Reproductive Biology and Endocrinology

Table 4 Comparisons between ERK 2 genotypes and clinical characteristics, biochemical-hormonal parameters

From: The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis

	PCOS-ERK 2		Control-ERK 2		P^a
Parameters	P-GG	P-GC	C-GG	C-GC
BMI	25,49 ± 3,88^b	31,5 ± 5,38^c,d	26,3 ± 6,25	27,29 ± 5,43	≤ 0.001
FGS	9,76 ± 3,04^b,f	14,3 ± 6,52^c,d	5,20 ± 1,67	8,36 ± 1,32	≤ 0.001
HOMA-IR	2,24 ± 1,55^b	3,40 ± 1,97 ^c,d	1,76 ± 0,79	1,84 ± 1,47	≤ 0.001
CRP	11,16 ± 2,59^f	12,03 ± 2,80^c	5,39 ± 2,24^g	10,67 ± 5,45	≤ 0.001
Total testesteron	0,72 ± 0,36^f	0,75 ± 0,37^c	0,48 ± 0,2	0,6 ± 0,18	≤ 0.001
Triglyceride	122 ± 53^e,f	114,95 ± 46,03^c,d	93,17 ± 40,87	86,81 ± 25,7	≤ 0.001
Total Cholesterol	191,52 ± 41,98^f	192,7 ± 45,03^c	164,87 ± 27	186,09 ± 35,4	≤ 0.001
LDL	113,31 ± 37,75	119,5 ± 44,28^c	96,26 ± 23,8	111,27 ± 32,43	≤ 0.001
HDL	53,80 ± 10,51	50,23 ± 10,24^d	51,12 ± 11,12	58,63 ± 11,39	≤ 0.001

Data presented as Mean ± SD and p < 0.05 accepted as statistically significant
^a Groups were compared between P-GG,P-GC,C-GG and C-GC with; one-way ANOVA test
^bp < 0.05 (P-GG vs P-GC); Tamhane test
^cp < 0.05 (P-GC vs C-GG); Tamhane test
^dp < 0.05 (P-GC vs C-GC); Tamhane test
^ep < 0.05 (P-GG vs C-GC); Tamhane test
^fp < 0.05 (P-GG vs C-GG); Tamhane test
^gp < 0.05 (C-GG vs C-GC); Tamhane test
P: PCOS (Polycystic Ovary Sydrome) Group
C: Control Group

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ISSN: 1477-7827

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