Fig. 1

IFN-λ regulates miRNA expression in human endometrial cells. a Experimental scheme used for studying the miRNA expression profiles of Ishikawa cells treated with IFN-λ. Differentially expressed miRNAs were screened using a heat map according to the groups indicated. Blue and red indicate low and high expression, respectively. b Expression of each miRNA was determined using qPCR. IFN-λ enhances miR-30a-3p and miR-122-5p expression, and inhibits miR-130b-3p, miR-145-5p, miR-93-3p, and miR-124-3p expression. Data represent the mean ± SD of three independent experiments, *P < 0.05; **P < 0.01 (Student’s t-test)