Table 2 Ovarian response, embryology, and safety outcomes

 Duration of stimulation (days)

9.95 ± 1.48

8.69 ± 1.63

< 0.001^c

 Total dose of follitropin delta (μg)

119.4 ± 17.7

104 ± 20.2

< 0.001^c

 Total dose of menotropin

1492.5 ± 222.0

0

–

 Cancelled due to poor response

2 (4.5%)

14 (4.7%)

> 0.999^b

 Estradiol on trigger day (pg/mL)

2150.2 ± 1093.3

1372.8 ± 741.7

< 0.001^c

 Oocytes retrieved

9.07 ± 5.56

7.54 ± 4.57

0.058^c

 Ovarian response

0.276^b

  < 4 eggs

6 (13.6%)

47 (16%)

  4 - 7 eggs

16 (36.4%)

118 (40.1%)

  8 - 14 eggs

16 (36.4%)

110 (37.4%)

  ≥ 15 eggs

6 (13.6%)

19 (6.5%)

 Zygotes (2 PN)

5.1 (3.05)

4.2 (3.10)

0.040^c

 Fertilization rate

85.9 ± 15.8

56.7 ± 25.4

< 0.001^c

 Blastocysts (total)

3.10 ± 2.66

2.42 ± 2.22

0.030^c

 Blastocysts (top quality)

1.80 ± 2.01

1.37 ± 1.71

0.017^c

 Blastocysts transferred (fresh or thawed)

< 0.001^b

  No transfer

7 (15.9%)

50 (16.84%)

  1

26 (59.1%)

232 (78.11%)

  2

11 (25%)

15 (5.05%)

 Cryopreserved surplus blastocysts

1.00 ± 1.53

1.03 ± 1.17

0.486^c

 Individuals with frozen embryos

26 (61.9%)

154 (51.9%)

0.291^a

 Preventive measures for OHSS (GnRHa trigger, freeze-all)

6 (13.6%)

2 (0.6%)

< 0.001^b

 Early OHSS

2 (4.5%)

2 (0.7%)

0.082^b

 OHSS any degree

2 (4.5%)

4 (1.3%)

0.174^b