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Correction to: Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages

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The original article was published in Reproductive Biology and Endocrinology 2018 16:42

Correction to: Reprod Biol Endocrinol (2018) 16:42

https://doi.org/10.1186/s12958-018-0360-z

The authors regret that the incorrect identification of “omega-3 arachidonic acid” published in the original manuscript [1]. This classification is incorrect as arachidonic acid is an omega-6 polyunsaturated fatty acid. From a mechanistic standpoint, this mistake might have significance, as arachidonic acid is hypothesized to play a role in inflammatory processes. We have carefully double-checked our original data and compared the fragmentation spectra and m/z referring to Metlin Database again. We are sure that the metabolite should be arachidonic acid, instead of omega-3 arachidonic acid. Given that this misclassification is made in several places within the article’s abstract and text, a correction is warranted.

Accordingly, the name “omega-3 arachidonic acid” mentioned in the following parts should be corrected as “arachidonic acid”:

  • In the results section of Abstract: “The eutopic endometrium metabolomic profile of the endometriosis patients was characterized by a significant increase in the concentration of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”.

  • In the last paragraph of Introduction: “The eutopic endometrium metabolomic profile of endometriosis patients was characterized by a significant increase in the concentration of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”.

  • In the first paragraph of the section with the subheading “Identification of detected metabolites” of Results: “Obviously, levels of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine…..”

  • In the first paragraph of Discussion: “In this regard, 11 metabolites including hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”

  • Figure 2D, “Omega-3 Arachidonic acid”

  • In the third row of Figure 3, “omega-3 arachidonic acid”

  • In the third graph in the first row of Figure 4, “Omega-3 Arachidonic acid”

  • In the 4th row of RPLC mode in Table 2, “Omega-3 Arachidonic acid”

The authors would like to apologize for any inconvenience caused.

Reference

  1. 1.

    Li J, et al. Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages. Reprod Biol Endocrinol. 2018;16:42. https://doi.org/10.1186/s12958-018-0360-z.

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Author information

Correspondence to Huichang Bi.

Additional information

The original article can be found online at https://doi.org/10.1186/s12958-018-0360-z

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Li, J., Guan, L., Zhang, H. et al. Correction to: Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages. Reprod Biol Endocrinol 17, 89 (2019) doi:10.1186/s12958-019-0532-5

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