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Table 3 Association of the three MTHFR/MTRR mutations and homocysteine levels

From: Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women

 

Genotype

βa (95% CI)

P value

MTHFR C677T

CC

reference

 

CT

0.034 (-0.124–0.193)

0.672

TT

0.025 (-0.141–0.192)

0.764

MTHFR A1298C

AA

reference

 

AC

0.867 (0.577–1.158)

< 0.001

CC

2.092 (1.574–2.611)

< 0.001

MTRR A66G

AA

reference

 

AG

-0.189 (-0.499–0.122)

0.233

GG

0.704 (0.189–1.219)

0.007

  1. a Adjusted for potential confounders, including age, body mass index, folate, history of smoking, drinking, and hypertensive family history
  2. Bold values indicate significance (P < 0.05)