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Table 2 Comparison of laboratory parameters and clinical outcomes

From: Is early-follicular long-acting GnRH agonist protocol an alternative for patients with polycystic ovary syndrome undergoing in vitro fertilization?

 

MLSL

EFLL

P value

Length of stimulation (d)

11.894 ± 2.139

14.725 ± 2.660

 < 0.001

Total dosage of Gn (IU)

1666.979 ± 706.009

2263.929 ± 909.607

 < 0.001

E2 on trigger day (pg/ml)

6360.655 ± 3283.401

3992.922 ± 2227.219

 < 0.001

LH on trigger day (mIU/ml)

1.446 ± 0.693

0.738 ± 0.957

 < 0.001

Endometrial thickness on trigger day (mm)

11.240 ± 2.554

12.134 ± 2.360

 < 0.001

No. of oocytes retrieved (n)

16.906 ± 7.813

18.078 ± 7.978

 < 0.001

No. of 2PN (n)

10.905 ± 5.987

10.852 ± 5.963

0.804

No. of transferable embryos

6.559 ± 4.004

5.832 ± 3.415

 < 0.001

High-quality embryos rate (%)

59.37 (7531/12684)

54.23 (13892/25619)

 < 0.001

Moderate to severe OHSS rate (%)

2.46 (29/1179)

3.22 (77/2390)

0.207

“Freezing all” for high risk of OHSS (%)

32.06 (378/1179)

24.27 (580/2390)

 < 0.001

Implantation rate (%)

37.85 (436/1152)

56.76 (1368/2410)

 < 0.001

Biochemical pregnancy rate (%)

58.87 (385/654)

79.23 (1120/1413)

 < 0.001

Clinical pregnancy rate (%)

53.82 (352/654)

75.23 (1063/1413)

 < 0.001

Live birth rate (%)

42.05 (275/654)

63.27 (894/1413)

0.010

Full-term birth rate (%)

32.87 (215/654)

50.88 (719/1413)

 < 0.001

Spontaneous abortion rate (%)

8.26 (54/654)

10.83 (153/1413)

0.070

PTB rate (%)

8.10 (53/654)

11.11 (157/1413)

0.518

  1. Note: Categorical data: % (n/N)
  2. Gn gonadotropin, LH luteinizing hormone, OHSS ovarian hyperstimulation syndrome, PTB preterm birth