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Table 4 Clinical pregnancy and neonatal outcomes between patients who underwent single good-quality blastocyst transfer and those who underwent transfer of a second poor-quality blastocyst with a good-quality blastocyst before and after PS matching

From: Effect of frozen-thawed embryo transfer with a poor-quality embryo and a good-quality embryo on pregnancy and neonatal outcomes

Variable

Blastocyst transfer

Before matching

After matching

SET- GQE (N = 523)

DET- GQE + PQE (N = 316)

P value

SET- GQE (N = 283)

DET- GQE + PQE (N = 283)

P value

Implantation n (%)

274 (52.4)

227 (35.9)

0.000

137 (48.4)

207 (36.6)

0.001

OR (95%CI)

Reference

0.584 (0.454—0.752)

0.000

Reference

0.656 (0.485—0.886)

0.006

Clinical Pregnancy n (%)

269 (51.4)

180 (57.0)

0.120

134 (47.3)

163 (57.6)

0.015

OR (95%CI)

Reference

1.607 (1.180—2.188)

0.003

Reference

1.579 (1.123—2.221)

0.009

Live birth n (%)

213 (40.7)

140 (44.3)

0.309

104 (36.7)

126 (44.5)

0.060

OR (95%CI)

Reference

1.512 (1.109—2.060)

0.009

Reference

1.477 (1.046—2.086)

0.027

Multiple birth n (%)

2 (0.9)

27 (19.3)

0.000

1 (1.0)

26 (20.6)

0.000

OR (95%CI)

Reference

31.410 (6.749—146.186)

0.000

Reference

28.355 (3.926—204.790)

0.001

Miscarriage n (%)

56 (20.8)

40 (22.2)

0.722

30 (22.4)

37 (22.7)

0.949

OR (95%CI)

Reference

0.928 (0.570—1.513)

0.766

Reference

0.991 (0.573- 1.713)

0.974

Preterm birth n (%)

12 (5.6)

19 (13.6)

0.010

5(4.8)

18 (14.3)

0.017

OR (95%CI)

Reference

2.822 (1.247—6.384)

0.013

Reference

3.299 (1.195—9.106)

0.021

Gestational age (weeks)

39.0 ± 1.9

38.1 ± 2.4

0.000

38.9 ± 1.6

38.0 ± 2.5

0.000

OR (95%CI)

Reference

0.578 (0.364—0.916)

0.020

Reference

0.572 (0.345—0.948)

0.030

Birth height (mm)

49.7 ± 3.8

48.7 ± 3.6

0.006

49.5 ± 5.2

48.9 ± 3.2

0.233

OR (95%CI)

Reference

0.464 (0.251—0.858)

0.014

Reference

0.548 (0.282—1.068)

0.077

Birth weight (g)

3341.0 ± 517.2

3063.7 ± 615.8

0.000

3337.5 ± 561.9

3066.6 ± 617.8

0.000

OR (95%CI)

Reference

0.940 (0.907—0.975)

0.001

Reference

0.943 (0.903—0.984)

0.007

Low birth weight n (%)

13 (6.0)

23 (13.8)

0.010

8 (7.6)

21 (13.8)

0.123

OR (95%CI)

Reference

1.538 (0.601—3.933)

0.369

Reference

1.386 (0.526—3.656)

0.509

Congenital anomalies n (%)

0 (0)

1 (0.6)

0.437

0 (0)

1 (0.7)

1.000

OR (95%CI)

-

-

-

-

-

-

  1. Values are expressed as n (%), percentage (%) or mean ± standard deviation (SD) unless otherwise stated. P-values in bold depict statistical significance (P < 0.05) in comparison between SET-GQE and DET-GQE + PQE. ORs were adjusted for variables presented in the part of statistical analysis using multivariate GEE model before matching. ORs after matching were adjusted for propensity score
  2. SET Single embryo transfer, DET Double embryo transfer, GQE Good quality embryo, PQE Poor quality embryo, OR Odds ratio
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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