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Table 2 Baseline characteristics between single good-quality blastocyst transfer and transfer of a second poor-quality blastocyst with a good-quality blastocyst before and after PS matching

From: Effect of frozen-thawed embryo transfer with a poor-quality embryo and a good-quality embryo on pregnancy and neonatal outcomes

Variable

Before matching

After matching

SET- GQE (N = 523)

DET- GQE + PQE (N = 316)

P value

SET- GQE (N = 283)

DET- GQE + PQE (N = 283)

P value

Maternal age (y)

32.4 ± 4.2

33.4 ± 4.4

0.001

33.2 ± 4.3

33.1 ± 4.3

0.937

Paternal age (y)

34.1 ± 5.2

35.1 ± 5.5

0.008

34.9 ± 5.2

34.9 ± 5.5

0.994

BMI (kg/m2)

22.3 ± 3.3

22.8 ± 3.3

0.056

22.5 ± 3.3

22.7 ± 3.3

0.498

Duration of infertility (y)

3.0 ± 2.3

3.2 ± 2.3

0.285

3.1 ± 2.4

3.1 ± 2.3

0.990

Type of infertility n (%)

 Primary

343 (65.6)

202 (63.9)

0.626

173 (61.1)

185 (65.4)

0.295

 Secondary

180 (34.4)

114 (36.1)

110 (38.9)

98 (34.6)

 Basal FSH (IU/L)

8.5 ± 4.8

9.2 ± 5.4

0.076

8.8 ± 5.6

9.2 ± 5.5

0.461

 AMH

4.7 ± 3.8

3.8 ± 3.0

0.000

4.1 ± 3.1

3.9 ± 3.1

0.347

 AFC

15.5 ± 7.4

13.9 ± 6.7

0.001

14.1 ± 6.9

14.1 ± 6.8

0.936

Stimulation Protocol n (%)

 Agonist

195 (37.3)

131 (41.5)

0.041

120 (42.4)

116 (41.0)

0.774

 Antagonist

305 (58.3)

161 (50.9)

147 (51.9)

147 (51.9)

 Others

23 (4.4)

24 (7.6)

16 (5.7)

20 (7.1)

 Total Gn (IU)

2532.8 ± 975.0

2789.2 ± 1008.5

0.000

2716.5 ± 970.0

2736.0 ± 979.9

0.811

 Duration of Gn (day)

10.1 ± 1.8

10.2 ± 2.3

0.504

10.4 ± 1.8

10.2 ± 2.3

0.488

Fertilization method n (%)

 IVF

352 (67.3)

217 (68.7)

0.681

184 (65.0)

193 (68.2)

0.422

 ICSI

171 (32.7)

99 (31.3)

99 (35.0)

90 (31.8)

 Oocytes retrieved, n

13.4 ± 6.7

12.4 ± 6.0

0.017

12.9 ± 6.6

12.5 ± 5.9

0.348

 Number of transplantable embryos (n)

9.9 ± 5.6

9.2 ± 4.5

0.041

9.5 ± 5.5

9.2 ± 4.3

0.455

 Number of top-quality embryos (n)

4.2 ± 3.5

3.4 ± 2.9

0.000

3.9 ± 3.3

3.5 ± 2.9

0.118

 Endometrial thickness (mm)

9.8 ± 1.9

9.8 ± 2.0

0.970

9.7 ± 1.9

9.7 ± 2.0

0.636

Endometrial preparation protocol n (%)

 Nature

288 (55.1)

132 (41.8)

0.000

140 (49.5)

130 (45.9)

0.626

 HRT

167 (31.9)

102 (32.3)

88 (31.1)

90 (31.8)

 HRT + GnRHa

68 (13.0)

82 (25.9)

55 (19.4)

63 (22.3)

Day of blastocyst transfer (%)

 Day 5

389 (74.4)

202 (63.9)

0.001

183 (64.7)

183 (64.7)

1.000

 Day 6

134 (25.6)

114 (36.1)

100 (35.3)

100 (35.3)

  1. Values are expressed as n (%), percentage (%) or mean ± standard deviation (SD) unless otherwise stated. Variables presented in the part of statistical analysis were used for PS matching. P-values in bold depict statistical significance (P < 0.05) in comparison between SET-GQE and DET-GQE + PQE
  2. SET Single embryo transfer, DET Double embryo transfer, GQE Good quality embryo, PQE Poor quality embryo, BMI Body mass index, AMH Anti-Müllerian hormone, AFC Antral Follicular Count, Gn Gonadotropin, IVF In vitro fertilization, ICSI Intracytoplasmic sperm injection, HRT Hormone replacement treatment, GnRHa Gonadotropin-releasing hormone agonist