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  1. Cystic ovarian disease (COD) is an important cause of abnormal estrous behavior and infertility in dairy cows. COD is mainly observed in high-yielding dairy cows during the first months post-partum, a period o...

    Authors: Alfonso H Paredes, Natalia R Salvetti, Ariel E Diaz, Bibiana E Dallard, Hugo H Ortega and Hernan E Lara
    Citation: Reproductive Biology and Endocrinology 2011 9:66
    Content type: Research Published on:

  2. We describe the development of an electrochemical sensor array for monitoring the proliferation effects of cissus populnea plant extracts on TM4 Sertoli cells.

    Authors: Elizabeth Osibote, Naumih Noah, Omowunmi Sadik, Dennis McGee and Modupe Ogunlesi
    Citation: Reproductive Biology and Endocrinology 2011 9:65
    Content type: Methodology Published on:

  3. Placental hCG and pitutary LH transduce signals in target tissues through a common receptor (LHCGR). We demonstrate that recombinant LHCGR proteins which include the hormone-binding domain are secreted from tr...

    Authors: Anne E Chambers, Paul F Stanley, Harpal Randeva and Subhasis Banerjee
    Citation: Reproductive Biology and Endocrinology 2011 9:64
    Content type: Research Published on:

  4. PreImplantation Factor (PIF), a novel peptide secreted by viable embryos is essential for pregnancy: PIF modulates local immunity, promotes decidual pro-adhesion molecules and enhances trophoblast invasion. To...

    Authors: Christopher W Stamatkin, Roumen G Roussev, Mike Stout, Victor Absalon-Medina, Sivakumar Ramu, Chelsi Goodman, Carolyn B Coulam, Robert O Gilbert, Robert A Godke and Eytan R Barnea
    Citation: Reproductive Biology and Endocrinology 2011 9:63
    Content type: Research Published on:

  5. Although chicken oviduct is a useful model and target tissue for reproductive biology and transgenesis, little is known because of the highly specific hormonal regulation and the lack of fundamental researches...

    Authors: Jin Gyoung Jung, Whasun Lim, Tae Sub Park, Jin Nam Kim, Beom Ku Han, Gwonhwa Song and Jae Yong Han
    Citation: Reproductive Biology and Endocrinology 2011 9:62
    Content type: Research Published on:

  6. Menarche delay has been reported in adolescent females with type 1 diabetes (T1DM), perhaps due to poor glycemic control. We sought to compare age at menarche between adolescent females with T1DM and national ...

    Authors: Bahareh M Schweiger, Janet K Snell-Bergeon, Rossana Roman, Kim McFann and Georgeanna J Klingensmith
    Citation: Reproductive Biology and Endocrinology 2011 9:61
    Content type: Review Published on:

  7. Single blastocyst transfer has the advantage of maximizing the fresh single pregnancy rate. However, in patients with a low number of good quality embryos on day 3, it remains unclear whether immediate embryo ...

    Authors: Dominic Stoop, Lisbet Van Landuyt, Etienne Van den Abbeel, Michel Camus, Greta Verheyen and Paul Devroey
    Citation: Reproductive Biology and Endocrinology 2011 9:60
    Content type: Research Published on:

  8. It has been suggested that inhibin secretion is altered in women with the polycystic ovary syndrome (PCOS). However, the contribution of a preceding luteal phase has not been taken into account. The aim of the...

    Authors: Konstantinos Dafopoulos, Christos Venetis, Christina I Messini, Spyros Pournaras, George Anifandis, Antonios Garas and Ioannis E Messinis
    Citation: Reproductive Biology and Endocrinology 2011 9:59
    Content type: Research Published on:

  9. We compared two methods of zona pellucida drilling. 213 embryos were biopsied with acid Tyrode. Each biopsy took 3 minutes and the entire procedure ~29 minutes. 5% of blastomeres lysed, 49% of embryos became b...

    Authors: Selmo Geber, Renata Bossi, Cintia B Lisboa, Marcelo Valle and Marcos Sampaio
    Citation: Reproductive Biology and Endocrinology 2011 9:58
    Content type: Methodology Published on:

  10. The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in...

    Authors: David C Muller, Graham G Giles, Julie Bassett, Howard A Morris, John T Manning, John L Hopper, Dallas R English and Gianluca Severi
    Citation: Reproductive Biology and Endocrinology 2011 9:57
    Content type: Research Published on:

  11. PMP22, a member of the GAS3 family of tetraspan proteins, is associated with a variety of neurological diseases. Previous studies have shown that PMP22 is expressed in proliferative endometrium, but its functi...

