun Jain
    Citation: Reproductive Biology and Endocrinology 2023 21:71
  20. Polycystic ovarian syndrome (PCOS) is a widespread syndrome that poses unique challenges and constraints to the field of assisted reproductive technology. This condition is the most common cause of anovulation...

    Authors: Alexander M. Kotlyar and David B. Seifer
    Citation: Reproductive Biology and Endocrinology 2023 21:70
  21. Although psychoactive drugs have their therapeutic values, they have been implicated in the pathogenesis of male infertility. This study highlights psychoactive drugs reported to impair male fertility, their i...

    Authors: Moses Agbomhere Hamed, Victor Olukayode Ekundina and Roland Eghoghosoa Akhigbe
    Citation: Reproductive Biology and Endocrinology 2023 21:69
  22. Authors: Christos A. Venetis, Christoph Helwig, Ben W. Mol, Su Jen Chua, Salvatore Longobardi, Raoul Orvieto, Monica Lispi, Ashleigh Storr and Thomas D’Hooghe
    Citation: Reproductive Biology and Endocrinology 2023 21:68

    The original article was published in Reproductive Biology and Endocrinology 2021 19:51

  23. Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threating iatrogenic complication of the early luteal phase and/or early pregnancy after in vitro fertilization (IVF) treatment. The aim of the cu...

    Authors: Stefano Palomba, Flavia Costanzi, Scott M. Nelson, Donatella Caserta and Peter Humaidan
    Citation: Reproductive Biology and Endocrinology 2023 21:67
  24. The number of oocytes retrieved does not always coincide with the number of follicles aspirated in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment. Patients with high expectation o...

    Authors: Hao Jin, Haiyan Yang, Jiujia Zheng, Jiechun Zhou and Rong Yu
    Citation: Reproductive Biology and Endocrinology 2023 21:66
  25. Preeclampsia is a severe complication of pregnancy which is attributed to placental dysfunction. The retrotransposon, Paternal Expressed Gene 10 (PEG10) harbours critical placental functions pertaining to plac...

    Authors: Lydia Baird, Ping Cannon, Manju Kandel, Tuong-Vi Nguyen, Anna Nguyen, Georgia Wong, Cíara Murphy, Fiona C. Brownfoot, Elif Kadife, Natalie J. Hannan, Stephen Tong, Lucy A. Bartho and Tu’uhevaha J. Kaitu’u-Lino
    Citation: Reproductive Biology and Endocrinology 2023 21:65
  26. Assisted reproductive technology (ART) has brought good news to infertile patients, but how to improve the pregnancy outcome of poor ovarian response (POR) patients is still a serious challenge and the scienti...

    Authors: Fengya Zhu, Shao Yin, Bin Yang, Siyun Li, Xia Feng, Tianyu Wang and Deya Che
    Citation: Reproductive Biology and Endocrinology 2023 21:64
  27. Does a frozen-embryo transfer in an artificially-prepared endometrium (FET-HRT) cycle yield similar clinical pregnancy rate with 7 days of oestrogen priming compared to 14 days?

    Authors: Annalisa Racca, Samuel Santos-Ribeiro, Panagiotis Drakopoulos, Joran De Coppel, Lisbet Van Landuyt, Herman Tournaye and Christophe Blockeel
    Citation: Reproductive Biology and Endocrinology 2023 21:62
  28. Throughout the course of pregnancy, small maternal spiral arteries that are in contact with fetal tissue undergo structural remodeling, lose smooth muscle cells, and become less responsive to vasoconstrictors....

    Authors: Allan Kardec Nogueira Alencar, Kenneth F. Swan, Gabriella Pridjian, Sarah H. Lindsey and Carolyn L. Bayer
    Citation: Reproductive Biology and Endocrinology 2023 21:60
  29. Preeclampsia (PE), a pregnancy complication characterized by new-onset hypertension and proteinuria during the second trimester, is the leading cause of neonatal and maternal morbidity and mortality. In the et...

    Authors: Xiaotong Tang, Yueying Cao, Dan Wu, Lizhou Sun and Yetao Xu
    Citation: Reproductive Biology and Endocrinology 2023 21:58
  30. Unexplained recurrent spontaneous abortion (URSA) is one of the most challenging conditions frustrates women of childbearing age profoundly. The gene expression patterns and biological characteristics of place...

    Authors: Minyue Tang, Qingfang Li, Shan Wan, Qingqing Chen, Shujun Feng, Jiali You, Wei Wang and Yimin Zhu
    Citation: Reproductive Biology and Endocrinology 2023 21:57
  31. It has been hypothesized that the origin of early-onset endometriosis could be from endometrial mesenchymal stem cells (eMSCs) in neonatal uterine blood (NUB). There is no information on the possible mechanist...

    Authors: Kanae Ogawa, Khaleque N Khan, Haruo Kuroboshi, Akemi Koshiba, Koki Shimura, Tatsuro Tajiri, Shigehisa Fumino, Hiroyuki Fujita, Tomoharu Okubo, Yoichiro Fujiwara, Go Horiguchi, Satoshi Teramukai, Akira Fujishita, Kyoko Itoh, Sun-Wei Guo, Jo Kitawaki…
    Citation: Reproductive Biology and Endocrinology 2023 21:56
  32. This systematic review and meta-analysis aimed to explore the relationship of endometrial thickness (EMT) with obstetric and neonatal outcomes in assisted reproductive cycles.

