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Table 1 Maternal outcomes of all documented pregnancies, N = 47. Data presented as absolute numbers (N) and percentages (%)

From: Pregnancy and acromegaly: clinical outcomes of retrospectively analysed data from the German acromegaly registry

 

N

%

Invasive treatment before pregnancy

Surgical treatment

  Pregnant women (N = 31)

27

87.1

   -one pregnancy (N = 16)

15

93.6

   -two pregnancies (N = 14)

11

78.6

   -three pregnancies (N = 1)

1

100.0

Conventional radiotherapy

  Pregnant women (N = 31)

3

9.7

   -one pregnancy (N = 16)

2

12.5

   -two pregnancies (N = 14)

1

7.1

Medication before pregnancy

  Dopamine agonists

15

31.9

  Somatostatin analog

29

61.7

  GH-receptor antagonist

2

4.3

Pituitary insufficiency before pregnancy

3

6.4

Pregnancy progress

  Gestational diabetes

5

10.6

  Gestational hypertension/ preeclampsia

3

6.4

Disease activity

  Increase

3

6.4

  Decrease

2

4.3

  Unchanged

17

36.2

  Missing information

25

53.2

Tumor size

  Increase

4

8.5

  Decrease

0

0.0

  Unchanged

15

31.9

  Missing information

28

59.6

Delivery

Birth procedure

  Spontaneous delivery

16

34.0

  Caesarean section

16

34.0

  Missing information

15

31.9

Birth complications

  None

41

87.2

  Misscarriages

3

6.4

  Shoulder dystocia

0

0.0

  Others

3

6.4