Fig. 1
From: Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction
The structure of kisspeptins in humans. Kisspeptins are derived from a 145-amino-acid prepro-kisspeptin (encoded by KISS1 gene). The cleavage sites at 68 and 121 of prepro-kisspeptin lead to the production of the RF-amidated KP54. Shorter kisspeptins (KP-10, − 13, and − 14) share a common C terminus and RF-amidated motif with KP54. Modified from [12, 17]