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Table 3 Functional analysis results of downregulated core differential genes

From: Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis

Function

Key genes

Cell cycle

CDC6, CDC20, TUBA4A, TUBG1, CCNA1, CCNB1, CCNA2, CDT1, CDK1, CCNE1, MCM4

Progesterone-mediated oocyte maturation and oocyte meiosis pathway

BRCA1, E2F1, CHEK1, TOPBP1, MAD2L1, HIST3H3, BLM, UBE2C, MCM4

Biological enzyme activation

BIRC5, RAD51