    Authors: Rajiv G Rao, Deepthi Sudhakar, Claire P Hogue, Stephanie Amici, Lynn K Gordon, Jonathan Braun, Lucia Notterpek, Lee Goodglick and Madhuri Wadehra
    Citation: Reproductive Biology and Endocrinology 2011 9:56
    Content type: Research Published on:

  12. Sigmodontinae, known as "New World rats and mice," is a large subfamily of Cricetidae for which we herein provide the first comprehensive investigation of the placenta.

    Authors: Phelipe O Favaron, Anthony M Carter, Carlos E Ambrósio, Adriana C Morini, Andrea M Mess, Moacir F de Oliveira and Maria A Miglino
    Citation: Reproductive Biology and Endocrinology 2011 9:55
    Content type: Research Published on:

  13. Ovarian sex hormones (OSHs) are implicated in cardiovascular function. It has been shown that OSHs play an important role in the long term regulation of cardiac sarcoplasmic reticulum (SR) function and contrac...

    Authors: Altemar S Paigel, Rogerio F Ribeiro Junior, Aurelia A Fernandes, Gabriel P Targueta, Dalton V Vassallo and Ivanita Stefanon
    Citation: Reproductive Biology and Endocrinology 2011 9:54
    Content type: Research Published on:

  14. This study evaluated whether there is a relationship between the zona pellucida birefringence (ZP-BF) intensity and the nuclear (NM) and cytoplasmic (CM) in vitro maturation of human oocytes from stimulated cy...

    Authors: Claudia G Petersen, Laura D Vagnini, Ana L Mauri, Fabiana C Massaro, Liliane FI Silva, Mario Cavagna, Ricardo LR Baruffi, Joao BA Oliveira and José G Franco Jr
    Citation: Reproductive Biology and Endocrinology 2011 9:53
    Content type: Research Published on:

  15. Throughout oogenesis, cell-cell communication via gap junctions (GJs) between oocytes and surrounding follicle cells (theca and granulosa cells), and/or amongst follicle cells is required for successful follic...

    Authors: Yoji Yamamoto, J Adam Luckenbach, Mollie A Middleton and Penny Swanson
    Citation: Reproductive Biology and Endocrinology 2011 9:52
    Content type: Research Published on:

  16. Vascular endothelial growth factor receptor-2 (VEGFR2) plays a pivotal role in angiogenesis by eliciting vascular endothelial cell growth when bound to VEGF, a powerful pro-angiogenic ligand. While Vegf and Ve...

    Authors: Jonathan M Greene, Chad W Dunaway, Susan D Bowers, Brian J Rude, Jean M Feugang and Peter L Ryan
    Citation: Reproductive Biology and Endocrinology 2011 9:51
    Content type: Methodology Published on:

  17. NASP (Nuclear Autoantigenic Sperm Protein) is a histone chaperone that is present in all dividing cells. NASP has two splice variants: tNASP and sNASP. Only cancer, germ, transformed, and embryonic cells have ...

    Authors: Oleg M Alekseev, Richard T Richardson, James K Tsuruta and Michael G O'Rand
    Citation: Reproductive Biology and Endocrinology 2011 9:50
    Content type: Research Published on:

  18. Research on antimicrobial cationic peptides (AMPs) has gained pace toward using their potential to replace conventional antibiotics. These peptides preferentially interact with negatively charged membrane lipi...

    Authors: Jayasree Sengupta, Meraj Alam Khan, Berthold Huppertz and Debabrata Ghosh
    Citation: Reproductive Biology and Endocrinology 2011 9:49
    Content type: Research Published on:

  19. Pregnancy-associated plasma protein A2 (PAPPA2) is an insulin-like growth factor-binding protein (IGFBP) protease expressed at high levels in the placenta and upregulated in pregnancies complicated by preeclam...

