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Table 1 Effects of temperature and Na+ gradient on the uptake of monoamines by placental cells

From: Functional reorganization of monoamine transport systems during villous trophoblast differentiation: evidence of distinct differences between primary human trophoblasts and BeWo cells

 

Uptake at 4 °C

Uptake in absence of Na+

Monoamine

Cell model

mean (%)

SD

p value

mean (%)

SD

p value

Serotonin

PHT-CTB

15.56

11.50

0.0014 **

19.41

10.19

0.0024 **

PHT-STB

12.96

6.87

0.0001 ***

23.36

6.94

0.0023 **

BeWo-CTB

75.56

13.70

0.0201 *

48.09

15.72

0.0022 **

BeWo-STB

32.46

5.15

0.0078 **

35.36

10.97

0.0049 **

Norepinephrine

PHT-CTB

52.40

14.29

0.1336

65.63

22.82

0.0782

PHT-STB

59.76

6.61

0.1306

82.23

18.19

0.1960

BeWo-CTB

106.60

14.58

0.6296

-

-

-

BeWo-STB

85.95

20.15

0.287

95.37

29.54

0.4657

Dopamine

PHT-CTB

80.70

12.54

0.0925

71.19

31.19

0.4075

PHT-STB

91.07

28.80

0.8170

72.44

39.95

0.3676

BeWo-CTB

100.10

9.04

0.9585

-

-

-

BeWo-STB

70.62

21.04

0.0663

75.48

18.97

0.960

  1. Values shown are percentages of monoamine uptake at 4 °C/in the absence of Na+ relative to uptake at room temperature and in the presence of Na+ (and p values of the differences). Presented data are means ± SD (n ≥ 4). The statistical significance of differences was evaluated using paired t-tests: *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001