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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Nuclear-cytoplasmic asynchrony in oocyte maturation caused by TUBB8 variants via impairing microtubule function: a novel pathogenic mechanism

Fig. 2

TUBB8 variants lead to abnormal spindle morphology in mouse oocytes. (A) Representative images of spindle morphology in mouse oocytes at the metaphase II (MII) stage, with Flag indicating the signal of exogenous protein transduction, scale bar = 5 μm. (B) Abnormal spindle types in mouse oocytes at the MII stage, with Flag indicating the signal of exogenous protein transduction, and the white dashed box indicating the first polar body, scale bar = 5 μm. (C) Statistical analysis of the percentage of abnormal spindles in mouse oocytes. Data are presented as mean ± standard deviation (mean ± SD), **P < 0.01; ***P < 0.001

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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