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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway

Fig. 3

Glucagon-like peptide-1 receptor (GLP-1R) and adenylate cyclase-3 (AC3) expression at the mRNA levels and protein levels, and cyclic adenosine monophosphate (cAMP) levels and Protein kinase A (PKA) activity in testicular tissues of mice in each group. Notes: Values are the mean ± SD (n = 3 per group, repeat 3 times). The means of multiple samples of mouse testis tissue GLP-1R mRNA expression data and GLP-1R, AC3 protein expression data, as well as cAMP levels and PKA activity were compared using one-way ANOVA, and two-group comparisons were made using the LSD method. Mouse testis tissue AC3 mRNA data were compared using the Welch test for mean comparisons between samples of multiple groups and Tamhane’s T2 method for two-group comparisons. Between saline and liraglutide, *p < 0.05, ***p < 0.001; between normal and obese, #p < 0.05, ##p < 0.01, ###p < 0.001

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