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Table 2 Basic patient characteristics and results of hormonal testing in FHA women with and without PCOM

From: Basal and dynamic relationships between serum anti-Müllerian hormone and gonadotropins in patients with functional hypothalamic amenorrhea, with or without polycystic ovarian morphology

 

FHA without PCOM (n = 37)

FHA with PCOM (n = 27)

Controls (n = 32)

p

Age (years)

26 (21;30)

26 (21;28)

26 (23;28)

0.731

BMI (kg/m2)

20.0 (18.5;21.6)

20.4 (18.6;23.2)

21.5 (19.6;23.6)

0.131

TSH (IU/mL)

1.78 (1.17;2.04)

1.49 (1.08;2.36)

1.41 (1.05;1.93)

0.400

FSH (mIU/mL)

4.0 (2.6;6.1)

4.6 (3.5;6.5)

5.7 (4.4;7.6)

0.034

LH (mIU/mL)

2.6 (1.2;4.9)b

2.6 (1.3;6.3)c

4.7 (3.4;7.0)b c

0.001

Prolactin (ng/mL)

7.9 (6.5;12.2)b

9.3 (6.6;13.1)

11.8 (9.0;15.4)b

0.013

Estradiol (pg/mL)

23 (16;35)b

30 (11;45)c

71 (50;97)b c

 < 0.001

Testosterone (pg/mL)

0.22 (0.13;0.30)

0.22 (0.15;0.30)

0.25 (0.17;0.31)

0.695

Androstenedione (ng/mL)

1.29 (0.93;2.10)

1.65 (1.09;2.62)

1.54 (1.18;2.04)

0.269

DHEAS (µg/mL)

2.01 (1.47;3.25

2.33 (1.56;2.84)

2.18 (1.76;2.74)

0.926

SHBG (nmol/L)

79.4 (60.3;120.9)

68.3 (37.7;99.8)

81.2 (61.;104.5)

0.144

AMH (ng/mL)

2.03 (1.40;2.50)a b

6.38 (4.34;10.10)a c

3.08 (2.24;4.10)b c

 < 0.001

  1. Variables are expressed as median (IQR); non-parametric Anovas with post hoc Bonferonni correction were perfomed
  2. asignificantly different between FHA without PCOM and FHA with PCOM
  3. bsignificantly different between FHA without PCOM and controls
  4. csignificantly different between FHA with PCOM and controls