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  1. The role of ovarian reserve markers as predictors of the controlled ovarian stimulation (COS) response in intracytoplasmic sperm injection (ICSI) cycles in women with endometriosis has been much debated. The a...

    Authors: Safiya A Wahd, Shahla K Alalaf, Talha Al-Shawaf and Namir G Al-Tawil
    Citation: Reproductive Biology and Endocrinology 2014 12:120
  2. The impact of elevated estradiol on the day of human chorionic gonadotropin (hCG) administration on in vitro fertilization (IVF) outcomes has been debated for over 25 years. Some investigators have shown a pos...

    Authors: Michael T Zavy, LaTasha B Craig, Robert A Wild, Sana N Kahn, Dena O’Leary and Karl R Hansen
    Citation: Reproductive Biology and Endocrinology 2014 12:119
  3. Bovine granulosa cell culture models are important to understand molecular mechanisms of ovarian function. Folliculogenesis and luteinization are associated with increasing density of cells and local hypoxic c...

    Authors: Vijay S Baddela, Anja Baufeld, Vengala R Yenuganti, Jens Vanselow and Dheer Singh
    Citation: Reproductive Biology and Endocrinology 2014 12:118
  4. In vitro maturation (IVM) of immature oocytes retrieved from unstimulated ovaries may avoid side effects connected to hyperstimulation during IVF procedures, including the risk of cancer recurrence. In humans, th...

    Authors: Maria G Palmerini, Stefania A Nottola, Giovanni G Leoni, Sara Succu, Xhejni Borshi, Fiammetta Berlinguer, Salvatore Naitana, Yerbol Bekmukhambetov and Guido Macchiarelli
    Citation: Reproductive Biology and Endocrinology 2014 12:115
  5. The urge to have one’s own biological child supersedes any desire in life. Several options have been used to obtain gametes including pluripotent stem cells (embryonic ES and induced pluripotent iPS stem cells...

    Authors: Deepa Bhartiya, Indira Hinduja, Hiren Patel and Rashmi Bhilawadikar
    Citation: Reproductive Biology and Endocrinology 2014 12:114
  6. Many studies have proposed that putative ovarian stem cells (OSCs) derived from the ovarian surface epithelium (OSE) layer of adult mammalian ovaries can produce oocytes. Few studies have reported that ovaries...

    Authors: Bo Sun Joo, In Kook Jung, Min Jung Park, Jong Kil Joo, Ki Hyung Kim and Kyu-Sup Lee
    Citation: Reproductive Biology and Endocrinology 2014 12:113
  7. Assisted reproductive technology (ART) is a common treatment of choice for many couples facing infertility issues, be it due to male or female factor, or idiopathic. Employment of ART techniques, however, come...

    Authors: Ashok Agarwal, Damayanthi Durairajanayagam and Stefan S du Plessis
    Citation: Reproductive Biology and Endocrinology 2014 12:112
  8. Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte quality which is important for fertilization and development into viable offspring. Quality-compromised oocytes are ...

    Authors: Heide Schatten, Qing-Yuan Sun and Randall Prather
    Citation: Reproductive Biology and Endocrinology 2014 12:111
  9. Human mature oocytes are very susceptible to cryodamage. Several reports demonstrated that vitrification might preserve oocyte better than slow freezing. However, this is still controversial. Thus, larger clin...

    Authors: Veronica Bianchi, Guido Macchiarelli, Andrea Borini, Michela Lappi, Sandra Cecconi, Selenia Miglietta, Giuseppe Familiari and Stefania A Nottola
    Citation: Reproductive Biology and Endocrinology 2014 12:110
  10. The objective of this meta-analysis is to assess the impact of LH supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with gonadotropin releasing hormone (Gn...

    Authors: Yujing Xiong, Zhiqin Bu, Wei Dai, Meixiang Zhang, Xiao Bao and Yingpu Sun
    Citation: Reproductive Biology and Endocrinology 2014 12:109
  11. This review focuses on the possibility of improving the outcome of human IVF by studying the follicles where oocytes grow by ultrasound techniques. A comprehensive analysis of bi-dimensional (2D) and three-dim...

    Authors: Alberto Revelli, Giorgia Martiny, Luisa Delle Piane, Chiara Benedetto, Paolo Rinaudo and Ilan Tur-Kaspa
    Citation: Reproductive Biology and Endocrinology 2014 12:107
  12. Flow cytometric sorting can be used to separate sperm based on sex chromosome content. Differential fluorescence emitted by stained X- vs. Y-chromosome-bearing sperm enables sorting and collection of samples e...

