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Table 1 Baseline characteristics between single good-quality cleavage-stage embryo transfer and transfer of a second poor-quality embryo with a good-quality embryo before and after PS matching

From: Effect of frozen-thawed embryo transfer with a poor-quality embryo and a good-quality embryo on pregnancy and neonatal outcomes

Variable

Before matching

After matching

SET- GQE (N = 201)

DET- GQE + PQE (N = 421)

P value

SET- GQE (N = 169)

DET- GQE + PQE (N = 169)

P value

Maternal age (y)

32.6 ± 5.1

34.3 ± 5.2

0.000

33.1 ± 5.2

33.2 ± 5.2

0.900

Paternal age (y)

34.5 ± 5.9

35.9 ± 6.2

0.006

34.9 ± 6.0

35.2 ± 6.4

0.592

BMI (kg/m2)

21.9 ± 2.9

22.5 ± 3.4

0.012

22.0 ± 3.0

21.9 ± 3.0

0.610

Duration of infertility (y)

3.2 ± 2.5

3.3 ± 2.5

0.486

3.3 ± 2.6

3.4 ± 2.3

0.691

Type of infertility n (%)

 Primary

135 (67.2)

257 (61.0)

0.139

112 (66.3)

106 (62.7)

0.495

 Secondary

66 (32.8)

164 (39.0)

57 (33.7)

63 (37.3)

 Basal FSH (IU/L)

9.8 ± 6.0

10.1 ± 6.3

0.589

10.1 ± 6.1

10.3 ± 6.1

0.720

 AMH

3.8 ± 3.3

3.2 ± 3.0

0.027

3.5 ± 3.0

3.3 ± 2.8

0.457

 AFC

13.3 ± 8.0

11.5 ± 7.3

0.005

12.6 ± 8.0

12.2 ± 7.4

0.631

Stimulation Protocol n (%)

 Agonist

54 (26.9)

137 (32.5)

0.154

44 (26.0)

51 (30.2)

0.612

 Antagonist

114 (56.7)

204 (48.5)

94 (55.6)

85 (50.3)

 Others

33 (16.4)

80 (19.0)

31 (18.3)

33 (19.5)

 Total Gn (IU)

2364.6 ± 1080.2

2666.9 ± 1172.1

0.002

2386.0 ± 1117.0

2524.2 ± 1161.6

0.266

 Duration of Gn (day)

9.6 ± 2.5

9.9 ± 2.6

0.189

9.5 ± 2.6

9.8 ± 2.7

0.360

Fertilization method n (%)

 IVF

120 (59.7)

224 (53.2)

0.128

96 (56.8)

100 (59.2)

0.659

 ICSI

81 (40.3)

197 (46.8)

73 (43.2)

69 (40.8)

 Oocytes retrieved (n)

10.6 ± 7.5

9.6 ± 6.2

0.111

9.7 ± 7.0

9.9 ± 6.3

0.733

 Number of transplantable embryos (n)

7.4 ± 5.6

6.6 ± 4.3

0.073

6.5 ± 5.0

6.7 ± 4.4

0.729

 Number of top-quality embryos (n)

3.2 ± 2.4

2.1 ± 1.6

0.000

2.6 ± 2.1

2.6 ± 1.9

0.827

 Endometrial thickness (mm)

9.9 ± 1.9

9.7 ± 2.0

0.264

9.8 ± 1.9

9.8 ± 2.0

0.939

Endometrial preparation protocol n (%)

 Nature

100 (49.8)

193 (45.8)

0.299

77 (45.6)

88 (52.1)

0.406

 HRT

69 (34.3)

139 (33.0)

62 (36.7)

51 (30.2)

 HRT + GnRHa

32 (15.9)

89 (21.1)

30 (17.8)

30 (17.8)

  1. Values are expressed as n (%), percentage (%) or mean ± standard deviation (SD) unless otherwise stated. Variables presented in the part of statistical analysis were used for PS matching. P-values in bold depict statistical significance (P < 0.05) in comparison between SET-GQE and DET-GQE + PQE
  2. SET Single embryo transfer, DET Double embryo transfer, GQE Good quality embryo, PQE Poor quality embryo, BMI Body mass index, AMH Anti-Müllerian hormone, AFC Antral Follicular Count, Gn Gonadotropin, IVF In vitro fertilization, ICSI Intracytoplasmic sperm injection, HRT Hormone replacement treatment, GnRHa Gonadotropin-releasing hormone agonist
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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