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Table 1 Characteristics of the patients in the two groups

From: Reproductive outcomes of dual trigger therapy with GnRH agonist and hCG versus hCG trigger in women with diminished ovarian reserve: a retrospective study

 

hCG trigger

Dual trigger

p value

N

 

N  = 337

N  = 397

  

The baseline characteristics

 Age (year)

37. 4 ± 5.11

37.4 ± 5.07

0.963a

734

 BMI (kg/m2)

23.1 ± 3.37

22.5 ± 3.31

0.014a

733

 FSH (IU/L)

11.8 ± 6.08

10.2 ± 5.25

 < 0.001a

711

 E2 (pmol/L)

189 ± 119

179 ± 98.7

0.192a

712

 P (nmol/L)

1.04 (0.69, 1.49)

1.05 (0.75, 1.42)

0.989b

682

 PRL (ng/ml)

12.6 ± 7.78

12.6 ± 6.94

0.922a

623

 LH (IU/L)

3.80 (2.58, 5.58)

3.40 (2.35, 5.05)

0.016b

712

 T (nmol/l)

0.69 (0.69, 0.69)

0.69 (0.69,0.69)

0.915b

587

 A (nmol/L)

4.39 (3.03, 6.38)

4.66 (3.50, 6.64)

0.160b

515

 AMH (ng/mL)

0.41 (0.18, 0.69)

0.52 (0.28, 0.96)

 < 0.001b

717

Dosage of Gn (IU)

1739 ± 912

2075 ± 1001

 < 0.001a

734

Duration of stimulation (d)

11.9 ± 2.66

11.5 ± 2.13

0.058a

725

Hormone levels on trigger day

 LH (IU/L)

4.05 (2.11, 7.44)

3.07 (1.87, 6.06)

 < 0.001b

727

 E2 (pmol/L)

1586 (946.00, 2516.75)

1744 (1077.25, 3099.25)

0.005b

728

 P (nmol/L)

1.47 (1.05, 2.09)

1.54 (1.01, 2.39)

0.202b

727

Previous stimulation cycles and cancellations

1.4 ± 1.18

1.20 ± 1.28

0.071a

734

Mild stimulation

  

0.006c

734

 LE

195 (57.9%)

274 (69.0%)

  

 CC

67 (19.9%)

54 (13.6%)

  

 LE + CC

75 (22.3%)

69 (17.4%)

  
  1. BMI Body mass index, FSH Follicle-stimulating hormone, PRL Prolactin, LH Luteinizing hormone, AMH Anti-Müllerian hormone, LE Letrozole, CC Clomiphene
  2. Data are presented as the mean ± SD or median (IQR) 
  3. aIndependent Student’s t test
  4. bMann‒Whitney U test 
  5. cPearson’s chi-squared test