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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells

Fig. 4

Construction of the PPI network of differentially expressed genes in reproductive system development. (A) PPI network of the DEGs enriched in negative regulation of secretion, cellular response to oxidative stress and regulation of vesicle trafficking. The nodes represent genes. The size of nodes indicates the number of connections. The edges denote the interactions between two genes, and the width of an edge denotes the score of a genetic interaction. (B-C) A permutation test of the network genes and connections was performed with 100,000 iterations

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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