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Table 3 The DNA Methylation levels of selected candidate genes in the mild asthenospermia group and normozoospermia group

From: Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA

Gene

Position

Case Value

Control Value

P

IGF-2

169

0.014 ± 0.007

0.011 ± 0.006

0.025

IGF-2

55

0.007 ± 0.004

0.006 ± 0.003

0.018

KCNQ1

29

0.004 ± 0.006

0.007 ± 0.009

0.017

MEST

37

0.012 ± 0.006

0.014 ± 0.007

0.035

MEST

58

0.007 ± 0.004

0.009 ± 0.007

0.028

MEST

186

0.007 ± 0.007

0.011 ± 0.010

0.004

  1. Case:asthenospermia group; Control:normozoospermia group; Bold values was statistically significant (P < 0.05)
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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