In rats with estradiol valerate-induced polycystic ovary syndrome, the acute blockade of ovarian β-adrenoreceptors improve ovulation

Table 1 Ovulatory response in rats with EV and blocking β-adrenergic receptors in ovaries at 60-day old

Groups	N	Ovulation rate	Ova shed
Vh	10	10/10	12.3 ± 0.7
Vh + Pro	10	10/10	8.4 ± 1.0^a
EV	8	1/8^a,b	13
EV + Pro	9	6/9^a,b,c	4.0 ± 1.67^a

Ovulation rate and number ova shed in animals treated with vehicle (Vh) or estradiol valerate (EV) at 10 day old and injected with propranolol (Pro) [10⁻⁴ M] [20 μL] into the both ovarian bursas at 60 day of age. The animals were sacrificed at next estrus day. Ovulation rate, ^ap < 0.05 vs Vh group, ^bp < 0.05 Vh + Pro or ^cp < 0.05 vs EV group (Fisher’s test); number ova shed ^ap < 0.05 vs Vh group (Kruskal-Wallis test)

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