Table 4 Study characteristics of 2 studies about Vitamin supplementation impact on fertility
Study | Country | Study type | Sample size(intervention/control) | Age(Mean ± SD) | Type and duration of supplementation | outcome | |
|---|---|---|---|---|---|---|---|
Intervention group | Placebo group | ||||||
Xiang Lu et al.,2018 | China | RCT | 137/108 | Intervention: 31.5 ± 3.5 Control:31.9 ± 3.00 | Vitamin C 1000 mg/ day of 2mo | Non-treatment | retrieved oocyte rate, implantation rate, and clinical pregnancy rate unaffected;but ameliorating the quality of oocytes and embryos |
Jennifer Mier-Cabrera et al;2007 [37] | Mexico | RCT | (16/18) | Intervention: 32.7 ± 2.36 Control: 32.8 ± 2.49 | vitaminE84mg + vitaminC343mg for 6 | Placebo pills for 6weeks | the pregnancy rate unaffected |