Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes

Table 1 Detection rate of Y chromosome microdeletion in different sperm count phenotype

Group	Normal	Mild oligozoospermia	Severe oligozoospermia	Cryptozoospermia	Azoospermia
Number of patients	2412	703	615	56	928
Number of patients with AZF deletion	4^a	8^b	34^c	40^d	70^e
Detection rate, %^f	0.17	1.13	5.53	71.43	7.54

^aTwo patients had sY86 deletions, and two patients had sY254, sY255, and sY152 deletions
^bOne patient had an sY86 deletion, and seven patients had sY254, sY255, and sY152 deletions
^c34 patients had sY254, sY255, and sY152 deletions
^d40 patients had sY254, sY255, and sY152 deletions
^e24 patients had sY254, sY255, and sY152 deletions, one patient had sY84 and sY86 deletions, eight patients had sY127 and sY134 deletions, three patients had sY254, sY255, sY145, and sY152 deletions, eight patients had sY127, sY134, sY254, sY255, and sY152 deletions, 22 patients had sY127, sY134, sY254, sY255, sY145, and sY152 deletions, and four patients had all eight STS deletions
^fThe detection rates between the severe oligozoospermia and azoospermia groups showed no significant difference (P = 0.122). However, significant differences were observed in the pairwise comparisons between the other groups (P < 0.05)
Abbreviations: AZF, azoospermia factor

ISSN: 1477-7827