    Authors: Pamela K Wagner, Aki Otomo and Julian K Christians
    Citation: Reproductive Biology and Endocrinology 2011 9:48
    Content type: Research Published on:

  20. There is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status. Detecting such damage in s...

    Authors: Nassira Zribi, Nozha Feki Chakroun, Henda Elleuch, Fatma Ben Abdallah, Afifa Sellami Ben Hamida, Jalel Gargouri, Faiza Fakhfakh and Leila Ammar Keskes
    Citation: Reproductive Biology and Endocrinology 2011 9:47
    Content type: Research Published on:

  21. Tribbles 3 (TRB3) affects insulin signalling by inhibiting insulin-stimulated Akt phosphorylation and subsequent activation. A single nucleotide polymorphism located in the second extron of the human TRB3 gene...

    Authors: Xue Zhang, Li Fu, Qiufang Zhang, Liying Yan, Yanmin Ma, Binbin Tu, Nana Liu and Jie Qiao
    Citation: Reproductive Biology and Endocrinology 2011 9:46
    Content type: Research Published on:

  22. Large volumes of lymph can be collected from the eye-sacs of bubble-eye goldfish. We attempted to induce vitellogenin (Vtg) in the eye-sac lymph of bubble-eye goldfish and develop a method for visualizing Vtg ...

    Authors: Yohei Matsuda, Yoshie Ito, Hisashi Hashimoto, Hayato Yokoi and Tohru Suzuki
    Citation: Reproductive Biology and Endocrinology 2011 9:45
    Content type: Methodology Published on:

  23. Authors: Amelie Fassbender, Peter Simsa, Cleophas M Kyama, Etienne Waelkens, Attila Mihalyi, Christel Meuleman, Olivier Gevaert, Raf Van de Plas, Bart de Moor and Thomas M D'Hooghe
    Citation: Reproductive Biology and Endocrinology 2011 9:44
    Content type: Erratum Published on:

    The original article was published in Reproductive Biology and Endocrinology 2010 8:123

  24. Proprotein convertase 5/6 (PC5/6) is critical for embryo implantation in women, regulating both uterine epithelial receptivity and stromal cell decidualization. PC5/6 is likewise essential for implantation in ...

    Authors: Peter K Nicholls, Zhaogui Sun, Sophea Heng, Ying Li, Jian Wang and Guiying Nie
    Citation: Reproductive Biology and Endocrinology 2011 9:43
    Content type: Research Published on:

  26. In the present study we analyzed the existence of asymmetry in the secretion of steroid hormones in pre-pubertal female rats treated with unilateral ovariectomy (ULO) or unilateral perforation of the abdominal...

    Authors: Leticia Morales-Ledesma, Deyra A Ramírez, Elizabeth Vieyra, Angélica Trujillo, Roberto Chavira, Mario Cárdenas and Roberto Domínguez
    Citation: Reproductive Biology and Endocrinology 2011 9:41
    Content type: Methodology Published on:

  27. Nucleoplasmin 2 (NPM2) is an oocyte-specific nuclear protein essential for nuclear and nucleolar organization and early embryonic development. The aims of this study were to clone the bovine NPM2 gene, determine ...

    Authors: Brandon M Lingenfelter, Swamy K Tripurani, Jyothsna Tejomurtula, George W Smith and Jianbo Yao
    Citation: Reproductive Biology and Endocrinology 2011 9:40
    Content type: Research Published on:

  28. Despite the heavy burden and impact of the polycystic ovary syndrome (PCOS) in reproduction and public health, estimates regarding its prevalence at community levels are limited. We aimed to ascertain prevalen...

    Authors: Fahimeh Ramezani Tehrani, Masoumeh Simbar, Maryam Tohidi, Farhad Hosseinpanah and Fereidoun Azizi
    Citation: Reproductive Biology and Endocrinology 2011 9:39
    Content type: Research Published on:

  29. SERPINE2, also known as protease nexin-1, belongs to the serine protease inhibitor (SERPIN) superfamily. It is one of the potent SERPINs that modulates the activity of plasminogen activators (PAs). PAs and the...