    Authors: David S Karabinus, Donald P Marazzo, Harvey J Stern, Daniel A Potter, Chrispo I Opanga, Marisa L Cole, Lawrence A Johnson and Joseph D Schulman
    Citation: Reproductive Biology and Endocrinology 2014 12:106
  13. Embryos produced by in vitro fertilization (IVF) have a high level of aneuploidy, which is believed to be a major factor affecting the success of human assisted reproduction treatment. The aneuploidy rate of c...

    Authors: Judy FC Chow, William SB Yeung, Estella YL Lau, Vivian CY Lee, Ernest HY Ng and Pak-Chung Ho
    Citation: Reproductive Biology and Endocrinology 2014 12:105
  14. After spontaneous conception, the rate of miscarriage is more common in multiple rather than singleton pregnancies. However, the incidence of miscarriage is lower in in-vitro fertilization twin versus singleto...

    Authors: Erika Balassiano, Shaveta Malik, Praful Vaid, Eric S Knochenhauer and Michael L Traub
    Citation: Reproductive Biology and Endocrinology 2014 12:104
  15. The effect of paternal age on semen quality is controversial. In this retrospective study, the aim was to investigate the effects of advancing age on sperm parameters including reactive oxygen species (ROS), t...

    Authors: Saad Alshahrani, Ashok Agarwal, Mourad Assidi, Adel M Abuzenadah, Damayanthi Durairajanayagam, Ahmet Ayaz, Rakesh Sharma and Edmund Sabanegh
    Citation: Reproductive Biology and Endocrinology 2014 12:103
  16. Bisphenol A (BPA) is an applied chemical that is used in many industrial fields and is a potential endocrine disruption chemical (EDC) that is found in the environment. Bisphenol S (BPS) and polyethersulfone (...

    Authors: Jae Soon Kang, Jin-Soo Choi, Woo-Keun Kim, Yong-Ju Lee and June-Woo Park
    Citation: Reproductive Biology and Endocrinology 2014 12:102
  17. Glycosylation is one of the most common post-translational modifications of eukaryotic proteins and is known to undergo dynamic changes in a wide range of biological processes. To date, however, the glycan exp...

    Authors: Tomoko Hirakawa, Kaei Nasu, Kentaro Kai, Yoko Aoyagi, Terukazu Ishii, Tetsuya Uemura, Mitsutake Yano and Hisashi Narahara
    Citation: Reproductive Biology and Endocrinology 2014 12:100
  18. Evaluation of mitochondrial function offers an alternative to evaluate embryo development for assessment of oocyte viability, but little information is available on the relationship between mitochondrial and c...

    Authors: Nicola A Martino, Maria E Dell’Aquila, Manuel Filioli Uranio, Lucia Rutigliano, Michele Nicassio, Giovanni M Lacalandra and Katrin Hinrichs
    Citation: Reproductive Biology and Endocrinology 2014 12:99
  19. The use of insulin-sensitizing drugs has been shown to improve both the reproductive and the metabolic aspects of PCOS. However, the mechanisms by which metformin exerts its effects in PCOS are still not compl...

    Authors: Dorothea Kurzthaler, Dijana Hadziomerovic-Pekic, Ludwig Wildt and Beata E Seeber
    Citation: Reproductive Biology and Endocrinology 2014 12:98
  20. The use of complementary and alternative medicine and herbal products, especially traditional Chinese medicines, is progressively rising for both adults and children. This increased use is based on the popular...

    Authors: Dov Tiosano, Françoise Paris, Marina Grimaldi, Vera Georgescu, Nadège Servant, Zeev Hochberg, Patrick Balaguer and Charles Sultan
    Citation: Reproductive Biology and Endocrinology 2014 12:97
  21. The goal of this study was to assess the association between endometrial thickness on the chorionic gonadotropin (hCG) day and in vitro fertilization and embryo transfer (IVF-ET) outcome in normal responders a...

    Authors: Yu Wu, Xiaohong Gao, Xiang Lu, Ji Xi, Shan Jiang, Yin Sun and Xiaowei Xi
    Citation: Reproductive Biology and Endocrinology 2014 12:96
  22. Gonadotropins extracted from the urine of post-menopausal women have traditionally been used to stimulate folliculogenesis in the treatment of infertility and in assisted reproductive technology (ART). Product...

    Authors: Diego Ezcurra and Peter Humaidan
    Citation: Reproductive Biology and Endocrinology 2014 12:95
  23. Asthma is one of the most common conditions which complicate pregnancy. Pro- and anti-apoptotic mechanisms can be modulated by asthma accompanying pregnancy. Survivin, an anti-apoptotic protein has been implic...

    Authors: Andras Bikov, Renata Bocskei, Noemi Eszes, Aniko Bohacs, Gyorgy Losonczy, Janos Rigo, Ildiko Horvath and Lilla Tamasi
    Citation: Reproductive Biology and Endocrinology 2014 12:93
  24. Endometrial function is essential for embryo implantation. The aim of this study was to analyze gene expression profiles from individual endometrial samples obtained from women with repeated implantation failu...

