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Table 1 Basic patient characteristics and results of hormonal testing in women with FHA and healthy control women

From: Basal and dynamic relationships between serum anti-Müllerian hormone and gonadotropins in patients with functional hypothalamic amenorrhea, with or without polycystic ovarian morphology

 

FHA (n = 64)

Controls (n = 32)

p

Underweight < 18.5 kg/m2 a,b

12 (18.8%)

-

-

weight loss > 10kga,b

16 (25.0%)

-

-

Eating disordera,b

19 (29.7%)

-

-

High level of exercisea,b

26 (40.6%)

-

-

History of emotionally stressful eventsa,b

15 (23.4%)

-

-

Age (years)c

26 (21;29)

26 (23;28)

0.551

BMI (kg/m2)c

20.0 (18.6;22.4)

21.5 (19.6;23.6)

0.064

TSH (IU/mL)c

1.67 (1.15;2.16)

1.41 (1.05;1.93)

0.186

FSH (mIU/mL)c

4.5 (3.2;6.2)

5.6 (4.4;6.7)

0.026

LH (mIU/mL)c

2.6 (1.3;5.3)

4.7 (3.6;6.7)

 < 0.001

Prolactin (ng/mL)c

8.3 (6.6;12.5)

12.2 (9.4;14.0)

0.003

Oestradiol (pg/mL)c

24 (14;37)

59 (47;68)

 < 0.001

Testosterone (pg/mL)c

0.22 (0.13;0.30)

0.24 (0.17;0.31)

0.479

Androstenedione (ng/mL)c

1.45 (0.98;2.37)

1.58 (1.19;2.04)

0.825

DHEAS (µg/mL)c

2.16 (1.53;3.06)

2.16 (1.80;2.74)

0.963

SHBG (nmol/L)c

73.2 (55.1;104.0)

81.2 (61.1;104.5)

0.397

AMH (ng/mL)c

2.57 (1.57;6.18)

3.08 (2.24;4.07)

0.960

  1. Variables are expressed as anumbers (frequencies) or.cmedian (IQR)
  2. Multiple nominations are possible for bFHA causes