Irvine DS, Macleod IC, Templeton AA, Masterton A, Taylor A. A prospective clinical study of the relationship between the computer-assisted assessment of human semen quality and the achievement of pregnancy in vivo. Hum Reprod. 1994;9(12):2324–34.
CAS
PubMed
Google Scholar
Shen HM, Dai J, Chia SE, Lim A, Ong CN. Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality. Hum Reprod. 2002;17(5):1266–73.
Article
PubMed
Google Scholar
Barroso G, Morshedi M, Oehninger S. Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa. Hum Reprod. 2000;15(6):1338–44.
Article
CAS
PubMed
Google Scholar
Gandini L, Lombardo F, Paoli D, Caponecchia L, Familiari G, Verlengia C, et al. Study of apoptotic DNA fragmentation in human spermatozoa. Hum Reprod. 2000;15(4):830–9.
Article
CAS
PubMed
Google Scholar
Brahem S, Jellad S, Ibala S, Saad A, Mehdi M. DNA fragmentation status in patients with necrozoospermia. Syst Biol Reprod Med. 2012;58(6):319–23. doi:10.3109/19396368.2012.710869.
Article
CAS
PubMed
Google Scholar
Evenson DP, Jost LK, Marshall D, Zinaman MJ, Clegg E, Purvis K, et al. Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod. 1999;14(4):1039–49.
Article
CAS
PubMed
Google Scholar
Bungum M, Humaidan P, Spano M, Jepson K, Bungum L, Giwercman A. The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod. 2004;19(6):1401–8. doi:10.1093/humrep/deh280.
Article
CAS
PubMed
Google Scholar
Spano M, Bonde JP, Hjollund HI, Kolstad HA, Cordelli E, Leter G. Sperm chromatin damage impairs human fertility. The Danish First Pregnancy Planner Study Team. Fertil Steril. 2000;73(1):43–50.
Article
CAS
PubMed
Google Scholar
Henkel R, Hajimohammad M, Stalf T, Hoogendijk C, Mehnert C, Menkveld R, et al. Influence of deoxyribonucleic acid damage on fertilization and pregnancy. Fertil Steril. 2004;81(4):965–72. doi:10.1016/j.fertnstert.2003.09.044.
Article
CAS
PubMed
Google Scholar
Evenson DP, Wixon R. Clinical aspects of sperm DNA fragmentation detection and male infertility. Theriogenology. 2006;65(5):979–91. doi:10.1016/j.theriogenology.2005.09.011.
Article
CAS
PubMed
Google Scholar
Wilton LJ, Temple-Smith PD, Baker HW, de Kretser DM. Human male infertility caused by degeneration and death of sperm in the epididymis. Fertil Steril. 1988;49(6):1052–8.
CAS
PubMed
Google Scholar
Mallidis C, Lim TC, Hill ST, Skinner DJ, Brown DJ, Johnston WI, et al. Necrospermia and chronic spinal cord injury. Fertil Steril. 2000;74(2):221–7.
Article
CAS
PubMed
Google Scholar
Nduwayo L, Barthelemy C, Lansac J, Tharanne MJ, Lecomte P. Management of necrospermia. Contracept Fertil Sex. 1995;23(11):682–5.
CAS
PubMed
Google Scholar
Lerda D, Rizzi R. Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D). Mutat Res. 1991;262(1):47–50.
Article
CAS
PubMed
Google Scholar
Health OCfWs. Sperm Chromatin Structure Assay. http://www.ohsu.edu/xd/health/services/women/services/fertility/fertility-services/lab-services/sperm-chromatin-structure.cfm. Accessed April 5, 2014.
Moskovtsev SI, Librach CL. Methods of sperm vitality assessment. Methods Mol Biol. 2013;927:13–9. doi:10.1007/978-1-62703-038-0_2.
Article
CAS
PubMed
Google Scholar
Zini A, Kamal K, Phang D, Willis J, Jarvi K. Biologic variability of sperm DNA denaturation in infertile men. Urology. 2001;58(2):258–61.
Article
CAS
PubMed
Google Scholar
WHO laboratory manual for the examination and processing of human semen. 2010. http://www.who.int/reproductivehealth/publications/infertility/9789241547789/en/. Accessed March 30, 2014 2014.
Gosalvez J, Cortes-Gutierrez EI, Nunez R, Fernandez JL, Caballero P, Lopez-Fernandez C, et al. A dynamic assessment of sperm DNA fragmentation versus sperm viability in proven fertile human donors. Fertil Steril. 2009;92(6):1915–9. doi:10.1016/j.fertnstert.2008.08.136.