    Authors: Alejandro Tapia-Pizarro, Paula Figueroa, Julio Brito, Juan Carlos Marín, David J Munroe and Horacio B Croxatto
    Citation: Reproductive Biology and Endocrinology 2014 12:92
  25. It is well established that spontaneous conceptus loss in swine is associated with an imbalance of both angiogenic and immunological factors. Leptin (LEP), a metabolic hormone, has also been implicated in the ...

    Authors: Ashley Kerr, Rami T Kridli, Kasra Khalaj, Jocelyn M Wessels, Ann Hahnel and Chandrakant Tayade
    Citation: Reproductive Biology and Endocrinology 2014 12:91
  26. Aromatase converts testosterone into 17beta-estradiol in granulosa cells, and the converted 17beta-estradiol contributes to follicular maturation. Additionally, excessive testosterone inhibits aromatase activi...

    Authors: Ching-Tien Lee, Jiz-Yuh Wang, Kuang-Yi Chou and Ming-I Hsu
    Citation: Reproductive Biology and Endocrinology 2014 12:90
  27. Polycystic ovary syndrome (PCOS) is a common endocrinopathy, associated with metabolic abnormalities. Metabolic features of various phenotypes of this syndrome are still debatable. The aim of present study hen...

    Authors: Fahimeh Ramezani Tehrani, Homeira Rashidi, Mahnaz Bahri Khomami, Maryam Tohidi and Fereidoun Azizi
    Citation: Reproductive Biology and Endocrinology 2014 12:89
  28. High plasma concentrations of the vitamin E-binding protein afamin have been previously shown to be associated with insulin resistance and metabolic syndrome. We set out to determine whether the concentration ...

    Authors: Beata Seeber, Elisabeth Morandell, Fabian Lunger, Ludwig Wildt and Hans Dieplinger
    Citation: Reproductive Biology and Endocrinology 2014 12:88
  29. The overall prevalence of infertility was estimated to be 3.5–16.7% in developing countries and 6.9–9.3% in developed countries. Furthermore, according to reports from some regions of sub-Saharan Africa, the p...

    Authors: Luis Bahamondes and Maria Y Makuch
    Citation: Reproductive Biology and Endocrinology 2014 12:87
  30. Polymorphisms at codons 307 and 680 are the most commonly encountered allelic variants of the follicle-stimulating hormone receptor (FSHR) gene. Studies in Caucasians suggest that certain FSHR variants are mor...

    Authors: Wanakan Singhasena, Tawiwan Pantasri, Waraporn Piromlertamorn, Sudarat Samchimchom and Teraporn Vutyavanich
    Citation: Reproductive Biology and Endocrinology 2014 12:86
  31. Oocyte fertilization and successful embryo implantation are key events marking the onset of pregnancy. In sexually reproducing organisms, embryogenesis begins with the fusion of two haploid gametes, each of wh...

    Authors: Allison Tscherner, Graham Gilchrist, Natasha Smith, Patrick Blondin, Daniel Gillis and Jonathan LaMarre
    Citation: Reproductive Biology and Endocrinology 2014 12:85
  32. Most human demographic data, particularly those on natural fertility populations, find no relationship or even a positive association between fertility and longevity. The present study aims to ascertain whethe...

    Authors: Juan J Tarín, Vanessa Gómez-Piquer, Silvia García-Palomares, Miguel A García-Pérez and Antonio Cano
    Citation: Reproductive Biology and Endocrinology 2014 12:84
  33. Synaptotagmin-1 (Syt1) is an abundant, evolutionarily conserved integral membrane protein that plays essential roles in neurotransmitter release and hormone secretion. Neurotransmitters secreted by hypothalami...

    Authors: Xinhong Luan, Lina Luo, Zhongzan Cao, Rongrong Li, Dawei Liu, Ming Gao, Mei Liu and Laiyou Wang
    Citation: Reproductive Biology and Endocrinology 2014 12:83
  34. Polycystic ovarian syndrome (PCOS) is characterized by increased ovarian angiogenesis and vascularity. Accumulating evidence indicates that vascular endothelial growth factor (VEGF) is increased in PCOS and ma...

    Authors: Reshef Tal, David B Seifer, Richard V Grazi and Henry E Malter
    Citation: Reproductive Biology and Endocrinology 2014 12:82
  35. Oocyte secreted factors (OSFs), including growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), play an important role in the process of follicular development and oocyte maturation...

    Authors: Yi Li, Rui-Qi Li, Song-Bang Ou, Ning-Feng Zhang, Ling Ren, Li-Na Wei, Qing-Xue Zhang and Dong-Zi Yang
    Citation: Reproductive Biology and Endocrinology 2014 12:81
  36. Fetal adaptations to high fat (HF) diet in utero (IU) that may predispose to Metabolic Syndrome (MetS) in adulthood include changes in fetal hepatic gene expression. Studies were performed to determine whether...

