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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Nuclear-cytoplasmic asynchrony in oocyte maturation caused by TUBB8 variants via impairing microtubule function: a novel pathogenic mechanism

Fig. 4

Abnormal chromosome distribution in mouse oocytes caused by TUBB8 variants. (A) Chromosome plate structure in the spindles of mouse oocytes at the metaphase II (MII) stage, scale bar = 5 μm. (B) Statistical analysis of chromosome plate width in the spindles of mouse oocytes at the MII stage. Data are presented as mean ± standard deviation (mean ± SD), *P < 0.05; **P < 0.01

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