Reproductive Biology and Endocrinology

Table 3 Comparisons between ERK 1 genotypes and clinical characteristics, biochemical-hormonal parameters

From: The role of ERK-1 and ERK-2 gene polymorphisms in PCOS pathogenesis

	PCOS-ERK 1		Control-ERK 1		P^a
Parameters	P-GG	P-GA	C-GG	C-GA
BMI	27,3 ± 5,06^b	30,68 ± 5,72^c	26,11 ± 5,41	28,38 ± 8,15	≤ 0.001
FGS	11,08 ± 4,01^b,f	13,73 ± 6,9^c	5,48 ± 1,84	7,5 ± 2,16^e	≤ 0.001
HOMA-IR	2,70 ± 2,12^f	3,13 ± 1,63^c,d	1,75 ± 0,97	1,89 ± 0,96	≤ 0.001
CRP	11,38 ± 3,05^f	11,96 ± 2,38^c	6,40 ± 4,06	7,06 ± 2,86^e	≤ 0.001
Total testesteron	0,71 ± 0,33^f	0,77 ± 0,39^c,d	0,53 ± 0,19	0,4 ± 0,21^e	≤ 0.001
Triglyceride	125,54 ± 50,53^f	110,46 ± 46,54	93,43 ± 39,7	85,1 ± 30,46^e	≤ 0.001
Total Cholesterol	196,52 ± 41,65^f	188,07 ± 45,39^c	168,9 ± 26,18	171,7 ± 43,5	≤ 0.001
LDL	116,89 ± 38,3^f	117,01 ± 44,92	99,28 ± 21,4	100,4 ± 42,05	0.006
HDL	54,56 ± 10,77	48,96 ± 9,44	52,53 ± 12,75	53,6 ± 3,87	0.64

Data presented as Mean ± SD and p < 0.05 accepted as statistically significant
^a Groups were compared between P-GG,P-GA,C-GG and C-GA with; one-way ANOVA test
^bp < 0.05 (P-GG vs P-GA); Tamhane test
^cp < 0.05 (P-GA vs C-GG); Tamhane test
^dp < 0.05 (P-GA vs C-GA); Tamhane test
^ep < 0.05 (P-GG vs C-GA); Tamhane test
^fp < 0.05 (P-GG vs C-GG); Tamhane test
P: PCOS (Polycystic Ovary Sydrome) Group
C: Control Group

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