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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Fig. 4

Expression levels of the candidate proteins in the epididymis-derived exosomes and caput epididymis. A The expression of candidate proteins PDIA3, RRBP1 and CRELD2 in the exosomes detected by Western blot analysis, and their expression levels were normalized to TSG101 expression (exosome marker). All data were shown as mean ± SD, *P < 0.05, ***P < 0.001, ****P < 0.0001. B The candidate proteins PDIA3, RRBP1 and CRELD2 were widely expressed in the epithelial cells lining the lumen of caput epididymis (bar = 50 μm). C PPI showed the relationship between the candidate proteins with the other differentially expressed proteins resolved in the proteomic data. The diamonds represent the candidate proteins and the circles represent the associated proteins. The red coloration indicates the up-regulated proteins whereas the green coloration indicates the down-regulated proteins

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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