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Table 1 The clinical information of patients whose testis tissue collected in the reproductive medicine center(x ± s)

From: miR-188-3p-targeted regulation of ATG7 affects cell autophagy in patients with nonobstructive azoospermia

Index

NOA group

(n = 16)

Control group

(n = 16)

P-value

Age (years)

27.25 ± 3.61

29.50 ± 5.03

0.233

FSH (IU/L)

21.30 ± 6.86*

5.13 ± 2.94

0.000

LH (IU/L)

10.44 ± 4.34*

4.64 ± 1.92

0.000

T (ng/ml)

3.27 ± 2.39

4.60 ± 2.12

0.053

PRL (ng/ml)

12.65 ± 4.82

9.91 ± 4.26

0.254

E2 (pg/ml)

20.59 ± 13.68

26.55 ± 9.10

0.143

P (ng/ml)

0.50 ± 0.27

3.11 ± 9.31

0.877

Left testis volume (ml)

7.44 ± 1.93*

13.44 ± 3.85

0.000

Right testis volume (ml)

8.00 ± 2.66*

13.44 ± 3.85

0.000

Number of patients with abnormal secondary sexual characteristics no./total no. (%)

0/16 (0)

0/16 (0)

1.000

Number of patients with varicocele no./total no. (%)

0/16 (0)

0/16 (0)

1.000

Number of patients with genital abnormalities no./total no. (%)

0/16 (0)

0/16 (0)

1.000

Number of patients with abnormal karyotype no./total no. (%)

0/16 (0)

0/16 (0)

1.000

Number of patients with Y chromosome microdeletions no./total no. (%)

0/16 (0)

0/16 (0)

1.000

  1. Plus–minus values are means ± SD. To convert values for estradiol to picomoles per liter, multiply by 3.671. To convert values for testosterone to nanomoles per liter, multiply by 3.467
  2. Explanation for the relevant abbreviations:
  3. FSH means Follicle-stimulating hormone, LH means Luteinizing hormone, T means Total testosterone, PRL means prolactin, E2 means Estradiol and P means Prog
  4. *Statistically significant difference compared with control group (P < 0.05)