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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Elevated first-trimester neutrophil elastase and proteinase 3 increase the risk of gestational diabetes mellitus and adverse fetal outcomes

Fig. 2

Simple linear regression analysis of association of NE and PR3 with first-trimester neutrophil count, pre-pregnancy BMI, newborn weight, 1h PG, 2h PG and OGTT area. First-trimester neutrophil count for NE β = 0.24, F (1, 453) = 28.61, adjusted R2 = 0.06; P < 0.001, for PR3 β = 0.22, F (1, 468) = 24.84, adjusted R2 = 0.05, P < 0.001 (A and G); pre-pregnancy BMI for NE β = 0.14, F (1, 472) = 9.61, adjusted R2 = 0.02, P = 0.002, for PR3 β = 0.10; F (1, 486) = 5.15, adjusted R2 = 0.01, P = 0.024 (B and H); newborn weight for NE β = 0.13, F (1, 328) = 5.49, adjusted R2 = 0.01, P = 0. 020, for PR3 β = 0.11, F (1, 330.00) = 3.90, adjusted R2 = 0.01, P = 0.049 (C and I); 1h PG for NE β = 0.18, F (1, 457) = 16.08, adjusted R2= 0.03, P < 0.001, for PR3 β = 0.16, F (1, 472) = 11.81, adjusted R2= 0.02, P = 0.001 (D and J); 2h PG for NE β = 0.16, F (1, 460) = 12.09, adjusted R2 = 0.02, P = 0.001, for PR3 β = 0.13, F (1, 475) = 8.38, adjusted R2 = 0.02, P = 0.004 (E and K); and OGTT area for NE β = 0.20, F (1, 450) = 17.97, adjusted R2 = 0.04, P < 0.001, for PR3 β = 0.16, F (1, 465) = 11.91, adjusted R2 = 0.02, P = 0.001 (F and L). NE and PR3 were log transformed for analysis

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