    Authors: Robert Kuo-Kuang Lee, Chi-Chen Fan, Yuh-Ming Hwu, Chung-Hao Lu, Ming-Huei Lin, Ying-Jie Chen and Sheng-Hsiang Li
    Citation: Reproductive Biology and Endocrinology 2011 9:38
    Content type: Research Published on:

  30. Fertilization, cell division and embryo development depend on genomic contributions from male and female gametes. We hypothesize that teratozoospermic sperm influences early embryo development and embryo compa...

    Authors: Dara S Berger, Faten AbdelHafez, Helena Russell, James Goldfarb and Nina Desai
    Citation: Reproductive Biology and Endocrinology 2011 9:37
    Content type: Research Published on:

  31. Male-factor infertility presents a vexing problem for many reproductively active couples. Many studies have focused on abnormal sperm parameters. Recent advances in proteomic techniques, especially in mass spe...

    Authors: Stefan S du Plessis, Anthony H Kashou, David J Benjamin, Satya P Yadav and Ashok Agarwal
    Citation: Reproductive Biology and Endocrinology 2011 9:36
    Content type: Review Published on:

  32. Potassium channels play critical roles in the regulation of cell membrane potential, which is central to the excitability of myometrium. The ATP-sensitive potassium (KATP) channel is one of the most abundant p...

    Authors: Chen Xu, Xingji You, Lu Gao, Lanmei Zhang, Rong Hu, Ning Hui, David M Olson and Xin Ni
    Citation: Reproductive Biology and Endocrinology 2011 9:35
    Content type: Research Published on:

  33. The present study analyzed the participation of the left and right superior ovarian nerves (SON) in regulating progesterone, testosterone, and estradiol serum levels in unilaterally ovariectomized rats on each...

    Authors: Angélica Flores, Jacqueline Velasco, Alma I Gallegos, Fernando D Mendoza, Pamela M Everardo, María-Esther Cruz and Roberto Domínguez
    Citation: Reproductive Biology and Endocrinology 2011 9:34
    Content type: Research Published on:

  34. It has been reported that calf oocytes are less developmentally competent than oocytes obtained from adult cows. Bone morphogenetic protein 15 (BMP15) and growth and differentiation factor 9 (GDF9) play critic...

    Authors: Misa Hosoe, Kanako Kaneyama, Koichi Ushizawa, Ken-go Hayashi and Toru Takahashi
    Citation: Reproductive Biology and Endocrinology 2011 9:33
    Content type: Research Published on:

  35. Obesity is rapidly becoming a worldwide epidemic that affects children and adults. Some studies have shown a relationship between obesity and infertility, but until now it remains controversial. Thus, the aim ...

    Authors: Carla DB Fernandez, Fernanda F Bellentani, Glaura SA Fernandes, Juliana E Perobelli, Ana Paula A Favareto, André F Nascimento, Antonio C Cicogna and Wilma DG Kempinas
    Citation: Reproductive Biology and Endocrinology 2011 9:32
    Content type: Research Published on:

  36. European bison is the largest mammal in Europe with the population of approximately 4000 individuals. However, there is no report of post-mortem spermatozoa collection and cryopreservation from this species an...

    Authors: Roland Kozdrowski, Wojciech Niżański, Andrzej Dubiel and Wanda Olech
    Citation: Reproductive Biology and Endocrinology 2011 9:31
    Content type: Methodology Published on:

  37. Adenomyosis is a common gynecological disease, which is accompanied by a series of immunological and neuroendocrinological changes. Nerve growth factor (NGF) plays a critical role in producing pain, neural pla...

    Authors: Yan Li, Shao-fen Zhang, Shi-en Zou, Xian Xia and Lei Bao
    Citation: Reproductive Biology and Endocrinology 2011 9:30
    Content type: Research Published on:

  39. Human endometrium resists embryo implantation except during the 'window of receptivity'. A change in endometrial gene expression is required for the development of receptivity. Uterine calbindin-D28k (CaBP-28k...

    Authors: Hyun Yang, Tae-Hee Kim, Hae-Hyeog Lee, Kyung-Chul Choi, Yeon-pyo Hong, Peter CK Leung and Eui-Bae Jeung
    Citation: Reproductive Biology and Endocrinology 2011 9:28
    Content type: Research Published on:

  40. The interactions between luteal, vascular endothelial, immune cells and its products: steroids, peptide hormones, prostaglandins (PGs), growth factors and cytokines play a pivotal role in the regulation of cor...

