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Table 1 Background and treatment characteristics

From: Serum erythropoietin level is increased during stimulation for IVF but not in OHSS

Background information

IVF Group (N = 24)

OHSS Group (N = 35)

p

Age (yrs)a

34.0 ± 2.6

33.1 ± 3.5

0.26

BMI (kg/m²)a

23.6 ± 3.4

22.5 ± 3.2

0.23

Smokingb

   

0.35

Yes

2 (8.3)

1 (2.9)

 

No

22 (91.7)

34 (97.1)

 

Previous OHSSb

   

0.12

Yes

6 (26.1)

3 (10)

 

No

17 (73.9)

27 (90)

 

PCOb

   

0.16

 

Yes

6 (26.1)

13 (44.8)

 

No

17 (73.9)

16 (55.2)

 

Duration of infertility (yrs)a

 

4.9 ± 2.9

4.1 ± 2.3

0.28

AMH (µg/L)c,d

3.6 (3.0-4.1)

2.7 (1.9–4.2)

0.25

Treatment characteristics

IVF Group (N = 24)

Early (N = 25)

Late (N = 12)

 

Protocolb

    

< 0.05

Agonist

24 (100)

17 (68)

9 (75)

 

Antagonist

0 (0)

8 (32)

3 (25)

 

FSH starting dose (IU)c

 

150 (150–200)

150 (150–225)

150 (150–250)

0.69

FSH cumulative dose (IU)c

 

1650 (1650–2000)

1375 (1200–1600)

1688 (1500–2400)

0.08

Number of folliclesc

17 (14–26)

38 (29–48)

21 (21–25)

< 0.001

E2 OPU2 (nmol/L)c

3.7 (2.1–4.2)

NA

NA

NA

E2 Admission (nmol/L)c,e

NA

9.7 (7.2–13.5)

7.4 (6.5–10.1)

0.44

E2 OPU7 (nmol/L)c

3.0 (2.3–4.1)

8.6 (5.9–11.8)

NA

< 0.001

Luteal supportb

    

0.19

Vaginal progesterone

24 (100)

15 (100)

11 (91.7)

 

hCG

0 (0)

0 (0)

1 (8.3)

 

Embryo transferb

    

< 0.001

None

0 (0)

10 (40)

0 (0)

 

One embryo

23 (95.8)

14 (56)

9 (75)

 

Two embryos

1 (4.2)

1 (4)

3 (25)

Pregnancyb

    

< 0.001

Yes

12 (50)

6 (24)

12 (100)

No

12 (50)

19 (76)

0 (0)

  1. BMI = body mass index, PCO = polycystic ovaries, AMH = anti-Müllerian hormone, FSH = follicle stimulating hormone, E2 = oestradiol, OPUn = days from ovarian pick-up, hCG = human chorionic gonadotropin. NA = not applicable. The data are expressed as amean ± standard deviation for parametric variables, bnumber of women (percentage) for categorical variables or cmedian (95% confidence interval) for non-parametric variables. dAMH was analysed at OPU7. eMedian day for admission was OPU4 for early OHSS and OPU14 for late OHSS. Group differences were analysed with independent samples T-test test for parametric variables, Kruskal-Wallis or Mann-Whitney U test for non-parametric variables and chi-square test for categorical parameters