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Table 2 PCOS studies with nitric oxide and oxidative stress

From: A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS

Topic with PCOS

Study Title

Reference

Nitric oxide

Nitric oxide (NO) levels in patients with polycystic ovary syndrome (PCOS): a meta-analysis

Meng C [134].

 

Clomiphene citrate increases nitric oxide, interleukin-10 and reduces matrix metalloproteinase-9 in women with polycystic ovary syndrome

Sylus AM et al., [172]

 

Impaired Arginine Metabolism Coupled to a Defective Redox Conduit Contributes to Low Plasma Nitric Oxide in Polycystic Ovary Syndrome

Krishna MB et al., [51]

 

Nitric oxide donors improve the ovulation and pregnancy rates in anovulatory women with polycystic ovary syndrome treated with clomiphene citrate: A RCT

Mahran A et al., [112]

 

Cardiac Nitric Oxide Synthases and Na+/K+-ATPase in the Rat Model of Polycystic Ovary Syndrome Induced by Dihydrotestosterone

Tepavčević S et al., [173]

 

Detailed characterisation of circulatory nitric oxide and free radical indices–is there evidence for abnormal cardiovascular homeostasis in young women with polycystic ovary syndrome?

Willis GR et al., [174]

 

Assessment of paraoxonase 1, xanthine oxidase and glutathione peroxidase activities, nitric oxide and thiol levels in women with polycystic ovary syndrome

Baskol G et al., [158]

 

Polymorphisms of the endothelial nitric oxide synthase gene in premenopausal women with polycystic ovary syndrome

Walch K et al., [175]

 

Nitric oxide and fibrinogen in polycystic ovary syndrome: associations with insulin resistance and obesity

Nácul AP et al., [176]

Oxidative stress

The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review

Batóg G et al., [177]

 

Heavy Metals and Essential Elements in Association with Oxidative Stress in Women with Polycystic Ovary Syndrome-A Systematic Review

Srnovršnik T et al., [178]

 

Efficacy of omega-3 polyunsaturated fatty acids on hormones, oxidative stress, and inflammatory parameters among polycystic ovary syndrome: a systematic review and meta-analysis

Yuan J et al., [179]

 

Influence of n-3 fatty acid supplementation on inflammatory and oxidative stress markers in patients with polycystic ovary syndrome: a systematic review and meta-analysis

Tosatti JA et al., [180]

 

Oxidative Stress and Polycystic Ovary Syndrome: A Brief Review.

Mohammadi M [12]

 

The Effects of Probiotic Supplementation on Clinical Symptom, Weight Loss, Glycemic Control, Lipid and Hormonal Profiles, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials

Tabrizi R et al., [181]

 

The Effects of Vitamin D Supplementation on Biomarkers of Inflammation and Oxidative Stress Among Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Akbari M et al., [182]

 

Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis

Murri M et al., [183]

 

Polycystic Ovary Syndrome and Oxidative Stress-From Bench to Bedside.

Zeber-Lubecka; et al., [17]

 

The Silent Threat to Women’s Fertility: Uncovering the Devastating Effects of Oxidative Stress

Kaltsas A et al., [184]

 

A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS)

Siddiqui S et al., [28]

 

Reactive oxygen species in reproduction: harmful, essential or both?

Jamil M et al., [185]

 

Mitochondrial function in women with polycystic ovary syndrome

Cozzolino M & Seli E [186]

 

Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress

Jiang Y et al., [187]

 

Oxidative stress in oocyte aging and female reproduction

Wang L et al., [188]

 

Controlling chronic low-grade inflammation to improve follicle development and survival

Yang Z et al., [189]

 

A novel and compact review on the role of oxidative stress in female reproduction

Lu J et al., [190]

 

Source and amount of carbohydrate in the diet and inflammation in women with polycystic ovary syndrome

Barrea L et al., [191]

 

Impact of stress on female reproductive health disorders: Possible beneficial effects of shatavari (Asparagus racemosus)

Pandey AK et al., [192]

 

Oxidative Stress in Granulosa-Lutein Cells From In Vitro Fertilization Patients

Ávila J et al., [193]

 

Oxidative stress and cardiovascular complications in polycystic ovarian syndrome

Hyderali BN & Mala K [115]

 

The effects of oxidative stress on female reproduction: a review.

Agarwal A et al., [194]