    Authors: Zheng Fang, Jialyu Huang, Jiaqin Mao, Lamei Yu and Xiaohong Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:55
  33. In vitro fertilization-embryo transfer (IVF-ET) technologies (especially frozen ET) have been widely used, which might affect maternal and fetal health. Information regarding influence of IVF-ET on the vasocon...

    Authors: Jiaqi Tang, Linglu Qi, Yun He, Na Li, Ze Zhang, Xiuwen Zhou, Hongyu Su, Qiutong Zheng, Yumeng Zhang, Jianying Tao and Zhice Xu
    Citation: Reproductive Biology and Endocrinology 2023 21:54
  34. Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. Recently, several genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, W...

    Authors: Wantao Liu, Xinan Li, Qiang Ma, Yongtong Zhu, Wenzhong Zhao, Yisheng Yang, Weiqiang Xiao, Daxiong Huang, Fengbo Cai, David Yiu Leung Chan, Shanchao Zhao and Qingjun Chu
    Citation: Reproductive Biology and Endocrinology 2023 21:53
  35. Over the past decade, the application of frozen-thawed embryo transfer treatment cycles has increased substantially. Hormone replacement therapy and the natural cycle are two popular methods for preparing the ...

    Authors: Yiting Zhang, Xiao Fu, Shuli Gao, Shuzhe Gao, Shanshan Gao, Jinlong Ma and Zi-Jiang Chen
    Citation: Reproductive Biology and Endocrinology 2023 21:52
  36. Monozygotic twins (MZTs) are associated with high risks of maternal and fetal complications. Even with the widely used elective single embryo transfer (SET), the risk of MZTs following assisted reproductive te...

    Authors: Yubin Li, Qiyuan Chang and Qingyun Mai
    Citation: Reproductive Biology and Endocrinology 2023 21:51
  37. Decidual macrophages participate in immune regulation at the maternal–fetal interface. Abnormal M1/M2 polarization of decidual macrophages might predispose immune maladaptation in recurrent pregnancy loss (RPL...

    Authors: Yiyun Lou, Zhujing Fu, Ye Tian, Minhao Hu, Qijing Wang, Yuanyuan Zhou, Ning Wang, Qin Zhang and Fan Jin
    Citation: Reproductive Biology and Endocrinology 2023 21:50
  38. Artificial ovary (AO) is an alternative approach to provide physiological hormone to post-menopausal women. The therapeutic effects of AO constructed using alginate (ALG) hydrogels are limited by their low ang...

    Authors: Du Xiang, Encheng Zhou, Mei Wang, Kan Wang, Shujun Zhou, Qing Ma, Zibiao Zhong, Qifa Ye, Yun Chen, Xiaoli Fan and Yanfeng Wang
    Citation: Reproductive Biology and Endocrinology 2023 21:49
  39. Subfertility in obese and diabetic men during the reproductive age is evident, but the mechanisms by which obesity and diabetes mellitus cause male infertility are not entirely understood. The current study aimed...

    Authors: Shima AbbasiHormozi, Azam Kouhkan, Abdolhossein Shahverdi, Amir Parikar, Azin Shirin and Samira Vesali
    Citation: Reproductive Biology and Endocrinology 2023 21:48
  40. The key to optimal timing of frozen embryo transfer (FET ) is to synchronize the embryo with the receptive phase of the endometrium. Secretory transformation of the endometrium is induced by progesterone. In c...

    Authors: Carol Coughlan, Baris Ata, Raquel Del Gallego, Barbara Lawrenz, Laura Melado, Suzan Samir and Human Fatemi
    Citation: Reproductive Biology and Endocrinology 2023 21:47
  41. Efficient evaluation of the primordial follicle pool (PFP) of mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a ...

    Authors: Li Liu, Biting Liu, Lian Wang, Caixia Li, Yang Zhou, Jihui Zhu, Jinye Ding, Shupeng Liu and Zhongping Cheng
    Citation: Reproductive Biology and Endocrinology 2023 21:46
  42. To explore the efficacy and safety of individualized follitropin delta dosing, based on serum anti-Müllerian hormone (AMH) concentration and bodyweight, in a long gonadotropin-releasing hormone (GnRH) agonist ...

    Authors: Manuel Fernández Sánchez, Per Larsson, Marcos Ferrando Serrano, Ernesto Bosch, Juan Antonio García Velasco, Esther Santamaría López and Bernadette Mannaerts
    Citation: Reproductive Biology and Endocrinology 2023 21:45
  43. Online information about PCOS lacks reliability for patients seeking information about the disease. Thus, we aimed to perform an updated analysis of the quality, accuracy, and readability of patient informatio...

    Authors: Helene Vågenes and Shelly Melissa Pranić
    Citation: Reproductive Biology and Endocrinology 2023 21:44
  44. Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregn...

    Authors: Mike R. Wilson, Shannon Harkins, Jake J. Reske, Rebecca A. Siwicki, Marie Adams, Victoria L. Bae-Jump, Jose M. Teixeira and Ronald L. Chandler
    Citation: Reproductive Biology and Endocrinology 2023 21:43
  45. Women with functional hypothalamic amenorrhea (FHA) reveal polycystic ovarian morphology (PCOM) in up to 50%. If stress sensitivity in women with polycystic ovary syndrome (PCOS) is the reason why PCOS women a...

    Authors: Marlene Hager, Didier Dewailly, Rodrig Marculescu, Stefan Ghobrial, John Preston Parry and Johannes Ott
    Citation: Reproductive Biology and Endocrinology 2023 21:42

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