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Table 3 Clinical features and pregnancy outcomes of endometriosis group and control group

From: 25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells

Group

Control group

Endometriosis group

Age (years)

30.11 ± 3.188

30.84 ± 3.844

BMI(kg/m2)

22.99 ± 2.850

22.67 ± 3.138

History of adverse pregnancy (times)

0.00(0.00,1.00)

0.00(0.00,1.00)

Infertility years (years)

3.00(2.00,5.00)

3.00(2.00,5.00)

Assisted reproduction history (times)

0.00(0.00,1.00)

0.00(0.00,1.00)

FSH(U/L)

6.40(5.40,7.90)

6.30(5.50,8.20)

LH(U/L)

5.00(3.60,7.20)

5.00(3.80,7.00)

E2(pg/mL)

36.60(24.10,54.30)

37.00(23.00,50.20)

AMH(ng/mL)

2.21(1.43,3.20)

1.92(1.33,2.89)

P(ng/mL)

0.22(-0.21,0.44)

0.30(0.12,0.40)

PRL(ng/mL)

18.5(13.40,25.20)

20.00(15.20, 28.90)

Number of eggs harvested

16.00(10.00,23.00)

14.00(10.00,23.00)

MII rate(%)

85.6(3077/3596)

83.4(990/1187)

High quality embryo rate(%)

42.5(491/1154)

37.5(147/392)

Number of transplantable embryos

4.00(3.00,6.00)

5.00(3.00,7.00)

Number of transplanted embryos

1.00(1.00,2.00)

1.00(1.00,2.00)

endometrial thickness at the day of Embryo transfer (mm)

10.00(8.50,11.00)

10.00(9.00,11.00)

Clinical pregnancy rate (%)

71.2(156/219)

58.6(44/75)*

Abortion rate (%)

17.9(28/156)

11.3(5/44)

Ectopic pregnancy rate (%)

3.84(6/156)

4.54(2/44)

Live birth rate (%)

54.7(120/219)

49.3(37/75)

  1. Abbr. BMI Body Mass index, FSH follicle-stimulating hormone, LH basic luteinizing hormone, E2, basal estradiol, AMH anti-Mullerian hormone, P progesterone, PRL prolactin; High quality embryo = Grade 1 + Grade 2 embryos. Grade 1 embryos had 6–10 cells, a fragmentation of 0–10%, and perfect symmetry; Grade 2 embryos had either 6–10 cells with fragmentation of 0–25% and moderate symmetry or they had 4–6 or > 10 cells with fragmentation of 0–10% and perfect symmetry. High quality embryo rate = number of (Grade 1 + Grade 2 embryo)/total number of retrieved embryos × 100%. Transferable embryo: The embryo has more than 4 cells, the fragment content is < 25%, the size of most cells is consistent with the developmental stage, and there is no evidence of multiple nuclei. MII rate = MII ovum/ovum harvested × 100%; Clinical pregnancy rate = clinical pregnancy number/transplant cycle number × 100%; Abortion rate = number of abortions/number of clinical pregnancies × 100%; Ectopic pregnancy rate = ectopic pregnancy number/clinical pregnancy number × 100%; Live birth rate = number of live births/transplant cycles × 100%
  2. *p < 0.05