    Authors: Maria del Mar Plata, Lyda Williams, Yoshinori Seki, Kirsten Hartil, Harpreet Kaur, Chia-Lei Lin, Ariana Fiallo, Alan S Glenn, Ellen B Katz, Mamta Fuloria, Maureen J Charron and Patricia M Vuguin
    Citation: Reproductive Biology and Endocrinology 2014 12:80
  37. Estrogen receptors play an important role in mediating estrogen action on target tissues, and the estrogen is relevant to male infertility. Single nucleotide polymorphisms (SNPs) in estrogen receptors may be a...

    Authors: Tian-Fu Li, Qiu-Yue Wu, Cui Zhang, Wei-Wei Li, Na Li, Ying-Xia Cui, Xiao-Jun Li and Xin-Yi Xia
    Citation: Reproductive Biology and Endocrinology 2014 12:79
  38. Preantral follicles are the majority of the ovarian follicle population and their use as a source of homogeneous oocytes for bovine reproductive biotechnologies could result in a substantial advance in this fi...

    Authors: Valdevane R Araújo, Melba O Gastal, José R Figueiredo and Eduardo L Gastal
    Citation: Reproductive Biology and Endocrinology 2014 12:78
  39. Cadmium (Cd) is a major environmental pollutant that causes multiple adverse health effects in humans and animals. In this study, we investigated Cd-mediated toxic effects in rats during pregnancy and endocrin...

    Authors: Fan Wang, Qiong Zhang, Xiaojie Zhang, Shunqun Luo, Duyun Ye, Yi Guo, Sisi Chen and Yinping Huang
    Citation: Reproductive Biology and Endocrinology 2014 12:77
  40. The majority of beta-defensin family members are exclusively expressed in the epididymis, and some members have been shown to play essential roles in sperm maturation and fertility in rats, mice and humans. Th...

    Authors: Shuang-Gang Hu, Mei Zou, Guang-Xin Yao, Wu-Bin Ma, Qin-Ling Zhu, Xiang-Qi Li, Zi-Jiang Chen and Yun Sun
    Citation: Reproductive Biology and Endocrinology 2014 12:76
  41. Overweight and obese women have been shown to have an increased risk of recurrent miscarriage as well as other adverse reproductive outcomes, but it is yet unclear whether this is due to an effect on the endom...

    Authors: Mostafa Metwally, Rebecca Preece, Jerry Thomas, William Ledger and Tin Chiu Li
    Citation: Reproductive Biology and Endocrinology 2014 12:75
  42. Several types of T cells have been associated with the pathogenesis of unexplained recurrent spontaneous abortion (URSA), including Th1/Th2/Th17/Tregs cell. It has been appreciated that immunotherapy with pate...

    Authors: Li Wu, Li-Hua Luo, Ying-Xin Zhang, Qing Li, Bo Xu, Gui-Xiang Zhou, Hong-Bing Luan and Yu-Sheng Liu
    Citation: Reproductive Biology and Endocrinology 2014 12:74
  43. Maternal overnutrition during pregnancy is associated with an increased risk of obesity and cardiometabolic disease in the offspring; a phenomenon attributed to ‘developmental programming’. The post-weaning de...

    Authors: Vicky King, Jane E Norman, Jonathan R Seckl and Amanda J Drake
    Citation: Reproductive Biology and Endocrinology 2014 12:73
  44. Feed intake affects the GH-IGF system and may be a key factor in determining the ovarian follicular growth rate. In fat mares, the plasma IGF-1 concentration is high with low GH and a quick follicular growth r...

    Authors: Juan Salazar-Ortiz, Philippe Monget and Daniel Guillaume
    Citation: Reproductive Biology and Endocrinology 2014 12:72
  45. Sperm chromatin structure is often impaired; mainly due to oxidative damage. Antioxidant treatments do not consistently produce fertility improvements and, when given at high doses, they might block essential ...

    Authors: Maurizio Dattilo, Dominique Cornet, Edouard Amar, Marc Cohen and Yves Menezo
    Citation: Reproductive Biology and Endocrinology 2014 12:71
  46. Histidine-rich Glycoprotein (HRG) has previously been shown to have an impact on implantation and fertility. The aim of this study was to investigate if there is an association between the HRG A1042G single nu...

    Authors: Evangelia Elenis, Karin E Lindgren, Helena Karypidis, Alkistis Skalkidou, Frida Hosseini, Katarina Bremme, Britt-Marie Landgren, Lottie Skjöldebrand-Sparre, Anneli Stavreus-Evers, Inger Sundström-Poromaa and Helena Åkerud
    Citation: Reproductive Biology and Endocrinology 2014 12:70

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