    Authors: Anna J Korzekwa, Gabriel Bodek, Joanna Bukowska, Agnieszka Blitek and Dariusz J Skarzynski
    Citation: Reproductive Biology and Endocrinology 2011 9:27
    Content type: Research Published on:

  41. In male patients suffering from chronic pain, opioid administration induces severe hypogonadism, leading to impaired physical and psychological conditions such as fatigue, anaemia and depression. Hormone repla...

    Authors: Anna Maria Aloisi, Ilaria Ceccarelli, Maria Carlucci, Annalisa Suman, Gianfranco Sindaco, Sergio Mameli, Valentina Paci, Laura Ravaioli, Giandomenico Passavanti, Valeria Bachiocco and Gilberto Pari
    Citation: Reproductive Biology and Endocrinology 2011 9:26
    Content type: Research Published on:

  42. In the last decades, several steps have been made aiming at rendering human IVF more successful on one side, more tolerable on the other side. The "mild" ovarian stimulation approach, in which a lower-than-ave...

    Authors: Alberto Revelli, Simona Casano, Francesca Salvagno and Luisa Delle Piane
    Citation: Reproductive Biology and Endocrinology 2011 9:25
    Content type: Review Published on:

  43. The objective of the present study was to isolate and purify the protein fraction(s) of llama seminal plasma responsible for the ovulation-inducing effect of the ejaculate.

    Authors: Marcelo H Ratto, Louis TJ Delbaere, Yvonne A Leduc, Roger A Pierson and Gregg P Adams
    Citation: Reproductive Biology and Endocrinology 2011 9:24
    Content type: Research Published on:

  44. Though a widely utilized term and clinical concept, ovarian reserve (OR) has been only inadequately defined. Based on Medline and PubMed searches we here define OR in its various components, review genetic con...

    Authors: Norbert Gleicher, Andrea Weghofer and David H Barad
    Citation: Reproductive Biology and Endocrinology 2011 9:23
    Content type: Review Published on:

  45. We have previously demonstrated that four members of the family of small leucine-rich-proteoglycans (SLRPs) of the extracellular matrix (ECM), named decorin, biglycan, lumican and fibromodulin, are deeply remo...

    Authors: Renato M Salgado, Rodolfo R Favaro and Telma MT Zorn
    Citation: Reproductive Biology and Endocrinology 2011 9:22
    Content type: Research Published on:

  46. Some adult stem cells persist in adult tissue; however, we do not know how to stimulate stem cells in adults to heal injuries. Liver growth factor (LGF) is a biliprotein with hepatic mitogen activity. Its conc...

    Authors: Miriam Pérez-Crespo, Eva Pericuesta, Serafín Pérez-Cerezales, Maria I Arenas, Maria VT Lobo, Juan J Díaz-Gil and Alfonso Gutierrez-Adan
    Citation: Reproductive Biology and Endocrinology 2011 9:21
    Content type: Methodology Published on:

  47. In higher primates, although LH/CG play a critical role in the control of corpus luteum (CL) function, the direct effects of progesterone (P4) in the maintenance of CL structure and function are unclear. Sever...

    Authors: Padmanaban S Suresh, Kadthur C Jayachandra and Rudraiah Medhamurthy
    Citation: Reproductive Biology and Endocrinology 2011 9:20
    Content type: Research Published on:

  48. The clinical results of in vitro fertilization of slowly frozen-thawed oocytes are known to be significantly worse than those obtained by fresh oocytes. Little is known about the factors affecting the clinical ou...

    Authors: Irma Virant-Klun, Liljana Bacer-Kermavner, Tomaz Tomazevic and Eda Vrtacnik-Bokal
    Citation: Reproductive Biology and Endocrinology 2011 9:19
    Content type: Research Published on:

  49. BMP4 is a member of the transforming growth factor beta (TGFbeta) superfamily and Noggin is a potent BMP inhibitor that exerts its function by binding to BMPs preventing interactions with its receptors. The ai...

    Authors: Isabel La Rosa, Luiz SA Camargo, Michele M Pereira, Rafael Fernandez-Martin, Dante A Paz and Daniel F Salamone
    Citation: Reproductive Biology and Endocrinology 2011 9:18
    Content type: Research Published on:
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