Fig. 3
From: Activation of α7 nicotinic acetylcholine receptor retards the development of endometriosis
Therapeutic potentials of α7nAChR activation in treating deep endometriosis in mouse. A Dynamic changes in mean bodyweight in the Control and the PNU-282987 groups. B Boxplots of the lesion weight from the two groups of mice. C Dynamic changes in mean hotplate latency, tested at the indicated time points, from the two groups of mice. Representative immunostaining results for E-cadherin D, α-SMA E, desmin F and SM-MHC G in endometriotic lesions from Control and PNU-282987 treated mice (left panel), along the boxplots summarizing the staining data (right panel). H Representative images of Masson trichrome staining in endometriotic lesions in Control and PNU-282987 mice (left panel), along with the boxplot summarizing the staining data (right panel). Magnification = 400 × , scale bar = 50 μm. n = 8 in both groups. Symbols for statistical significance levels: NS: p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001