Article
CAS
PubMed
Google Scholar
Arends MJ, Morris RG, Wyllie AH. Apoptosis. The role of the endonuclease. Am J Pathol. 1990;136(3):593–608.
PubMed Central
CAS
PubMed
Google Scholar
Jaattela M. Programmed cell death: many ways for cells to die decently. Ann Med. 2002;34(6):480–8.
Article
PubMed
Google Scholar
Gosalvez J, Cortes-Gutierez E, Lopez-Fernandez C, Fernandez JL, Caballero P, Nunez R. Sperm deoxyribonucleic acid fragmentation dynamics in fertile donors. Fertil Steril. 2009;92(1):170–3. doi:10.1016/j.fertnstert.2008.05.068.
Article
CAS
PubMed
Google Scholar
Cortes-Gutierrez EI, Crespo F, Gosalvez A, Davila-Rodriguez MI, Lopez-Fernandez C, Gosalvez J. DNA fragmentation in frozen sperm of Equus asinus: Zamorano-Leones, a breed at risk of extinction. Theriogenology. 2008;69(8):1022–32. doi:10.1016/j.theriogenology.2008.02.002.
Article
CAS
PubMed
Google Scholar
Lopez-Fernandez C, Crespo F, Arroyo F, Fernandez JL, Arana P, Johnston SD, et al. Dynamics of sperm DNA fragmentation in domestic animals II. The stallion. Theriogenol. 2007;68(9):1240–50. doi:10.1016/j.theriogenology.2007.08.029.
Article
CAS
Google Scholar
Irvine DS, Twigg JP, Gordon EL, Fulton N, Milne PA, Aitken RJ. DNA integrity in human spermatozoa: relationships with semen quality. J Androl. 2000;21(1):33–44.
CAS
PubMed
Google Scholar
Sun JG, Jurisicova A, Casper RF. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod. 1997;56(3):602–7.
Article
CAS
PubMed
Google Scholar
Lopes S, Sun JG, Jurisicova A, Meriano J, Casper RF. Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection. Fertil Steril. 1998;69(3):528–32.
Article
CAS
PubMed
Google Scholar
Muratori M, Maggi M, Spinelli S, Filimberti E, Forti G, Baldi E. Spontaneous DNA fragmentation in swim-up selected human spermatozoa during long term incubation. J Androl. 2003;24(2):253–62.
CAS
PubMed
Google Scholar
Morris ID, Ilott S, Dixon L, Brison DR. The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development. Hum Reprod. 2002;17(4):990–8.
Article
CAS
PubMed
Google Scholar
Brahem S, Mehdi M, Elghezal H, Saad A. Semen processing by density gradient centrifugation is useful in selecting sperm with higher double-strand DNA integrity. Andrologia. 2011;43(3):196–202. doi:10.1111/j.1439-0272.2010.01050.x.
Article
CAS
PubMed
Google Scholar
Zini A, Sigman M. Are tests of sperm DNA damage clinically useful? Pros and cons. J Androl. 2009;30(3):219–29.
Article
CAS
PubMed
Google Scholar
Virro MR, Larson-Cook KL, Evenson DP. Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles. Fertil Steril. 2004;81(5):1289–95. doi:10.1016/j.fertnstert.2003.09.063.
Article
PubMed
Google Scholar
Dar S, Grover SA, Moskovtsev SI, Swanson S, Baratz A, Librach CL. In vitro fertilization-intracytoplasmic sperm injection outcome in patients with a markedly high DNA fragmentation index (>50%). Fertil Steril. 2013;100(1):75–80. doi:10.1016/j.fertnstert.2013.03.011.
Article
PubMed
Google Scholar
Cohen-Bacrie P, Belloc S, Menezo YJ, Clement P, Hamidi J, Benkhalifa M. Correlation between DNA damage and sperm parameters: a prospective study of 1,633 patients. Fertil Steril. 2009;91(5):1801–5. doi:10.1016/j.fertnstert.2008.01.086.
Article
PubMed
Google Scholar
Zini A, Boman JM, Belzile E, Ciampi A. Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis. Hum Reprod. 2008;23(12):2663–8.
Article
CAS
PubMed
Google Scholar
Fang S, Baker HW. Male infertility and adult polycystic kidney disease are associated with necrospermia. Fertil Steril. 2003;79(3):643–4.
Article
PubMed
Google Scholar
Correa-Perez JR, Fernandez-Pelegrina R, Aslanis P, Zavos PM. Clinical management of men producing ejaculates characterized by high levels of dead sperm and altered seminal plasma factors consistent with epididymal necrospermia. Fertil Steril. 2004;81(4):1148–50. doi:10.1016/j.fertnstert.2003.09.047.
Article
PubMed
Google Scholar