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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression

Fig. 5

Nrf2 may be a key driver for EnSCs to inhibit ferroptosis and repair damage. A Combinatorial analysis of the related genes about POF, cisplatin, ferroptosis and EnSCs uncovered 20 common genes, among which was Nrf2. B-C Nrf2 protein expression levels were detected by Western blotting. D Nrf2 mRNA expression levels were detected by qRT-PCR. E Nrf2 protein expression levels in ovarian tissue were detected by immunohistochemistry. Scale bars in the IHC staining represent 100 μm. The results were expressed as mean ± SEM (****P < 0.0001, * versus control group; ####P < 0.0001, # versus cis (10 µM cisplatin) group)

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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