Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway

Table 2 Body weight and insulin resistance of the mice in each group

	Normal + saline	Obesity + saline	Normal + liraglutide	Obesity + liraglutide
Body weight(g)	28.10 ± 1.08	34.78 ± 1.88^###	27.23 ± 0.99	29.69 ± 0.77***^###
FBG (mmol/L)	6.07 ± 0.97	11.45 ± 1.04^##	5.54 ± 0.70	9.28 ± 0.99***^###
INS (mIU/L)	7.05 ± 0.55	8.78 ± 1.13^##	6.18 ± 0.54	5.05 ± 0.67***^###
HOMA-IR	1.91 ± 0.37	4.64 ± 0.55^###	1.60 ± 0.16	2.13 ± 0.33***

Values are the mean ± SD (n = 6 per group). The means of multiple samples of mouse body weight and insulin (INS) data were compared using one-way ANOVA, and two-group comparisons were made using the LSD method. Mouse fasting blood glucose (FBG) and the homeostasis model assessment of insulin resistance (HOMA-IR) were compared using the Welch test for mean comparisons between samples of multiple groups and Tamhane’s T2 method for two-group comparisons. Between saline and liraglutide, ***p < 0.001; between normal and obese, ^##p < 0.01, ^###p < 0.001

ISSN: 1477-7827