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Table 2 The percentage expression of various co-stimulatory molecules on the surface of mDCs and pDCs subsets in cervical mucosa.

From: Role of cervical dendritic cell subsets, co-stimulatory molecules, cytokine secretion profile and beta-estradiol in development of sequalae to Chlamydia trachomatis infection

 

% expression on mDCs

% expression on pDCs

 

CT+ Fertile

(n = 34)

CT+ with FD

(n = 20)

Controls

(n = 28)

CT+ Fertile

(n = 34)

CT+ with FD

(n = 20)

Controls

(n = 28)

CD80

16.0 ± 3.0a

12.0 ± 2.2

7.0 ± 0.06

8.0 ± 0.7

32.5 ± 2.5b

6.0 ± 0.5

CD83

23.0 ± 0.6a

28.0 ± 1.8a

11.0 ± 2.0

18.0 ± 2.0a

38.0 ± 2.4b

8.0 ± 0.7

CD86

62.0 ± 7.0

59.0 ± 2.6

82.0 ± 5.0

21.0 ± 4.0

20.0 ± 1.9

31.0 ± 2.0

CD1a

43.0 ± 3.0a

37.0 ± 3.8a

18.0 ± 3.0

45.0 ± 3.0

41.0 ± 2.7

28.0 ± 1.0

  1. Note: CT-Chlamydia trachomatis; FD-Fertility Disorders. The data are means ± SD. To study expression of various costimulatory molecules on mDC and pDC subsets, the gate was set on LIN-DR+ cells, and LIN-DR+ cells are again evaluated on quadrants having one axis as FL-2 (having Abs for costimulatory markers); aP < 0.01 compared to controls; bP < 0.01 compared to controls and CT positive fertile women.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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